Proliferation News and Research

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LTBR identified as potential target for cancer immunotherapy and marker of poor prognosis

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, "Systematic analysis of the prognostic value and immunological function of LTBR in human cancer."

23 Jan 2024

Immune checkpoint inhibitor target found to promote skin cancer growth

Programmed cell death 1 (PD-1) is an important target for immune checkpoint inhibitor therapies that block its signaling and boost T-cell activity. PD-1 inhibitors have been approved for treating various types of cancer.

19 Jan 2024

Ludwig scientists deconstruct the blood supply of brain metastases

A Ludwig Cancer Research study has generated a granular portrait of how the cellular and molecular components of the blood vessels that feed brain metastases of melanoma and lung and breast cancers differ from those of healthy brain tissue, illuminating how they help shape the internal environment of tumors to support cancer growth and immune evasion.

19 Jan 2024

Antiviral hope emerges as viruses linked to multiple myeloma

A few years ago, a patient was cured of multiple myeloma after being treated for hepatitis C, astounding researchers from the group led by Joaquín Martínez, from the H12O-CNIO Haematological Tumours Clinical Research Unit, a collaboration between the Hospital 12 de Octubre (H12O) and the National Cancer Research Centre (CNIO).

19 Jan 2024

Annexin-A1 targeted therapy beats several cancers

A new study published in Nature's cancer journal Oncogene highlights the effectiveness of MDX-124, the first therapeutic drug to target annexin-A1, a protein which is overexpressed in several cancer types and promotes tumour progression.

19 Jan 2024

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

Researchers compared SARS-CoV-2 Omicron variant of concern replication in human cell lines and primary airway cultures and measured host responses to infection.

19 Jan 2024

RBMX protein emerges as key player in cancer progression and immunotherapy response

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, "Aberrant RBMX expression is relevant for cancer prognosis and immunotherapy response."

17 Jan 2024

Jena researchers unravel PAPAS RNA's impact on breast cancer growth and metastasis

Breast cancer is the most common cancer in women. The development of breast cancer often originates from epithelial cells in the mammary gland – the very cells that specialise in milk production during and after pregnancy.

16 Jan 2024

Revolutionary brain scan lights up glioma's Achilles heel

Recently, a team of South Korean researchers led by nuclear medicine physician and Professor Yun Mijin from Severance Hospital in collaboration with Director C. Justin LEE of the Center for Cognition and Sociality within the Institute for Basic Science (IBS) made a new discovery that can revolutionize both the diagnosis and treatment of glioblastoma.

16 Jan 2024

Is AI the future of personalized hypertension risk assessment, diagnosis, and treatment?

Artificial intelligence (AI) applications for treating hypertension (HTN) and its comorbidities.

16 Jan 2024

Hundreds of chemicals linked to breast cancer risk identified in new study

Study identifies 921 chemicals potentially linked to breast cancer risk, using a framework evaluating genotoxicity and endocrine activity.

14 Jan 2024

RBM5 identified as key regulator of HOXA9 in acute myeloid leukemia

The protein HOXA9 is overexpressed in most acute myeloid leukemia (AML) cases and is associated with poor patient outcomes.

12 Jan 2024

Uncovering the role of ER-mitochondria connections in muscle atrophy

The loss of muscle mass, or muscle atrophy, is a relatively common condition in today's aging and increasingly sedentary societies.

12 Jan 2024

Key protein EPAC1 found to regulate brown fat growth, offering obesity treatment potential

Study reveals that EPAC1 protein plays a crucial role in regulating the growth of brown and beige adipose tissue, offering potential avenues for treating obesity and improving cardiometabolic health.

11 Jan 2024

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

In our latest interview, News-Medical speaks with Rosanna Zhang from ACROBiosystems about utilizing organoids for disease modeling in the field of neuroscience research.

From Aneuro - An ACROBiosystems Brand 11 Jan 2024

Pangolins' genetic makeup linked to increased coronavirus susceptibility

Research reveals pangolins' vulnerability to coronavirus due to innate immune gene pseudogenization, impacting their antiviral response.

10 Jan 2024

Unearthing individual-level mutation risk patterns

Mutations, which occur continuously in every cell of our bodies, are a key contributor to cancer, ageing, and neurodegeneration.

10 Jan 2024

New peptide library paves the way for targeting elusive cancer factor MYC

Researchers developed a second-generation NTB bicyclic peptide library, identifying NT-B2R, a peptide that effectively targets MYC, a key factor in most human cancers, demonstrating its potential in inhibiting MYC transcription activities and cancer cell proliferation.

8 Jan 2024

Comprehensive insights on pathophysiology and clinical management of atrial fibrillation

Atrial fibrillation (AF) is a major global health concern impacting millions and causing symptoms like palpitations, dyspnea, fatigue, dizziness, and chest discomfort.

8 Jan 2024

Breakthrough drug halts lung cancer and brain metastases

D'Or Institute for Research and Education (IDOR) played an important role in the phase III LIBRETTO-431 multicenter study, which evaluated the efficacy and safety of selpercatinib compared to control treatment, which consisted of platinum-based chemotherapy associated or not with pembrolizumab (immune checkpoint inhibitor) in non-small cell lung cancer (NSCLC).

5 Jan 2024

Proliferation News and Research

LTBR identified as potential target for cancer immunotherapy and marker of poor prognosis

Immune checkpoint inhibitor target found to promote skin cancer growth

Ludwig scientists deconstruct the blood supply of brain metastases

Antiviral hope emerges as viruses linked to multiple myeloma

Annexin-A1 targeted therapy beats several cancers

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

RBMX protein emerges as key player in cancer progression and immunotherapy response

Jena researchers unravel PAPAS RNA's impact on breast cancer growth and metastasis

Revolutionary brain scan lights up glioma's Achilles heel

Is AI the future of personalized hypertension risk assessment, diagnosis, and treatment?

Hundreds of chemicals linked to breast cancer risk identified in new study

RBM5 identified as key regulator of HOXA9 in acute myeloid leukemia

Uncovering the role of ER-mitochondria connections in muscle atrophy

Key protein EPAC1 found to regulate brown fat growth, offering obesity treatment potential

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

Pangolins' genetic makeup linked to increased coronavirus susceptibility

Unearthing individual-level mutation risk patterns

New peptide library paves the way for targeting elusive cancer factor MYC

Comprehensive insights on pathophysiology and clinical management of atrial fibrillation

Breakthrough drug halts lung cancer and brain metastases

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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