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Immune cells play a bigger role in high blood pressure than previously thought, opening doors for new treatments

A review in Nature Reviews Nephrology presents the association between immune cells and the development of hypertension, suggesting potential new therapeutic targets to mitigate the disease by managing inflammation.

26 Apr 2024

Scientists identify signaling pathway in liver cells linked to fibrosis

A healthy liver filters all the blood in your body, breaks down toxins and digests fats. It produces collagen to repair damaged cells when the liver is injured.

25 Apr 2024

New research lays foundation for targeted therapies to inhibit NF-κB activation

A new paper by Dana-Farber Cancer Institute scientists lays the foundation for targeted therapies to inhibit activation of nuclear factor kappa B (NF-κB), a transcription factor that plays a role in various autoimmune and inflammatory diseases and cancers.

25 Apr 2024

Researchers uncover mechanism behind mitochondrial dysfunction in Alzheimer's

A team of researchers at Johannes Gutenberg University Mainz (JGU) has identified a mechanism that causes mitochondrial dysfunction in Alzheimer's patients resulting in a reduction of the supply of energy to the brain.

25 Apr 2024

Yeast study reveals evolutionary history of iron uptake mechanisms

Competition and cooperation are fundamental forces that govern the evolutionary and ecological dynamics among species.

25 Apr 2024

Genetically modified mice reveal key players in immune defense against viruses

Chemokines are signaling proteins that orchestrate the interaction of immune cells against pathogens and tumors.

25 Apr 2024

Insilico Medicine's AI-designed drug ISM3412 receives FDA IND approval

Clinical stage artificial intelligence (AI)-driven drug discovery company Insilico Medicine announces that it has received approval from the U.S. Food and Drug Administration for its Investigational New Drug application for ISM3412, a small molecule inhibitor of MAT2A for the potential treatment of MTAP deleted cancers designed with Insilico's generative AI platform.

25 Apr 2024

Multi-omics approach powers Karolinska Institutet's Single Cell Atlas

Researchers at Karolinska Institutet have developed a web-based platform that offers an unprecedented view of the human body at the cellular level.

25 Apr 2024

Putting genomic surveillance of pathogens at the forefront of future pandemic preparedness

The Covid-19 pandemic turned the world upside down. In fighting it, one of our most important weapons was genomic surveillance, based on whole genome sequencing, which collects all the genetic data of a given microorganism.

25 Apr 2024

Genetics studies have a diversity problem that researchers struggle to fix

When he recently walked into the dental clinic at the Medical University of South Carolina donning a bright-blue pullover with "In Our DNA SC" embroidered prominently on the front, Lee Moultrie said, two Black women stopped him to ask questions.

25 Apr 2024

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

25 Apr 2024

Prostaglandin E2: The culprit behind tumor immune evasion

Tumors actively prevent the formation of immune responses by so-called cytotoxic T cells, which are essential in combating cancer. Researchers at the Technical University of Munich (TUM) and the Ludwig-Maximilians-Universität München (LMU) Hospital have now uncovered for the first time how this exactly happens.

24 Apr 2024

Novel lab-grown mini-colons can accurately mimic the development of colorectal tumors

In a breakthrough for cancer research, scientists at EPFL have created lab-grown mini-colons that can accurately mimic the development of colorectal tumors, offering a powerful new tool for studying and testing treatments for the disease.

24 Apr 2024

Giant virus takes down deadly brain parasite

The single-celled organism Naegleria fowleri ranks among the deadliest human parasites. Researchers around Matthias Horn and Patrick Arthofer from the Center for Microbiology and Environmental Systems Science at the University of Vienna, in an international collaboration, have discovered viruses that infect this harmful microbe.

24 Apr 2024

Research links Y chromosome decline to patrilineal societies

The emergence in the Neolithic of patrilineal social systems, in which children are affiliated with their father's lineage, may explain a spectacular decline in the genetic diversity of the Y chromosome observed worldwide between 3,000 and 5,000 years ago.

24 Apr 2024

MSU team creates a promising vaccine candidate for antibiotic-resistant bacteria

Driven by the overuse of antimicrobials, pathogens are quickly building up resistances to once-successful treatments.

24 Apr 2024

Timelapse breakthrough: Scientists capture secrets of early embryonic cell division

The beginning of life is shrouded in mystery. While the intricate dynamics of mitosis is well-studied in the so-called somatic cells – the cells that have a specialized function, like skin and muscle cells – they remain elusive in the first cells of our bodies, the embryonic cells.

24 Apr 2024

New technique allows scientists to study the fatty contents of cancer cells

Imagine being able to look inside a single cancer cell and see how it communicates with its neighbors.

23 Apr 2024

Neurons re-entering cell cycle succumb to senescence in neurodegenerative diseases

Post-mitotic neurons in the brain that re-enter the cell cycle quickly succumb to senescence, and this re-entry is more common in Alzheimer's disease, according to a new study published April 9th in the open-access journal PLOS Biology by Kim Hai-Man Chow and colleagues at the Chinese University of Hong Kong.

23 Apr 2024

U-M scientists develop new tool to better understand neuronal signaling

University of Michigan researchers have developed a new tool to better understand how chemicals like dopamine and epinephrine interact with neurons.

23 Apr 2024

Life Science News

Immune cells play a bigger role in high blood pressure than previously thought, opening doors for new treatments

Scientists identify signaling pathway in liver cells linked to fibrosis

New research lays foundation for targeted therapies to inhibit NF-κB activation

Researchers uncover mechanism behind mitochondrial dysfunction in Alzheimer's

Yeast study reveals evolutionary history of iron uptake mechanisms

Genetically modified mice reveal key players in immune defense against viruses

Insilico Medicine's AI-designed drug ISM3412 receives FDA IND approval

Multi-omics approach powers Karolinska Institutet's Single Cell Atlas

Putting genomic surveillance of pathogens at the forefront of future pandemic preparedness

Genetics studies have a diversity problem that researchers struggle to fix

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Prostaglandin E2: The culprit behind tumor immune evasion

Novel lab-grown mini-colons can accurately mimic the development of colorectal tumors

Giant virus takes down deadly brain parasite

Research links Y chromosome decline to patrilineal societies

MSU team creates a promising vaccine candidate for antibiotic-resistant bacteria

Timelapse breakthrough: Scientists capture secrets of early embryonic cell division

New technique allows scientists to study the fatty contents of cancer cells

Neurons re-entering cell cycle succumb to senescence in neurodegenerative diseases

U-M scientists develop new tool to better understand neuronal signaling

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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