Genome Editing News and Research

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New technology can rapidly analyze the metabolic state of lipids in cells

Professor Itaru Hamachi, Lecturer Tomonori Tamura, and Assistant Professor Masaki Tsuchiya of Kyoto University have developed a new technology called O-ClickFC (Organelle-selective click labeling with flow cytometry), which can, at a very high speed, analyze the metabolic state of lipids in cells.

27 Mar 2023

Study provides evidence for a strong role of autophagy in controlling intracellular infections

Researchers at the Francis Crick Institute have found that the body's process of removing old and damaged cell parts, is also an essential part of tackling infections that take hold within our cells, like TB.

23 Mar 2023

Avanced genome editing technology could be used as a one-time treatment for CD3 delta SCID

A new UCLA-led study suggests that advanced genome editing technology could be used as a one-time treatment for the rare and deadly genetic disease CD3 delta severe combined immunodeficiency.

21 Mar 2023

CRISPR-based genome editing restores the vision of mice with retinitis pigmentosa

Researchers in China have successfully restored the vision of mice with retinitis pigmentosa, one of the major causes of blindness in humans.

17 Mar 2023

Study sheds new light on a key protein involved in the process of spermiation

In order to achieve good times in their races, many Olympic swimmers wear swimsuits that are low in water resistance.

13 Mar 2023

Scientists discover how excess oxygen changes a handful of proteins in the cells

When it comes to oxygen, you can have too much of a good thing. Breathing air that contains higher levels of oxygen than the usual 21 percent found in Earth's atmosphere can cause organ damage, seizures, and even death in people and animals, particularly if it's in excess of the body's oxygen needs.

8 Mar 2023

Common scientific method to analyze DNA in early human embryos fails to accurately reflect gene edits

A commonly used scientific method to analyze a tiny amount of DNA in early human embryos fails to accurately reflect gene edits, according to new research led by scientists at Oregon Health & Science University.

7 Mar 2023

Genome editing could help save rice crops threatened by climate change

A review of gene editing techniques suggests that the CRISPR/Cas (clustered regularly interspaced short palindromic repeats/Cas) method could be a possible 'savior' for rice crops threatened by climate change and high food demand.

3 Mar 2023

Genome editing techniques based on bacterial-artificial-chromosome in herpesvirus research

In a recent study published in the Microorganisms journal, researchers in China reviewed the uses of bacterial-artificial-chromosome (BAC)-based genome editing techniques in herpesvirus research.

28 Feb 2023

Genome editing prevents hypertrophic cardiomyopathy in mice

In a recent study published in the journal PLoS Digital Health, researchers pursued one-time cures for hypertrophic cardiomyopathy (HCM). They used a previously constructed murine model of HCM, designated as R403Q-129SvEv, to evaluate two different genetic therapies, as follows:

19 Feb 2023

Scientists discover a protein in the lung that blocks SARS-CoV-2 infection

University of Sydney scientists have discovered a protein in the lung that blocks SARS-CoV-2 infection and forms a natural protective barrier in the human body.

9 Feb 2023

The human body develops strategies to prevent the immune response from overshooting its mark

The signaling molecules of the immune system should trigger a response only where necessary. To prevent a life-threatening spread to the rest of the body, connective tissue can absorb these molecules like a sponge.

3 Feb 2023

Pulmonary surfactant-mediated inflammatory response against SARS-CoV-2

Researchers discuss the role of a surfactant-mediated inflammatory response employed by human lungs against SARS-CoV-2.

3 Feb 2023

Novel tool uses AI to predict the efficacy of genome-editing repair options

Researchers at the University of Zurich have developed a new tool that uses artificial intelligence to predict the efficacy of various genome-editing repair options.

2 Feb 2023

10 years of CRISPR genome editing: Advances, limitations, and future potential

In the decade since the publication of CRISPR-Cas9 as a genome editing technology, the CRISPR toolbox and its applications have profoundly changed biological research, enabling advances through applications in plants, animals, and humans.

20 Jan 2023

Targeting T cell iron metabolism may offer a new approach for treating lupus

Targeting iron metabolism in immune system cells may offer a new approach for treating systemic lupus erythematosus (SLE) -; the most common form of the chronic autoimmune disease lupus.

13 Jan 2023

Study details the “immunometabolic editing” mechanism of tumor evolution

A Ludwig Cancer Research study has discovered that the immune system's surveillance of cancer can itself induce metabolic adaptations in the cells of early-stage tumors that simultaneously promote their growth and equip them to suppress lethal immune responses.

5 Jan 2023

Salk researchers shed new light on specific mechanisms that activate oncogenes

Cancer, caused by abnormal overgrowth of cells, is the second-leading cause of death in the world. Researchers from the Salk Institute have zeroed in on specific mechanisms that activate oncogenes, which are altered genes that can cause normal cells to become cancer cells.

7 Dec 2022

Rogue killer T cells associated with leukemia drive autoimmune diseases

Gene variants associated with leukemia can produce 'rogue' immune cells that drive autoimmune diseases, according to a new study from the Garvan Institute of Medical Research.

28 Nov 2022

New CRISPR approach is a leap forward in developing personalized treatment for cancer

For the first time, scientists have used CRISPR technology to insert genes that allow immune cells to focus their attack on cancer cells, potentially leaving normal cells unharmed and increasing the effectiveness of immunotherapy.

10 Nov 2022