Study finds widespread hantavirus exposure among Pacific Northwest rodent populations

	Pulmonology
	The latest pulmonology news from News Medical

	Study finds widespread hantavirus exposure among Pacific Northwest rodent populations The Sin Nombre virus – a hantavirus that can cause a deadly respiratory disease in humans – may be more widespread among rodent populations in parts of the Pacific Northwest than previously recognized.

	Oral AD109 improves sleep apnea severity but tolerability remains a challenge AD109, an investigational once-daily oral combination of aroxybutynin and atomoxetine, significantly improved airway obstruction and oxygenation in adults with mild-to-severe obstructive sleep apnea who could not use PAP therapy. However, symptom improvements did not clearly differ from placebo, and about one in five AD109 recipients discontinued treatment due to adverse events.

			Early lung damage patterns uncovered in children with cystic fibrosis Researchers have mapped how lung damage begins early in life for children with cystic fibrosis, providing new insights that will help reshape future care.

			ICU pneumonia mortality rates remain elevated in developing nations A scientific review published today in the NEJM Evidence journal, coordinated by the D'Or Institute for Research and Education (IDOR), evaluated outcomes of adults with community-acquired pneumonia (CAP) admitted to intensive care units (ICUs) in middle-income countries.

			Lung cancer cells change identity to resist medical treatments Cancer scientists have discovered that lung cancer cells can change their identity to resist treatment.

	Degrading mutant KRAS protein induces greater lung cancer regression KRAS is one of the oncogenes most frequently altered in cancer, mutated in approximately one-third of lung adenocarcinomas.

	Prenatal therapy for cystic fibrosis improves lifelong health outcomes This Cystic Fibrosis Awareness Month, Children's Hospital Colorado (Children's Colorado) is highlighting a growing shift in care: starting cystic fibrosis treatment before birth to improve lifelong health outcomes and reduce hospital stays.

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