Hyperlipidemia News and Research

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Hyperlipidemia, hyperlipoproteinemia or dyslipidemia is the presence of raised or abnormal levels of lipids and/or lipoproteins in the blood. Lipids (fatty molecules) are transported in a protein capsule, and the density of the lipids and type of protein determines the fate of the particle and its influence on metabolism.

Radiation for breast cancer not likely to increase heart attack risk

In 1973, two researchers published an article in the journal Lab Investigation saying that radiation to the breast area might damage the capillaries and restrict blood flow to the heart.

4 May 2007

Use of computer-assisted drug design in drug discovery

Metabasis Therapeutics has announced that on March 27, 2007 at the American Chemical Society 233rd National Meeting and Exposition in Chicago, Dr. M. Rami Reddy presented, "Use of Computer-Assisted Drug Design in Drug Discovery: Limitations and Advantages of Available Computational Methods."

15 Apr 2007

Link between immune system and high plasma lipid levels

Researchers at the University of Chicago have found an unsuspected link between the immune system and high plasma lipid levels (cholesterol and triglycerides in the blood) in mice.

15 Apr 2007

Addition of torcetrapib to statin therapy has no benefit for atherosclerosis progression

For some patients with high cholesterol, even the most aggressive treatment with statin drugs fails to prevent coronary artery disease.

2 Apr 2007

Pharmacy care programs for elderly improve health outcomes

A pharmacy care program for elderly patients increases medication adherence, which results in improved health outcomes, according to a study posted online by JAMA: The Journal of the American Medical Association.

13 Nov 2006

Health risks for women who are extremely obese underestimated

The health risks for women who are extremely obese may be underestimated as a new study indicates they have a higher prevalence of hypertension, diabetes, and high cholesterol than women at lower levels of obesity.

4 Jul 2006

Nutritional supplement policosanol does not lower cholesterol levels

A new study suggests that use of the nutritional supplement policosanol does not lower cholesterol levels any more than placebo, apparently contradicting the results of previous studies.

23 May 2006

Grapefruits help reduce cholesterol

A grapefruit a day - particularly the red variety - can help keep heart disease at bay, according to a new study by Israeli researchers.

16 Feb 2006

Grapefruit reduces risk from heart disease

Heart disease patients who eat one grapefruit daily can significantly reduce the levels of cholesterol in their blood in comparison to patients who do not eat the fruit, a new study has found. Chronic high blood cholesterol is a major risk factor for heart disease.

16 Feb 2006

Impotence may provide a warning sign of coronary heart disease

Erectile dysfunction may provide a warning sign of significant coronary heart disease researchers from the University of Chicago report in the January 23 issue of the Archives of Internal Medicine.

23 Jan 2006

Greater use of evidence-based medicine needed in US outpatient care

Although the quality of outpatient care in the United States has improved over the last decade, greater use of evidence-based medicine is needed, however, and quality of care is not significantly associated with the patient's racial or ethnic background, according to a study in the June 27 issue of Archives of Internal Medicine.

27 Jun 2005

Metabasis and Merck collaborate to develop new treatment for diabetes, hyperlipidemia and obesity

Metabasis Therapeutics and Merck announced today that they have formed a collaboration to research, develop and commercialize novel small molecule therapeutics with potential to treat several diseases, including type II diabetes, hyperlipidemia and obesity, by activation of an enzyme in the liver called AMP-activated Protein Kinase (AMPK).

27 Jun 2005

Orlistat, a drug that decreases fat absorption, appears helpful for improving weight management in obese adolescents

When combined with diet, exercise and behavioral therapy, orlistat, a drug that decreases fat absorption, appears helpful for improving weight management in obese adolescents, compared with placebo, according to an article in the June 15 issue of JAMA: The Journal of the American Medical Association.

14 Jun 2005

Metabolic syndrome linked to testosterone deficiency

Among men studied, those with a history of diabetes, hypertension or hyperlipidemia have a higher prevalence of hypogonadism, according to new research issued today at the American Association of Clinical Endocrinologists (AACE) Fourteenth Annual Meeting and Clinical Congress.

18 May 2005

Targeted Genetics announces new patent for Hyperlipidemia

Targeted Genetics Corporation announced today issuance of U.S. patent #6,887,463, entitled, "Methods and Compositions for Gene Therapy for the Treatment of Defects in Lipoprotein Metabolism."

11 May 2005

Risk scores may identify young individuals with atherosclerosis

Young people with atherosclerotic lesions may be identified by a risk score calculated from coronary heart disease factors like obesity, sex, age, cholesterol, and smoking, according to an article in the April 25 issue of Archives of Internal Medicine.

25 Apr 2005

Modest triglyceride elevations linked to coronary artery disease risk

Even modest increases in blood levels of triglycerides, as well as a type of high cholesterol known as type III hyperlipidemia, are strongly associated with coronary artery disease in people with a family history of the disease, according to a new study in the April 5, 2005, issue of the Journal of the American College of Cardiology.

5 Apr 2005

Alteration of steroid receptor genes creates fat burning muscle

The Salk Institute scientist who earlier discovered that enhancing the function of a single protein produced a mouse with an innate resistance to weight gain and the ability to run a mile without stopping has found new evidence that this protein and a related protein play central roles in the body's complex journey to obesity and offer a new and specific metabolic approach to the treatment of obesity related disease such as Syndrome X (insulin resistance, hyperlipidemia and atherosclerosis).

4 Apr 2005

New trial for treatment of liver disease

The Nonalcoholic Steatohepatitis (NASH) Clinical Research Network is launching its first two clinical trials for the study of NASH, a liver disease that resembles alcoholic liver disease but occurs in patients who drink little or no alcohol.

3 Apr 2005

HIV is not an independent risk factor for severe heart disease

Infection with human immunodeficiency virus (HIV) is no longer an automatic death sentence, thanks to the use of highly active anti-retroviral therapy (HAART).

8 Mar 2005