Analytical Chemistry in Life Sciences - Improving Efficiency & Stability in Biopharma Formulation Development
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Unlocking the analysis of proteins by FTIR spectroscopyUnlocking the analysis of proteins by FTIR spectroscopy

Analysis of proteins — particularly changes to secondary structure following temperature or chemical perturbation — is a now common use case for FTIR spectroscopy. Nonetheless it requires some specific approaches to yield the best results which we explore in this article.

Discover the solutions
 
 
    Improving Efficiency & Stability in Biopharma Formulation DevelopmentImproving Efficiency & Stability in Biopharma Formulation Development
 
Scientists in biopharmaceutical R&D face several challenges, and investing in advanced analytical technologies can help solve them. Specifically, ARGEN helps biopharma teams:
  • Detect biopolymer aggregation and degradation in real time.
  • Determine stability under bioprocessing conditions such as stirring and thermal stress.
  • Identify oligomeric state transitions.
  • Analyze multiple independent samples simultaneously.
  • Determine shelf-life stability for biopolymers at low temperatures.
 
Learn More
 
 
   Innovative Insights into the Interplay Between Proteins and Small MoleculesInnovative Insights into the Interplay Between Proteins and Small Molecules
 
With the support of a Maximizing Investigators' Research Award, or MIRA, from the National Institutes of Health, Michigan State University researcher Aleksandra Skirycz is making fundamental discoveries linked to the health and resilience of plants and animals.
 
   New imaging technique revolutionizes microplastics detection in biological samplesNew imaging technique revolutionizes microplastics detection in biological samples
 
Microplastics, pervasive in both terrestrial and aquatic environments, have been found in diverse organisms, from fish and plants to humans.
 
 MALDI-TOF mass spectrometry proves effective for diagnosing onychomycosis in nail psoriasis
 
MALDI-TOF mass spectrometry proves effective for diagnosing onychomycosis in nail psoriasisNail psoriasis is common in patients with plaque psoriasis and is associated with morbidity, including onychomycosis, which can complicate psoriasis treatments and be difficult to differentiate.
 
 
 Ratiometric fluorescent probes for measuring active albumin in liver disease patients
 
Ratiometric fluorescent probes for measuring active albumin in liver disease patientsAlbumin is a major prognostic factor for patients with advanced liver disease, dependent on its concentration and biological activity.
 
 
 Understanding Algal Gene Expression Through Histone Dynamics
 
Understanding Algal Gene Expression Through Histone DynamicsA previously unknown molecular signature of the regulation of algal genomes during the cell cycle was discovered, thanks to a novel technique that research teams can employ to test and compare various protein forms and protein complexes.
 
 
 Study compares metabolism of humantenirine in human, pig, and goat liver microsomes
 
Study compares metabolism of humantenirine in human, pig, and goat liver microsomesGelsemium elegans Benth (G. elegans) is a traditional medicinal plant; however, it is highly toxic, and toxicity varies significantly between species.
 
 
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