Cytokine News and Research

RSS

Drug trial fiasco induced immune system overload in patients

The doctors who treated six British men in a trial of a drug in March which went horribly wrong, say they believe the men suffered an immune system overreaction known as a cytokine storm.

15 Aug 2006

Reduced levels of antiinflammatory cytokines in patients with chronic widespread pain

Chronic widespread pain, a common medical condition, can be difficult to treat and is often associated with fatigue, poor sleep and depression.

26 Jul 2006

NICE backs use of Enbrel and Raptiva to treat severe psoriasis

NICE has today issued guidance for the use of the targeted biological therapies, Enbrel (etanercept) and Raptiva (efalizumab), to treat adult patients with severe plaque psoriasis.

26 Jul 2006

Scientists identify overactive protein that plays a key role in cystic fibrosis

A team led by Johns Hopkins Children's Center scientists has identified and successfully tamed an overactive protein that plays a key role in cystic fibrosis (CF), a genetic disorder that interferes with the body's ability to transport chloride in and out of cells.

5 Jul 2006

Scientists find a cytokine against auto-immune hepatitis

There are about 400 million patients of hepatitis in the world. Some of them are suffering from autoimmune hepatitis, a disease in which the body's immune system attacks liver cells.

5 Jul 2006

Nventa granted European patent covering heat shock protein fusion to treat influenza

Nventa Biopharmaceuticals Corporation announced that the European Patent Office has granted Patent Number EP 941,315 to Nventa.

8 Jun 2006

Sunitinib shows promise in treating metastatic renal cell cancer

A new study suggests that sunitinib is a promising agent for treatment of metastatic renal cell cancer, currently a disease without highly effective treatment options, according to an article in the June 7 issue of the Journal of the American Medical Association.

7 Jun 2006

Sunitinib malate drug shows significant benefits over standard treatment for advanced kidney cancer

According to a new study, the drug sunitinib malate (Sutent.) is more effective than the current standard cytokine treatment given as an initial therapy for patients with advanced kidney cancer, also known as metastatic renal cell carcinoma (mRCC).

5 Jun 2006

c-myc gene found to play role in immune system

c-myc, a gene commonly involved in cancer onset, has been found to have a role in the immune system's normal function according to a study published in Blood.

11 May 2006

Interferon-gamma plays a critical role in damaging the cells that produce myelin

A new way to preserve the cells that surround and protect nerves could lead to new treatments for demyelinating diseases such a multiple sclerosis, a research team reports in the May 10, 2006, issue of the Journal of Neuroscience.

10 May 2006

Renewed interest in studying influenza A viruses

The emergence of the avian influenza virus H5N1 that is currently devastating chicken flocks in many countries and threatening to unleash a worldwide epidemic among humans has triggered a renewed interest among scientists in studying influenza A viruses, according to investigators at St. Jude Children's Research Hospital.

9 May 2006

Circulating tumor cells in the bone marrow of patients with metastatic renal cell carcinoma may be prognostic of outcome

Circulating tumor cells in the blood and bone marrow have been examined in a variety of malignancies, including colorectal, breast, and head & neck cancers, to determine their prognostic significance.

8 May 2006

Inflammation markers identify fatigue in breast cancer survivors

Researchers at the University of California, Los Angeles have defined conditions associated with disabling fatigue that persists for years in almost a third of breast cancer survivors, according to a study in the May 1 issue of Clinical Cancer Research.

3 May 2006

Study looks at the cellular basis for immune activation in fatigued breast cancer survivors

Breast cancer survivors who suffer from persistent, debilitating fatigue years after their diagnosis have something in common: their immune systems don't shut down following treatment, according to researchers at UCLA's Jonsson Cancer Center.

3 May 2006

Lipoxin A4 regulates bronchial epithelial cell responses to acid injury

Doctors are gaining new leverage in the fight against lung injury caused by acid reflux. The paper by Bonnans et al., "Lipoxin A4 regulates bronchial epithelial cell responses to acid injury," appears in the April issue of The American Journal of Pathology and is accompanied by a commentary.

3 May 2006

Enhancing the function of the protein SOCS3 could be a more effective way to regulate cell responses

A discovery made at The Walter and Eliza Hall Institute provides new insights into enhancing the function of the protein SOCS3, which regulates the response of cells to external stimuli.

26 Apr 2006

Caspase-12 antagonists could potentially be useful in the treatment of sepsis and other inflammatory and immune disorders

According to the new study, the presence of caspase-12, which appears to modulate inflammation and innate immunity in humans, increases the body's "vulnerability to bacterial infection and septic shock" while a deficiency confers strong resistance to sepsis. This new discovery suggests that caspase-12 antagonists could be a potentially useful in the treatment of sepsis and other inflammatory and immune disorders.

26 Apr 2006

Cytokine News and Research

Drug trial fiasco induced immune system overload in patients

Reduced levels of antiinflammatory cytokines in patients with chronic widespread pain

NICE backs use of Enbrel and Raptiva to treat severe psoriasis

Scientists identify overactive protein that plays a key role in cystic fibrosis

Scientists find a cytokine against auto-immune hepatitis

Nventa granted European patent covering heat shock protein fusion to treat influenza

Sunitinib shows promise in treating metastatic renal cell cancer

Sunitinib malate drug shows significant benefits over standard treatment for advanced kidney cancer

c-myc gene found to play role in immune system

Interferon-gamma plays a critical role in damaging the cells that produce myelin

Renewed interest in studying influenza A viruses

Circulating tumor cells in the bone marrow of patients with metastatic renal cell carcinoma may be prognostic of outcome

Inflammation markers identify fatigue in breast cancer survivors

Study looks at the cellular basis for immune activation in fatigued breast cancer survivors

Lipoxin A4 regulates bronchial epithelial cell responses to acid injury

Enhancing the function of the protein SOCS3 could be a more effective way to regulate cell responses

Caspase-12 antagonists could potentially be useful in the treatment of sepsis and other inflammatory and immune disorders

Discovery points to more effective ways of regulating cell signalling

Scientists gain greater understanding of how embryos differentiate left from right

Researchers suggest drug could block metastasis or reduce pain for bone cancer patients

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Latest News