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Addressing research gaps: The UK's efforts to study lung cancer in never smokers

Study aimed to understand the specific needs of lung cancer in never smokers (LCINS) patients.

25 Jul 2023

Researchers develop novel system to identify new therapeutics for familial hypercholesterolemia

The Mona Lisa, painted by the Italian artist Leonardo da Vinci, is one of the most recognizable paintings in the world. But many people would be surprised to learn that this painting offers the first evidence of a disease called familial hypercholesterolemia (FH).

20 Jul 2023

The brain structure of superagers: identifying demographic, lifestyle, and clinical factors associated with their phenotype

Researchers used machine learning models to assess the physical and primarily mental performance of superagers.

19 Jul 2023

A machine-learning approach for monitoring the progression of Alzheimer's disease

Researchers evaluate the predictive value of a multidimensional machine learning approach for monitoring the progression of Alzheimer’s disease.

19 Jul 2023

The infection connection: investigating the impact on dementia risk, neuroimaging reveals

Researchers compared the association between neuroimaging markers of dementia and antibodies to common infection.

17 Jul 2023

Research offers hope for patients with lower lip sensory loss

The inferior alveolar nerve (IAN) is a branch of the trigeminal nerve and plays a vital role in providing sensation to the lower lip.

12 Jul 2023

Does a healthy diet protect against dementia and slow the pace of biological aging?

Study tested whether healthy diets slowed biological aging and, thus, dementia.

6 Jul 2023

SIRT1: Unlocking the secrets to better vascular health through resveratrol and energy restriction

Research investigates the effects of SIRT1 activation through resveratrol supplementation and energy restriction on vascular function in adults. The study reveals that both interventions increase circulating SIRT1, reduce sympathetic activity, and have positive impacts on vascular reactivity, indicating potential benefits for vascular health.

3 Jul 2023

Study reveals contrasting effects of sucralose on insulin and glucose control

Sucralose, a commonly used artificial sweetener, has contrasting effects on insulin secretion and glucose homeostasis. While bolus administration of sucralose enhances insulin secretion and decreases glucose levels, long-term consumption exacerbates insulin resistance and glucose intolerance, particularly in combination with a high-fat diet. The study highlights the involvement of the T1R3-ERK1/2 pathway in sucralose-induced insulin resistance in the liver.

22 Jun 2023

Could mutated blood cells hold the key to lower Alzheimer's risk?

Researchers tested whether clonal hematopoiesis of indeterminate potential (CHIP) status was associated with Alzheimer's disease.

19 Jun 2023

High lipoprotein(a) levels linked to repeated heart disease events in older adults

Researchers report that high lipoprotein(a) levels were linked to repeated coronary heart disease events in older adults.

18 Jun 2023

Research explores complex relationship between cholesterol and breast cancer risk

Research explores the complex relationship between cholesterol and breast cancer risk, with some studies suggesting an increased risk with elevated cholesterol levels while others find an inverse association.

15 Jun 2023

Gut microbiota holds clues to predicting Alzheimer's risk

Gut microbiome alterations in preclinical Alzheimer's disease (AD) were investigated, revealing distinct taxonomic composition and potential markers of AD risk. These findings contribute to understanding AD pathology and offer insights into gut-derived markers for AD.

15 Jun 2023

New data challenge seeks to unravel how lipoprotein(a) levels impact risk of cardiovascular disease

The American Heart Association, the world's leading voluntary organization focused on heart and brain health, invites scientific researchers across the globe to compete in a new data challenge to better inform the scientific understanding of how lipoprotein(a) [Lp(a)] levels impact the risk of cardiovascular disease and stroke.

12 Jun 2023

Sleep-disordered breathing in cognitively unimpaired amyloid-positive individuals may exacerbate neurodegeneration in medial temporal lobe subregions

A new study investigated the link between SDB severity and the volume of medial temporal lobe (MTL) substructures. In addition, it also evaluated the association between SDB and MTL subregions volumes with episodic memory performance.

2 Jun 2023

Boiled coffee overload: Consuming six or more cups daily linked to higher dementia and Alzheimer's risk

Researchers examine the potential relationship between tea and coffee consumption during midlife and the risk of developing dementia in later life.

30 May 2023

Case study: Experimental lecanemab treatment causes adverse outcomes in 65-year-old woman with Alzheimer's disease

In a noteworthy case study published in the Journal of Alzheimer's Disease investigators report autopsy findings in a 65-year-old woman with Alzheimer's disease (AD) who received three open label infusions of the experimental anti-amyloid beta (Aβ) antibody drug lecanemab.

25 May 2023

Alzheimer’s development: Study reveals why apoE4 gene fails to protect the brain from inflammation

A possible explanation has been found in a study for why apoE4, the most significant genetic risk factor associated with Alzheimer's disease, fails to protect the brain from inflammation.

25 May 2023

Revolutionizing Alzheimer's care: Towards a future of personalized medicine and empowered patients

research paper presents a perspective on tackling the healthcare challenge of Alzheimer's disease (AD) by shifting focus to pre-dementia stages and advocating for personalized medicine through improved diagnosis, prediction, and prevention strategies, empowering patients to actively manage their health and delay the onset of dementia.

22 May 2023

Are higher blood pressure, glucose, and low-density lipoprotein cholesterol in stroke survivors associated with cognitive decline?

The study assessed whether high blood pressure, glucose, and low-density lipoprotein cholesterol accelerated their cognitive decline.

19 May 2023