Review explores how generative AI could support precision oncology decision-making
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 AI model flags hidden breast cancers years before diagnosis in routine mammogramsAI model flags hidden breast cancers years before diagnosis in routine mammograms
 
Researchers evaluated four deep learning models using over 112,000 negative screening mammograms from the UK NHS to determine how well artificial intelligence could predict future breast cancers missed during routine screening. The MIT-developed Mirai model performed best, identifying about 27.5% of interval cancers within the top 4% of women flagged as highest risk.
 
 
 Review explores how generative AI could support precision oncology decision-makingReview explores how generative AI could support precision oncology decision-making
 
A narrative review examines how generative AI tools such as large language models and vision-language models could assist precision oncology by interpreting genomic data, matching patients to clinical trials, and synthesizing complex clinical information. The authors emphasize governance, human oversight, and retrieval-based safeguards to ensure these systems are deployed safely in cancer care.
 
   Combined CDK4/6 and EGFR inhibition improves pancreatic cancer therapyCombined CDK4/6 and EGFR inhibition improves pancreatic cancer therapy
 
Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS inactivates RB1 via CDK4/6, while RB1 mutation is rare.
 
   Structured exercise helps chemotherapy patients maintain cognitive function and mental clarityStructured exercise helps chemotherapy patients maintain cognitive function and mental clarity
 
New research in the March 2026 issue of JNCCN-Journal of the National Comprehensive Cancer Network suggests that exercise may help people with cancer stay mentally sharp and better able to handle daily tasks, work, and social activities through chemotherapy treatment delivered on an every two-week cycle.
 
   VALANX Biotech secures €3 million to advance LIV-1 ADC for metastatic triple-negative breast cancerVALANX Biotech secures €3 million to advance LIV-1 ADC for metastatic triple-negative breast cancer
 
VALANX Biotech (VALANX), a biotech company developing a technology for site-selectable, site-specific protein conjugation, today announced it has secured €3 million to advance its lead antibody-drug conjugate (ADC) program.
 
 Fertility treatments linked to small increases in some cancers
 
Fertility treatments linked to small increases in some cancersFindings indicate small increases in certain cancers linked to assisted reproduction, though overall cancer incidence aligns with the general female population.
 
 
 Geographic location strongly influences stage of breast cancer diagnosis
 
Geographic location strongly influences stage of breast cancer diagnosisWhere a woman lives significantly affects whether her breast cancer is diagnosed at an early or late stage, according to a national analysis published in the Journal of the American College of Surgeons (JACS).
 
 
 Study identifies immune cells and RANK protein as fertility regulators
 
Study identifies immune cells and RANK protein as fertility regulatorsThe kick off signal for puberty begins in the brain. Specifically, in the hypothalamus, where specific neurons release a hormone that activates the hypophysis, at the base of the skull, which then releases other hormones to start gonad –ovaries or testicles –maturation.
 
 
 How synthetic ECM hydrogels improve cancer organoid models for drug discovery
 
How synthetic ECM hydrogels improve cancer organoid models for drug discoveryPGmatrix's synthetic extracellular matrices enhance oncology research, offering tunable hydrogels that improve reproducibility in cancer drug discovery.
 
 
 Mechanical forces inside tumors promote breast cancer growth and invasion
 
Mechanical forces inside tumors promote breast cancer growth and invasionA new study led by researchers at Adelaide University and published in Science Advances has revealed why some cancers can grow and survive in the body, while others cannot.
 
 
 Experimental therapy eliminates pancreatic precancerous cells in mice study
 
Experimental therapy eliminates pancreatic precancerous cells in mice studyA new preclinical study in mice shows that precancerous cells in the pancreas can be eliminated before they have the chance to become tumors.
 
 
 Dual-positive hybrid cells linked to shorter survival in advanced breast cancer
 
An enigmatic type of circulating tumor cell called a dual-positive (DP) cell is associated with shorter survival time in patients with advanced breast cancer, according to a study led by investigators at Weill Cornell Medicine and NewYork-Presbyterian.
 
 
 Adelaide University decodes the secrets of cancer survival
 
A new study led by researchers at Adelaide University and published in Science Advances has revealed why some cancers can grow and survive in the body, while others cannot.
 
 
 Researchers achieve breakthrough in the production of vital chemotherapy agent
 
An international team of researchers has achieved a breakthrough in the production of doxorubicin, a vital chemotherapy agent.
 
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