Monocyte News and Research

RSS

New insights into the cellular programs that promote resolution of inflammation during aging

Aging is associated with chronic, nonresolving inflammation, or "inflammaging," that can lead to tissue dysfunction.

6 Dec 2023

New study shows Spirulina and high-intensity training combo reduces obesity complications in men

The effects of combining high-intensity interval training (HIIT) with spirulina supplements to mitigate cardiometabolic disease risk.

27 Nov 2023

Understanding asthma: The surprising influence of gut bacteria

The role of specific gut microbes in asthma.

15 Nov 2023

Placental inflammation's role in adult depression and heart disease

An expression signature related to inflammation expressed in Hofbauer cells in the placenta, calculating polygenic risk scores to predict its expression.

14 Nov 2023

Study reveals no neuroinflammation in long COVID patients with neuropsychiatric symptoms

In a JAMA Network Open study, researchers found no evidence of neuroinflammation or blood-brain barrier dysfunction in cerebrospinal fluid markers of individuals with post-COVID-19 condition and neuropsychiatric symptoms compared to controls. The study, which assessed cytokines, chemokines, and neuroinflammation markers, suggests that persistent central nervous system immune activation may not be the primary driver of neurological long COVID symptoms.

13 Nov 2023

Next-generation ovarian cancer therapy: Engineered Vδ2 T cells show promise in preclinical trials

A prospective path for allogeneic cellular immunotherapies.

13 Nov 2023

How the gut microbiome contributes to schizophrenia

Researchers explore potential relationships between schizophrenia, the gut microbiome, the gut-brain axis, and short-chain fatty acids.

19 Oct 2023

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

The research paper explores the multifaceted role of the IL-17 family in immune response, covering everything from infection control to pathological conditions like autoimmune diseases and cancer. Future therapies may exploit IL-17's unique signaling pathways to offer more targeted and cost-effective treatments.

12 Oct 2023

Immature immune cells near dural sinuses linked to neonatal viral meningoencephalitis

Examine virus propagation within central nervous systems (CNSs) during systemic infection.

9 Oct 2023

Monocyte-derived macrophages play a crucial role in liver regeneration

The liver is a vital organ that plays a role in many essential functions, including digestion, detoxification, and metabolism.

29 Sep 2023

AI model accurately forecasts patient outcomes for common lung cancer after surgery

Researchers develop an AI model to accurately predict prognosis for patients with non-small cell lung cancer after surgery. The model, which utilized a range of preoperative and postoperative blood test results, achieved high prediction accuracy, offering a promising approach for personalized treatment plans.

25 Sep 2023

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

A recent review in the journal Immunity delves into the crucial role of dendritic cells (DCs) in shaping T-cell responses in cancer, highlighting their importance in both priming anti-tumor immunity and in ongoing immune interactions within tumors. The findings underscore the potential of DCs as key targets for next-generation cancer immunotherapies.

18 Sep 2023

Comparative genomic analysis between systemic juvenile rheumatoid arthritis and type 1 diabetes

Shared genetic markers and immune system involvement in sJRA and T1D.

15 Sep 2023

Herring roe oil's potential in psoriasis treatment

Researchers investigated the use of herring row oil to treat psoriasis, a non-communicable skin disease.

12 Sep 2023

Machine learning uncovers hidden diabetic cases among those with normal fasting glucose

Researchers identified diabetic individuals among populations with normal fasting glucose using ML.

12 Sep 2023

Senolytic therapy in mild Alzheimer’s disease shows safety in phase I trial

Researchers conducted the phase 1 trial of orally-administered senolytic therapy comprising quercetin (Q) and dasatinib (D) for symptomatic and early-stage Alzheimer's disease (AD) patients.

8 Sep 2023

Severe COVID-19 may cause long-term changes to innate immune system

Severe COVID-19 may cause long-lasting alterations to the innate immune system, the first line of defense against pathogens, according to a small study funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

18 Aug 2023