Thymulin curbs age-related inflammation and slows breast tumors in mice
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 AI model predicts cancer diagnoses up to a year in advance using routine clinical dataAI model predicts cancer diagnoses up to a year in advance using routine clinical data
 
Researchers developed Oncoformer, a multimodal transformer that analyzes longitudinal health records and chest X-rays to classify cancer, predict diagnoses up to one year in advance, infer tumor stage, and forecast treatment response and recurrence risk. Validation across large independent cohorts showed strong performance, although prospective trials in diverse, average-risk populations are needed before clinical use.
 
 
 Thymulin curbs age-related inflammation and slows breast tumors in miceThymulin curbs age-related inflammation and slows breast tumors in mice
 
Thymulin reduced age-associated inflammatory myeloid cells and slowed breast-tumor growth in aged mice by suppressing NF-κB signaling. The peptide also restored anti-PD-L1 responsiveness in aged mouse models, while human cell and tumor data supported an age-linked inflammatory myeloid profile.
 
   Scientists map protective cell networks hiding dormant breast tumor cellsScientists map protective cell networks hiding dormant breast tumor cells
 
Researchers at the MRC Laboratory of Medical Sciences (LMS), Imperial College London and UCL Genetics Institute have created a detailed map of cells within breast tumors and identified distinct neighborhoods of proliferating and dormant cells.
 
   Robotic microsurgery emerges as central focus in reconstructive surgery researchRobotic microsurgery emerges as central focus in reconstructive surgery research
 
A comprehensive analysis of 484 studies on robot-assisted surgery highlights publication trends, collaboration patterns, and thematic shifts in plastic surgery.
 
 Dual immunotherapy with neoadjuvant chemotherapy shows encouraging activity in ERBB2-negative breast cancer
 
Dual immunotherapy with neoadjuvant chemotherapy shows encouraging activity in ERBB2-negative breast cancerA combination of two immunotherapy drugs showed encouraging activity when added to standard chemotherapy given prior to surgery for patients with high-risk, early-stage HER2-negative breast cancer, according to phase 2 clinical trial results from the ongoing I-SPY2 clinical trial platform.
 
 
 Low-fat diet lowers dietary glycation compounds for years in postmenopausal women
 
Low-fat diet lowers dietary glycation compounds for years in postmenopausal womenResearchers analyzing dietary data from 40,209 postmenopausal women found that a low-fat pattern emphasizing fruits, vegetables, and grains was associated with sustained reductions in estimated dietary advanced glycation end-product intake over approximately seven years.
 
 
 Taiwan Biobank data reveals ongoing natural selection in living humans
 
Taiwan Biobank data reveals ongoing natural selection in living humansFor more than a century, scientists have sought to reconstruct human evolution using diverse lines of evidence, including fossils, genetic variation across populations, and ancient DNA.
 
 
 New cancer vaccine harnesses COVID-19 immune memory to fight tumors
 
New cancer vaccine harnesses COVID-19 immune memory to fight tumorsIn a discovery that could redefine the future of cancer immunotherapy, scientists from Celloram Inc., University Hospitals and Case Western Reserve University have developed a novel cancer vaccine platform that transforms the impact of the largest immunological event in modern history – a synchronized mass immune memory generated through SARS-CoV-2 infection and vaccination – into a powerful ally against cancer.
 
 
 NIH funds research to explore the role of thymulin in inflammaging and cancer
 
As we age, chronic inflammation-or "inflammaging"-increases throughout the body and weakens our ability to fight cancer.
 
 
 Novel dendritic cell vaccine redirects viral memory to fight tumors
 
Novel dendritic cell vaccine redirects viral memory to fight tumorsIn a discovery that could redefine the future of cancer immunotherapy, scientists from Celloram Inc., University Hospitals and Case Western Reserve University have developed a novel cancer vaccine platform that transforms the impact of the largest immunological event in modern history
 
 
 How AI predicts molecular biomarkers from H&E slides
 
How AI predicts molecular biomarkers from H&E slidesAI advancements in digital pathology enable the prediction of molecular biomarkers from routine H&E slides, transforming histopathology and treatment response.
 
 
 Current NICE criteria miss most younger women at breast cancer risk
 
The National Institute for Health and Care Excellence (NICE) criteria used to decide who should be referred by GPs for further breast cancer risk assessment and specialist care misses up to 95% of women under 50 who will go on to develop the disease in the next 10 years, new research by researchers at the University of Cambridge and The Institute of Cancer Research, London, has found.
 
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