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Racial and ethnic minorities, women, and the elderly were less likely to enroll in cancer clinical trials than whites, men, and younger patients

According to background information provided by the authors, "Ten years have passed since Congress responded to concerns about unequal access to clinical trials and enacted the National Institutes of Health (NIH) Revitalization Act, which encouraged representation of women and minority patients in NIH-sponsored research.

14 Jun 2004

Research shows there is no substitute for reliable birth control

US research published (Thursday 10 June) in Europe's leading reproductive medicine journal Human Reproduction suggests that a single act of unprotected intercourse is more likely to lead to an unwanted pregnancy than was previously believed.

12 Jun 2004

Cannabis extract drug may help patients with rheumatoid arthritis

The multi centre double blind, randomised, parallel group study in 58 patients assessed the efficacy, safety and tolerability of Sativex®, a whole plant medicinal cannabis extract, compared with placebo for the treatment of pain caused by Rheumatoid Arthritis. Study medication was administered by means of a spray into the mouth as an evening dose only and measures were assessed the following day.

11 Jun 2004

New treatment significantly improves long-term outlook for breast cancer survivors

An updated analysis from an international clinical trial of the drug letrozole was presented on June 8, 2004 at the American Society of Clinical Oncology annual meeting in New Orleans.

11 Jun 2004

Drug commonly used for diabetes might be effective in treating multiple sclerosis

Researchers at the University of Illinois at Chicago are launching a clinical trial to determine whether a drug commonly used for diabetes might be effective in treating multiple sclerosis, an autoimmune disease that affects 350,000 Americans.

10 Jun 2004

Drug may benefit patients suffering deep scarring after radiation treatment

Cancer patients who suffer from a progressive, deep scarring of tissue following radiation treatment might benefit from a drug that’s FDA-approved to treat vascular disease, according to a University of Rochester study published in this month’s Journal of Clinical Oncology.

10 Jun 2004

Non-aspirin pain drugs may help men with recurrent prostate cancer

Early results from a University of North Carolina at Chapel Hill School of Medicine study may determine if drugs called Cox-2 inhibitors, a newer type of non-aspirin pain medicine now widely prescribed for arthritis symptoms, may benefit men with recurrent prostate cancer.

10 Jun 2004

SU11248 proves effective in the treatment of gastrointestinal stromal tumors

A drug originally developed to block the formation of blood vessels in tumors has been shown to overcome resistance to treatment with Gleevec in patients with gastrointestinal stromal tumors (GIST).

9 Jun 2004

Chemotherapy regimen more effective and more toxic in Japanese patients than in American patients

A chemotherapy regimen commonly used to treat non-small cell lung cancer is both more effective and more toxic in Japanese patients than in American patients, researchers reported Saturday at the annual meeting of the American Society of Clinical Oncologists.

7 Jun 2004

A biological agent used without chemotherapy appears to offer a disease-free future to patients with rare leukemia

A biological agent — a drug that wraps vitamin A inside bubbles of fat — used without chemotherapy appears to offer as many as one-third of patients with a rare form of leukemia an opportunity for a long-term, disease-free future, say researchers at The University of Texas M. D. Anderson Cancer Center.

7 Jun 2004

Experimental human monoclonal antibody shows striking benefit in patients with advanced melanoma

Early testing of an experimental human monoclonal antibody showed a striking benefit in patients with advanced melanoma, say researchers at The University of Texas M. D. Anderson Cancer Center, who presented their findings at the annual meeting of the American Society of Clinical Oncology.

7 Jun 2004

Investigational drug, LAF237 improved glycemic control in patients with type 2 diabetes

Research presented today showed that the investigational drug, LAF237, the first in a new class, improved glycemic control in patients with type 2 diabetes. In this study, LAF237, which is administered as a tablet to be taken orally, was added to the standard diabetes treatment metformin in patients whose diabetes was not adequately controlled by metformin alone.

7 Jun 2004

Combination treatment may help type 2 diabetes patients

New research presented by Peter Weissman, M.D., from the University of Miami, at the 64th Annual Scientific Sessions of the American Diabetes Association shows that combination treatment with rosiglitazone maleate and metformin significantly improves certain markers of cardiovascular disease risk in patients with type 2 diabetes compared to metformin alone.

6 Jun 2004

Velcade major improvement over standard therapy for relapsed multiple myeloma

Early results from a major, international Phase III clinical trial decisively show that recurrent multiple myeloma is more effectively treated with the drug bortezomib (trade name: Velcade TM) than with dexamethasone, a drug that for decades has been the standard therapy for relapsed disease, researchers at Dana-Farber Cancer Institute report.

6 Jun 2004

Overweight families unaware & unconcerned about risk of diabetes and premature heart disease

Two new studies show that many children are at high risk for diabetes and premature heart disease, according to British and U.S. reports here today at the American Diabetes Association's 64th Annual Scientific Sessions.

5 Jun 2004

Vitamin C can increase the severity of spontaneous knee osteoarthritis

High doses of vitamin C increase the severity of spontaneous knee osteoarthritis in an animal model of the disease, according to a new study by Duke University Medical Center researchers.

5 Jun 2004

Polycystic ovary syndrome more common than originally thought

Researchers at Cedars-Sinai Medical Center and the University of Alabama, Birmingham, have found that a complex hormonal disorder affecting the reproductive and metabolic function of premenopausal women may be considerably more common in the United States than previously believed from earlier, smaller studies.

5 Jun 2004

Parents oblivious to their children's weight problems

5 Jun 2004

Breakthrough in gene therapy

Despite a roller-coaster ride of ups and downs during the past 15 years, gene therapy has continued to attract many of the world's brightest scientists. They are tantalized by the enormous potential that replacing missing genes or disabling defective ones offers for curing diseases of many kinds.

3 Jun 2004

Chromium picolinate supplementation reduced carbohydrate cravings and atypical depression

Results of a new double-blind, placebo-controlled human clinical trial found that daily supplementation with chromium picolinate significantly reduced some key symptoms of atypical depression.

2 Jun 2004

Clinical Trial News and Research

Racial and ethnic minorities, women, and the elderly were less likely to enroll in cancer clinical trials than whites, men, and younger patients

Research shows there is no substitute for reliable birth control

Cannabis extract drug may help patients with rheumatoid arthritis

New treatment significantly improves long-term outlook for breast cancer survivors

Drug commonly used for diabetes might be effective in treating multiple sclerosis

Drug may benefit patients suffering deep scarring after radiation treatment

Non-aspirin pain drugs may help men with recurrent prostate cancer

SU11248 proves effective in the treatment of gastrointestinal stromal tumors

Chemotherapy regimen more effective and more toxic in Japanese patients than in American patients

A biological agent used without chemotherapy appears to offer a disease-free future to patients with rare leukemia

Experimental human monoclonal antibody shows striking benefit in patients with advanced melanoma

Investigational drug, LAF237 improved glycemic control in patients with type 2 diabetes

Combination treatment may help type 2 diabetes patients

Velcade major improvement over standard therapy for relapsed multiple myeloma

Overweight families unaware & unconcerned about risk of diabetes and premature heart disease

Vitamin C can increase the severity of spontaneous knee osteoarthritis

Polycystic ovary syndrome more common than originally thought

Parents oblivious to their children's weight problems

Breakthrough in gene therapy

Chromium picolinate supplementation reduced carbohydrate cravings and atypical depression

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