| |  Millions of people worldwide are living with undiagnosed heart rhythm disorders that can lead to stroke, heart failure or sudden cardiac death – often with little or no warning. | |
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| |  A triple-targeted preclinical therapy combining daraxonrasib, afatinib, and SD36 drove durable pancreatic cancer regression by blocking KRAS/RAS, EGFR/HER2, and STAT3 signaling. The approach prevented treatment resistance across mouse and human tumor-derived models, but remains preclinical and requires more clinically suitable drug combinations before human testing. | |
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| |  Most breast cancers are worsened by estrogens. To combat the recurrence of these cancers, clinicians treat patients with inhibitors for estrogen production, like letrozole. But many patients do not adhere to this treatment due to negative side effects. | |
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| |  Women with abnormal mammograms often have to wait for weeks to find out whether they have breast cancer. | |
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| |  Immunotherapies such as so-called checkpoint inhibitors activate the body's own immune system to fight cancer cells and have revolutionized the treatment of many types of tumor. | |
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| |  One of the most widely used chemotherapeutic agents for colorectal cancer is 5-fluorouracil (5-FU), a cornerstone treatment that has improved outcomes for countless patients. | |
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| | Discover how endotoxin-free proteins help minimize hidden experimental risks in cancer and immunology research. | |
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| | Black women experience disproportionately elevated risks of developing and dying from early-onset breast cancer. New research published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society, reveals the genes that are most likely to be mutated to contribute to these increased risks. | |
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| | Obesity may change how early-stage breast cancer becomes invasive, according to a study by University of Oklahoma researchers published in The American Journal of Pathology. | |
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| | X-rays allow professionals to diagnose injuries or ailments and peer inside suitcases at the airport, along with a variety of other applications. | |
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| | Malignant tumors remain a major threat to human health, with conventional therapies and first-generation immune checkpoint inhibitors (ICIs) facing limitations like drug resistance and low response rates. | |
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| | Treating breast cancer remains a major medical challenge worldwide. This is largely due to the ability of breast cancer cells to remain hidden for years before triggering a relapse, which can occur even decades after successful treatment of the primary tumor. | |
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| | Many people with breast cancer can safely avoid chemotherapy with the use of a gene test, potentially sparing them unnecessary side effects without increasing the risk of the cancer returning, a large international clinical trial led by UCL has found. | |
