Obscure X chromosome protein emerges as key driver in several cancers

	Breast Cancer
	The latest breast cancer news from News Medical

	Obscure X chromosome protein emerges as key driver in several cancers A little-known protein encoded on the X chromosome is attracting growing attention for its potential role in cancer development and treatment.

	Cannabis compounds may weaken glioblastoma response to chemotherapy and radiation Several cannabinoids reduced chemotherapy- and radiation-induced apoptosis in glioblastoma cell models, with effects linked to reduced apoptotic priming, increased pro-survival signaling, and G1 cell-cycle arrest. The findings raise concern that cannabinoid exposure could interfere with some cancer treatments, although the results are limited to laboratory models and require in vivo and clinical validation.

			Genetic tool turns soft cancer cells into immune targets Researchers at the USC Viterbi School of Engineering and Keck School of Medicine of USC have engineered a remarkable genetic tool that addresses one of the most persistent obstacles in cancer immunotherapy: the physical softness of tumors.

			Novel drug puts cancer cells under extreme metabolic stress Cancer cells have a voracious appetite for sugar-using it to fuel their rapid growth. This is why many scientists have tried to develop drugs that block cancer cells' metabolism by cutting off their sugar supply.

			Digital care app improves quality of life for breast cancer patients Regularly checking in with patients with metastatic breast cancer by way of an app to enquire about their well-being – and responding promptly – can alleviate their debilitating fatigue and make their daily lives easier.

	Lab-grown mini tumors help scientists predict breast cancer treatment success Researchers at UC San Francisco have developed a new method to predict how different types of breast cancer will respond to treatment, using patient data from the I-SPY2 breast cancer trial and rapid testing on lab-grown mini tumors.

	Mitochondrial gene RTN4IP1 drives triple-negative breast cancer metastasis Triple-negative breast cancer accounts for approximately 15% of all breast cancer cases. It is characterized by the absence of estrogen receptor, progesterone receptor, and HER2 expression, rendering it insensitive to conventional endocrine and targeted therapies.

	New program receives CDC grant to expand access to breast and cervical cancer screening The Louisiana Breast and Cervical Health Program (LBCHP), a program of the LSU LCMC Health Cancer Center and housed at the LSU Health New Orleans School of Public Health, has received more than $3 million from the Centers for Disease Control and Prevention to expand access to breast and cervical cancer screening, diagnostic services and patient navigation across Louisiana.

	Two-gene interaction reveals metastatic risk in breast cancer Why do some breast cancer patients face a much higher risk of distant metastasis, while others with seemingly similar disease experience far better outcomes?

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