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Researchers design one-step procedure for improving effective of adoptive cell immunotherapy against solid tumors

Researchers developed a one-step method to engineer multifunctional M1 phenotype macrophages.

14 Aug 2023

Metrion Biosciences announces launch of Good Laboratory Practice (GLP) hERG Screening Service

Metrion Biosciences Limited, the specialist ion channel contract research and drug discovery company, today announced it has received notification from the UK’s Medicines and Healthcare Products Regulatory Agency (MHRA) that the Company is now a member of the UK GLP (Good Laboratory Practice) Compliance Monitoring Programme, and is, therefore, able to offer GLP compliant hERG ion channel screening services to the global life sciences community.

From Metrion Biosciences Limited 7 Aug 2023

Neoantigen discovery sheds light on cancer immunogenicity

Researchers reported a proteogenomic approach to investigate fresh solid melanoma tumor material.

4 Aug 2023

Multifunctional Ga-based nanoparticles combine cancer phototherapy with immunotherapy

Researchers develop a novel cancer theranostic agent that can covert light energy to heat and in turn destroy cancer cells

4 Aug 2023

Study reveals mechanism through which insulin-like growth factors facilitate brain plasticity

Research from the Max Planck Florida Institute for Neuroscience has identified a mechanism through which insulin-like growth factors facilitate brain plasticity.

3 Aug 2023

Analytical and clinical evaluation of antigen-based rapid diagnostic tests against the most encountered SARS-CoV-2 variants

A recent study has assessed the sensitivity of Ag-RDTs against the most prevalent BA.5 Omicron sub-lineage.

2 Aug 2023

Cancer's silent progression: research delves into evolutionary clues in breast cancer

Researchers performed phylogenetic analyses to trace the evolution of breast cancer and precursor lesions.

2 Aug 2023

The essential role of the MPL36 protein in leptospirosis

The Leptospira membrane protein L36 (MPL36) is essential for its pathogenesis.

31 Jul 2023

New technique could improve early detection of cancer metastasis

Metastasis occurs when cancer cells acquire the ability to spread and form new tumors in different places in the body, usually by traveling within blood or lymph vessels.

24 Jul 2023

Customizing carbon nanotube biosensors to detect bacteria and viruses

The new sensor design resembles a molecular toolbox that can be used to quickly assemble sensors for a variety of purposes.

21 Jul 2023

New brain-penetrant agonist shows promise in protecting dopamine neurons for Parkinson's disease treatment

Researchers reported on Nurr1 as a promising therapeutic target for managing Parkinson's disease (PD).

20 Jul 2023

Study provides new insights into the mechanism of Dmc1 filament assembly

Homologous recombination (HR) is an important process that plays multiple crucial roles during meiosis, a type of cell cycle dedicated to sexual reproduction.

19 Jul 2023

The infection connection: investigating the impact on dementia risk, neuroimaging reveals

Researchers compared the association between neuroimaging markers of dementia and antibodies to common infection.

17 Jul 2023

Unveiling the key defender: PLSCR1 identified as a potent anti-SARS-CoV-2 factor in COVID-19 immunity

Researchers identified the anti-SARS-CoV-2 function of phospholipid scramblase 1 (PLSCR1).

14 Jul 2023

Plant cell study reveals new role for enzyme in lipid metabolism

A new study by Rice University bioscientists explains how basic cellular structures common to most life forms collaborate to fuel growth in a model plant organism. The findings could shed light on corresponding mechanisms in human cells.

12 Jul 2023

Orexin is crucial to the regulation of pupil size, research shows

The way the brain regulates pupil size is different from previously thought: fundamentally responsible is the neurotransmitter orexin, as researchers at ETH Zurich have now shown.

11 Jul 2023

Phosphorothioate backbone modification enhances aptamer-drug conjugate for pancreatic cancer therapy

Pancreatic cancer is a complex and deadly solid tumor that poses significant challenges for both diagnosis and treatment.

10 Jul 2023

New study shows circulating anti-insulin CD4 T cells reflect progression of anti-islet immunity

In a recent study published in Science Translational Medicine, researchers profile antigen-specific helper clusters of differentiation 4-positive (CD4+) T-lymphocytes to determine anti-islet autoimmunity among mice and humans.

9 Jul 2023

Metrion Biosciences expands senior leadership team with appointments of Dr Robert Kirby as COO and Dr Edward Stevens as CSO

Metrion Biosciences Limited (“Metrion”), is a specialist ion channel contract research and drug discovery company.

From Metrion Biosciences Limited 6 Jul 2023

Arima Genomics continues momentum toward clinic with formation of clinical advisory board

Arima Genomics, Inc., a company leveraging 3D genomics to reveal actionable insights to improve human health and drive discovery in the life sciences, today announced the formation of a clinical advisory board to help the company advance its 3D genomics technologies into the clinical oncology and biopharmaceutical markets.

From Arima Genomics, Inc. 5 Jul 2023