Landmark study maps mutational landscape of triple-negative breast cancer in African American women

	Breast Cancer
	The latest breast cancer news from News Medical

	Landmark study maps mutational landscape of triple-negative breast cancer in African American women Triple-negative breast cancer (TNBC), the deadliest breast cancer subtype, disproportionately affects African American women – but until now, they were underrepresented in genomic studies aimed at identifying the genetic mutations driving the disease.

	Dormant tumor cells targeted to reduce breast cancer relapse A first-of-its-kind, federally funded clinical trial has shown it's possible to identify breast cancer survivors who are at higher risk of their cancer coming back due to the presence of dormant cancer cells and to effectively treat these cells with repurposed, existing drugs.

			Study finds minimal risk of second cancer in breast cancer survivors For women diagnosed with early breast cancer, the long-term risk of developing a second primary cancer is low (around 2-3% greater than women in the general population), finds a study published by The BMJ today.

			Breast cancer cells hijack iron-handling macrophages to promote bone metastasis and anemia Breast cancers frequently spread to the bone, establishing tumors that are largely impervious to treatment and are associated with poor patient prognoses.

			Study brings hope for a more personalized approach to treat ER+ breast cancer A new study from researchers at Baylor College of Medicine brings hope for a more personalized approach to treat estrogen receptor-positive (ER+) breast cancer, the most common type of this cancer.

	Gene expression maps explain why diseases often occur together This study reveals how gene expression patterns uncover molecular pathways linking comorbidities, enhancing treatment strategies for overlapping diseases.

	Researchers identify genetic toolkit to reprogram cells into immune sentinels An international team led by researchers at Lund University in Sweden has identified the molecular tools needed to reprogram ordinary cells into specialized immune cells.

	Researchers reveal how diseases interact at the genetic level Researchers reveal how diseases interact at the genetic level

	AACR 2024 spotlight on antibody-drug conjugate advancements Discover the latest advancements in antibody-drug conjugates presented at AACR 2024, including novel targets and combination therapy breakthroughs.

	Study urges significant investment in cancer research in poorer nations Researchers at the University of Southampton, examining worldwide variations in funding for cancer research, say there's a pressing need to invest more in lower-income countries.

	Sugar-coated nanoparticles offer new hope for treating triple-negative breast cancer Triple-negative breast cancer is particularly aggressive and difficult to treat; but recent research may offer a new way to target the often-deadly disease.

	Proteomic study reveals new drug targets in gastric signet ring cell carcinoma Gastric signet ring cell carcinoma (GSRCC) is a distinct subtype of gastric cancer (GC) with unique epidemiological and pathogenic characteristics.

	HER2 and CD24 emerge as promising radiotheranostic targets in endometrial cancer Two molecular targets-human epidermal growth factor 2 (HER2) and cluster of differentiation 24 (CD24)-are highly promising candidates for new nuclear diagnostics and therapeutics for endometrial cancer, according to new research published in The Journal of Nuclear Medicine.

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