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New study challenges the traditional view of gene switches

Some sequences in the genome cause genes to be switched on or off. Until now, each of these gene switches, or so-called enhancers, was thought to have its own place on the DNA.

22 Nov 2024

Pioneering protocol sheds light on NMDA receptor distribution in Alzheimer's brains

Researchers from the Institute for Neurosciences (IN), a joint center of the Miguel Hernández University of Elche (UMH) and the Spanish National Research Council (CSIC), who are also part of the Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED) and the Alicante Institute for Health and Biomedical Research (ISABIAL), have developed a cellular fractionation protocol.

22 Nov 2024

Barcelona launches world’s first joint program on evolutionary medical genomics

Three research institutions in Barcelona have teamed up to launch the world's first Joint Program on Evolutionary Medical Genomics.

22 Nov 2024

Study reveals how brainstem neurons control eye movements

Working with week-old zebrafish larva, researchers at Weill Cornell Medicine and colleagues decoded how the connections formed by a network of neurons in the brainstem guide the fishes' gaze.

22 Nov 2024

Penn engineers cook up a new way for safer, more effective mRNA therapies

Penn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal "recipe" for ionizable lipids -; key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 vaccines and other innovative therapies.

22 Nov 2024

Researchers discover key protein interaction driving skin cancer growth

LMU researchers have discovered how the interplay between a key protein and an endolysosomal ion channel promotes tumor development in skin cancer.

22 Nov 2024

AI may help simplify science communication and restore trust

Have you ever read about a scientific discovery and felt like it was written in a foreign language? If you're like most Americans, new scientific information can prove challenging to understand -; especially if you try to tackle a science article in a research journal.

22 Nov 2024

Parkinson's disease drug disrupts the gut microbiome by inducing iron deficiency

In a groundbreaking new study, conducted within the framework of the FWF-funded Cluster of Excellence "Microbiomes drive Planetary Health", scientists from the University of Vienna, in collaboration with the University of Southampton, Aalborg University and Boston University, have revealed that the widely prescribed Parkinson's disease drug entacapone significantly disrupts the human gut microbiome by inducing iron deficiency.

22 Nov 2024

More than 100,000 young people in the US live with inflammatory bowel disease

The prevalence of inflammatory bowel disease in U.S. children under 20 is increasing, with over 100,000 affected, revealing critical public health concerns.

22 Nov 2024

Anxiety and negative emotions reduced by brain circuit that consciously slows breathing

Findings on the dACC→PnC circuit show how breathing patterns influence anxiety, paving the way for new therapeutic approaches to emotional regulation.

22 Nov 2024

New technology enables rapid detection of TNT metabolites in the human body

Recently, a research group led by Prof. HUANG Chaoqun from the Hefei lnstitutes of Physical Science of the Chinese Academy of Sciences, developed an innovative dual drift tube ion mobility spectrometry (DDT-IMS) technology.

22 Nov 2024

Do podcasts influence health behaviors?

Researchers examine the impact of podcasts on health behaviors and outcomes, use patterns, and individual perceptions.

22 Nov 2024

New study unveils why glioblastoma becomes resistant to treatment

A new study from scientists at the UCLA Health Jonsson Comprehensive Cancer Center helps explain why glioblastoma, one of the most aggressive forms of brain cancer, becomes resistant to treatment, and introduces a new approach that paves the way for more personalized treatment strategies for patients with this deadly brain tumor.

22 Nov 2024

Researchers develop efficient approach for designing custom proteins

Protein design aims to create customized antibodies for therapies, biosensors for diagnostics, or enzymes for chemical reactions.

22 Nov 2024

Short-term menopausal hormone therapy shows no long-term cognitive effects

Short-term menopausal hormone therapy (MHT) did not have long-term cognitive effects when given to women in early postmenopause, according to a study published November 21st in the open-access journal PLOS Medicine by Carey Gleason from the University of Wisconsin-Madison, USA, and colleagues.

22 Nov 2024

Preterm birth linked to increased mortality risk from infancy to adulthood

Findings indicate preterm birth is associated with elevated mortality risks, especially in early years, influenced by gestational age and health factors.

22 Nov 2024

Fermented kimchi may help combat obesity by regulating gut microbiota

Kimchi consumption significantly reduces body fat and enhances metabolic indicators in overweight individuals, highlighting its role in obesity management.

22 Nov 2024

Mapping human biology: Human Cell Atlas leads a new era in precision medicine

The Human Cell Atlas project maps human cells to understand biology, address global health disparities, and advance personalized medicine through ethical and inclusive research practices.

21 Nov 2024

SCimilarity revolutionizes single-cell data analysis with rapid cross-tissue comparisons

Researchers developed SCimilarity, a groundbreaking metric-learning framework, to rapidly analyze and compare single-cell data across tissues, diseases, and experimental conditions. This tool enables scalable discovery of shared cellular states and biological insights across the Human Cell Atlas.

21 Nov 2024

AI models redefine TIL scoring in breast cancer but face challenges in real-world validation

AI models analyzing tumor-infiltrating lymphocytes show promise in predicting outcomes for triple-negative breast cancer, but external validation reveals critical performance gaps.

21 Nov 2024