Disease/Infection News

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New data highlights spread of carbapenem-resistant infections in Europe

Patients seeking treatment in hospital or other healthcare facilities can be particularly vulnerable for infections they acquire during their stay, especially if the infections are difficult to treat because they are resistant to commonly used drugs.

22 Nov 2024

Wayne State's CEID calls for immediate community action on antimicrobial resistance

Wayne State University's Center for Emerging and Infectious Diseases (CEID) is launching its participation in World AMR Awareness Week with an urgent message: the growing threat of antimicrobial resistance requires immediate community action, so it is critical to educate, advocate, and act now.

22 Nov 2024

Advanced diagnostic kit developed for detecting highly pathogenic H5N1 avian influenza virus

The Diagnostics Development Hub (DxD Hub), a national platform hosted by the Agency for Science, Technology and Research (A*STAR), Singapore, in collaboration with the National Institute for Environmental Studies (NIES), Japan, and the A*STAR Bioinformatics Institute (A*STAR BII), has successfully developed Steadfast, an advanced diagnostic kit for detecting the highly pathogenic H5N1 Avian Influenza Virus (AIV).

22 Nov 2024

AI can help tackle urinary tract infections and antimicrobial resistance

New research from the Centres for Antimicrobial Optimisation Network (CAMO-Net) at the University of Liverpool has shown that using artificial intelligence (AI) can improve how we treat urinary tract infections (UTIs), and help to address antimicrobial resistance (AMR).

22 Nov 2024

Breakthrough discovery could lead to novel malaria vaccines and therapies

Malaria, particularly in its severe forms, remains a global health and economic burden. It causes the deaths of more than 600,000 people every year – most of them African children under five.

21 Nov 2024

Small brain-penetrating molecule offers hope for treating aggressive brain tumors

Gliocidin selectively kills glioblastoma cells by inhibiting nucleotide synthesis, showing potential as a therapeutic option in combination with temozolomide.

21 Nov 2024

Modified darobactin offers hope for combatting antibiotic-resistant bacteria

Antibacterial drugs are important for treating infections. But increasingly, bacterial resistance to current drugs -; so they don't work well, or even at all -; means new ones are urgently needed.

21 Nov 2024

Study projects global antibiotic use to rise by over 50% by 2030

A study reveals a 20.9% rise in global antibiotic use from 2016 to 2023, with middle-income countries leading the increase and highlighting resistance issues.

21 Nov 2024

Cigarette smoke can induce disordered oropharyngeal microbiota that aggravates flu severity

New research has shown that cigarette smoke can induce disordered oropharyngeal microbiota that aggravates the severity of influenza A virus infection.

20 Nov 2024

Researchers uncover hidden roles of accessory genes in SARS-CoV-2

Viruses are lean, mean, infection machines. Their genomes are tiny, usually limited to a handful of absolutely essential genes, and they shed extra genomic deadweight extremely fast.

20 Nov 2024

New approach to stabilize RSV protein could lead to better vaccines

In most people, the lung-infecting pathogens known as respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) trigger mild cold-like symptoms. But in infants and seniors, these viruses can cause severe pneumonia and even death.

20 Nov 2024

Antiseizure medications in pregnancy tied to child neurodevelopment risks

Researchers investigate how anti-seizure medication use during pregnancy may increase the risk of neuropsychological conditions in children.

20 Nov 2024

SARS-CoV-2 hijacks cholesterol trafficking to fuel infection and evade immune responses

SARS-CoV-2 disrupts cholesterol metabolism by using its ORF3a protein to sequester cholesterol in lysosomes, reducing BMP levels and optimizing viral survival. This novel mechanism offers insights into long-term metabolic complications of COVID-19.

19 Nov 2024

WHO grants Emergency Use Listing for LC16m8 mpox vaccine

The World Health Organization (WHO) has granted Emergency Use Listing (EUL) for the LC16m8 mpox vaccine, making it the second mpox vaccine to be supported by WHO following the Director-General's declaration of an mpox public health emergency of international concern (PHEIC) on 14 August 2024.

19 Nov 2024

Urgent action needed to combat AMR and achieve EU's 2030 targets

Between 2019 and 2023, antibiotic consumption in the EU increased by 1%, moving further away from the 2030 target of a 20% reduction recommended by the Council of the European Union.

19 Nov 2024

Study investigates impact of oxygen therapy on oxidative stress in patients with COVID-19 pneumonia

Severe COVID-19 pneumonia often requires high concentrations of oxygen, which can potentially lead to oxidative stress and lung injury.

19 Nov 2024

Study provides insights into trends and disparities of neonatal infectious diseases in LMICs

Researchers from Peking University have conducted an in-depth study on the epidemic status, secular trends, and risk factors of 15 common neonatal infectious diseases across low- and middle-income countries (LMICs) from 1990 to 2019.

19 Nov 2024

Malaria crystal structure offers clues for more effective medications

Prof. Leslie Leiserowitz first became intrigued by malaria when he was a young boy in South Africa. His father, who scouted the continent in search of wood for the family business, brought back not only tales of elephants and gorillas but also skin rashes and ringing in his ears, side effects of the quinine he took to prevent malaria.

19 Nov 2024

New nasal vaccine could help stop the spread of whooping cough

As whooping cough cases rise in the U.S., a new nasal vaccine developed by Tulane University may hold the key to reducing the spread of the highly contagious respiratory disease.

19 Nov 2024

Rising temperatures fuel global spread of dengue infections

Climate change is having a massive global impact on dengue transmission, accounting for 19% of the current dengue burden, with a potential to spark an additional 40%-60% spike by 2050 -; and by as much as 150%-200% in some areas -; according to a new study presented today at the Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH).

18 Nov 2024