New discovery reveals crucial link between cholesterol and breast cancer progression

	Breast Cancer
	The latest breast cancer news from News Medical

Cancer Center at Illinois (CCIL) Program Leader Erik Nelson's lab made an important discovery about the relationship between cholesterol and breast cancer progression with crucial implications for breast cancer therapeutics.

			What makes truffles more than a delicacy? They’re packed with bioactive compounds Italian researchers reviewed the chemical composition and biological potential of truffles, identifying them as rich sources of antioxidants, polysaccharides, sterols, and vitamins. The review highlights their promise as functional foods and natural therapeutics, while emphasizing the need for sustainable cultivation and clinical validation.

			Self-guided hypnosis offers safe relief from menopausal hot flashes Can a simple daily audio hypnosis session help women find relief from one of menopause's most disruptive symptoms – hot flashes – without medication? A new clinical trial led by Baylor University's Gary R. Elkins, Ph.D., professor of psychology and neuroscience and director of the Mind-Body Medicine Research Laboratory, suggests it can.

			Long non-coding RNA MALAT1 linked to progression and spread of triple-negative breast cancer When researchers look for potential cancer therapy targets, they typically go after protein-coding genes that participate in disease progression. Disrupt them and negate whatever role they play in cancer's development or spread.

	Innovative research reveals FGD3 as a key player in breast cancer cell death A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the effectiveness of some anticancer agents, including doxorubicin, one of the most widely used chemotherapies, and a preclinical drug known as ErSO, researchers report.

	National initiative helps reduce missed radiation appointments for cancer patients A national quality improvement program led by the American College of Surgeons (ACS) found that transportation barriers and illness are among the top reasons cancer patients miss critical radiation therapy appointments - and that providing hospitals and patients with structured support can reduce missed appointments by up to 40%.

	Green-synthesized nanoparticles enhance cidofovir's anticancer efficacy In this study, led by Nahid Shahabadi from Razi University in Kermanshah, researchers developed an environmentally friendly approach to enhance the performance of cidofovir, a drug used to treat infections caused by DNA viruses. The work responds to the growing need for therapies that are safer, more effective, and better targeted.

	Breast cancer cells use a molecular switch to survive stress Cells are regularly faced with environmental stresses that may damage or destroy them. To survive, they quickly adjust their gene expression to protect themselves.

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