Protein-based therapeutics have advanced disease treatment, yet downstream processing (DSP) remains complex and cost-intensive. Aggregation is a main quality risk, but complex to monitor, often requiring multiple instruments. This paper presents a unified approach for simultaneous subvisible and submicron particle characterization, that can improve DSP, product quality, and process control.
A new method of examining gene expression patterns called landscape transcriptomics may help pinpoint what causes bumble bees stress and could eventually give insight into why bee populations are declining overall, according to a study led by researchers at Penn State.
LncRNAs and circRNAs are key regulators of gene expression, influencing disease mechanisms and offering potential as biomarkers and therapeutic targets.
Researchers from Northwestern University have stumbled upon a previously unobserved function of a protein found in the cell nuclei of all flora and fauna.
Metabolic dysfunction-associated fatty liver disease (MAFLD) has become a growing global health concern, affecting millions worldwide. This complex liver disorder ranges from simple steatosis to more severe forms, including metabolic dysfunction-associated steatohepatitis (MASH), which may progress to fibrosis, cirrhosis, and even liver cancer.
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