Daily tomatoes lowered a key marker of liver fat in MASLD trial
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 Study links higher body fat to lower sperm counts despite normal BMIStudy links higher body fat to lower sperm counts despite normal BMI
 
Among 1,058 Danish men, higher body fat percentage was associated with lower total sperm count and altered reproductive hormone levels, but not testicular volume. Body fat percentage showed stronger links with several semen measures than BMI or waist-to-height ratio, with the sperm-count association strengthening among men with normal BMI.
 
 
 Daily tomatoes lowered a key marker of liver fat in MASLD trialDaily tomatoes lowered a key marker of liver fat in MASLD trial
 
An exploratory randomized trial found that 200 g of raw tomatoes plus 50 g of tomato sauce daily for six weeks produced a greater reduction in CAP-defined hepatic steatosis than a tomato-free diet in adults with MASLD. The improvement occurred without major weight or metabolic changes, but larger and longer trials are needed to confirm its clinical significance.
 
   Review finds blueberry and grape polyphenols may improve vascular healthReview finds blueberry and grape polyphenols may improve vascular health
 
A review of 37 publications found that grape- and blueberry-derived polyphenols were associated with modest improvements in cardiovascular risk markers, particularly endothelial function. However, most studies were small or short-term, frequently tested concentrated products, and measured biomarkers rather than cardiovascular events.
 
   Gut microbiome shifts may begin before Alzheimer’s symptoms appearGut microbiome shifts may begin before Alzheimer’s symptoms appear
 
A narrative review links reduced SCFA-producing gut bacteria and altered microbial metabolism with Alzheimer’s disease, while early evidence suggests similar changes may appear before cognitive symptoms. Mediterranean, DASH, MIND, and prudent diets are associated with beneficial microbial profiles, but direct evidence connecting diet, the microbiome, and amyloid pathology remains limited.
 
   We underestimate how much personality changes with age, study findsWe underestimate how much personality changes with age, study finds
 
Researchers compared beliefs from 887 US adults with modeled lifespan trajectories from 166,971 participants across eight longitudinal studies. Population-average Big Five traits changed as much as or more than many health, financial, psychological, and social measures, despite people perceiving personality as unusually stable.
 
 Father's diet before conception impacts baby's body composition
 
Father's diet before conception impacts baby's body compositionA father's diet can affect his children's health and body composition before they are even conceived. A study of 43 triads of fathers, mothers, and newborns treated in the public healthcare system of Ribeirão Preto in the state of São Paulo, Brazil, demonstrated this.
 
 
 Parenthood impacts women's health more than men's health
 
Parenthood impacts women's health more than men's healthAccording to OPIK, the research group of the EHU-University of the Basque Country, the arrival of children is associated with changes in women's health that are not observed in men's health.
 
 
 This edible flower could do more than brighten a plate
 
This edible flower could do more than brighten a plateA review of 76 publications finds that pot marigold contains more than 500 reported secondary metabolites, along with natural pigments, antioxidants, and substantial dietary fiber. Early food studies report promising results in yogurt, bread, pasta, and edible oils, but limited product trials and no clinical evidence currently prevent human health claims.
 
 
 Persistent financial hardship tracks with poorer memory and processing speed by midlife
 
Persistent financial hardship tracks with poorer memory and processing speed by midlifeResearchers linked persistent low income and financial hardship across early and mid-adulthood to poorer processing speed and verbal memory at age 53 in a British birth cohort. Neuroimaging suggested greater vulnerability to later brain atrophy among men, people from disadvantaged childhood backgrounds, and APOE-ε4 carriers, although these subgroup findings require replication.
 
 
 Too little or too much iodine may push immunity off balance
 
Too little or too much iodine may push immunity off balanceThis narrative review finds that adequate iodine supports thyroid hormone signaling, leukocyte metabolism, antioxidant defenses, and antimicrobial activity in humans and domesticated mammals. Both deficiency and sustained excess may impair immunity or promote thyroid inflammation, but precise immune-specific intake thresholds remain uncertain.
 
 
 Daytime cortisol patterns track cognitive decline but not Alzheimer’s disease risk
 
Daytime cortisol patterns track cognitive decline but not Alzheimer’s disease riskIn 3,895 older adults, moderate daytime cortisol variability was associated with better cognition and slower decline, while the highest daily cortisol exposure was linked to poorer cognition and faster decline. Cortisol patterns differed between Black and White participants, but their relationships with cognition were similar, and none predicted incident Alzheimer’s disease.
 
 
 UCLA researchers find strategy to improve prostate cancer therapies
 
UCLA researchers find strategy to improve prostate cancer therapiesUCLA researchers have identified a promising strategy to make a new class of targeted cancer therapies more effective against one of the deadliest forms of prostate cancer, potentially overcoming treatment resistance that has limited their success.
 
 
 Body fat percentage predicts male fertility better than BMI
 
Body fat percentage predicts male fertility better than BMIA man's body fat percentage may be a better indicator of his reproductive health than body mass index (BMI) according to a large study of over 1000 Danish men.
 
 
 Deep-Learning Holography Detects Elusive Circulating Tumor Cells in Prostate Cancer
 
Deep-Learning Holography Detects Elusive Circulating Tumor Cells in Prostate CancerResearchers combined microfluidic enrichment, AI-assisted holography, and fluorescence profiling to identify circulating tumor cell candidates in 13 men with metastatic castration-resistant prostate cancer and 8 healthy donors. The platform found higher median candidate counts in patients, while nearly two-thirds of PSMA-positive candidates lacked EpCAM, suggesting EpCAM-dependent assays could miss some cells.
 
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