A pressing need for therapeutics to treat the metabolic disorder Non-alcoholic steatohepatitis (NASH) has led to the development of human liver microphysiological systems (MPS).Explore CN-Bio's MPS’ ability to recapitulate an advanced NASH phenotype (characterized by fibrosis), quantify biomarker expression and assess the efficacy of drugs that entered clinical trials.
Study found that higher soft drink consumption is associated with an increased risk of nonalcoholic fatty liver disease, especially in males, within a cohort of Mexican adults.
Innovative use of lipid nanoparticles to deliver immune agonists shows promise in activating anti-tumor immunity in pancreatic ductal adenocarcinoma models.
Long-term exposure to air pollution and poor lifestyle choices are key contributors to non-alcoholic fatty liver disease (NAFLD), affecting global liver health.
The study investigates the role of autophagy in hepatic progenitor cells (HPCs) and its potential to modulate exosomal microRNAs (miRNAs) to inhibit liver fibrosis in the context of schistosomiasis, a disease caused by parasitic flatworms that can lead to severe organ damage, particularly to the liver.
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