Antisense News and Research

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Antisense is the non-coding strand in double-stranded DNA. The antisense strand serves as the template for mRNA synthesis.
Novel gene therapy holds potential in treating patients with epilepsy

Novel gene therapy holds potential in treating patients with epilepsy

New triple-targeting pharmacological tool developed for cancer treatment

New triple-targeting pharmacological tool developed for cancer treatment

Nanodrug targeting miR-10b shows promise in treating metastatic breast cancer

Nanodrug targeting miR-10b shows promise in treating metastatic breast cancer

Understanding the epigenetic regulation of hepatic stellate cells in NAFLD

Understanding the epigenetic regulation of hepatic stellate cells in NAFLD

Novel antisense therapy targets α-synuclein pathologies in neurodegenerative diseases

Novel antisense therapy targets α-synuclein pathologies in neurodegenerative diseases

60 years in the making: Nanoparticles revolutionize nucleotide delivery

60 years in the making: Nanoparticles revolutionize nucleotide delivery

RNA splicing modulation as a precision approach for neuroendocrine cancer treatment

RNA splicing modulation as a precision approach for neuroendocrine cancer treatment

Antisense RNA acts as a cellular 'booster' for gene expression, study finds

Antisense RNA acts as a cellular 'booster' for gene expression, study finds

Secarna Pharmaceuticals and Orbit Discovery enter collaboration to discover and develop peptide-conjugated targeted antisense oligonucleotide therapeutics

Secarna Pharmaceuticals and Orbit Discovery enter collaboration to discover and develop peptide-conjugated targeted antisense oligonucleotide therapeutics

New chemical modification improves effectiveness and safety of  ASO therapy for CNS diseases

New chemical modification improves effectiveness and safety of ASO therapy for CNS diseases

Study sheds light on the crucial role of glutamate tRNA fragments in brain aging and Alzheimer's disease

Study sheds light on the crucial role of glutamate tRNA fragments in brain aging and Alzheimer's disease

Clinical trial shows CRISPR gene editing has exciting potential to treat a rare form of blindness

Clinical trial shows CRISPR gene editing has exciting potential to treat a rare form of blindness

UK study confirms healthy habits can extend lifespan, even with genetic predispositions

UK study confirms healthy habits can extend lifespan, even with genetic predispositions

Scientists identify signaling pathway in liver cells linked to fibrosis

Scientists identify signaling pathway in liver cells linked to fibrosis

Study reveals novel approach to promote efficient uptake of ASOs into cancer cells

Study reveals novel approach to promote efficient uptake of ASOs into cancer cells

Smartphone app shows promise in detecting early signs of frontotemporal dementia

Smartphone app shows promise in detecting early signs of frontotemporal dementia

Targeting a non-encoding stretch of RNA may shrink pediatric brain tumors in mice

Targeting a non-encoding stretch of RNA may shrink pediatric brain tumors in mice

UCSF scientists discover less invasive prenatal treatment for Angelman syndrome

UCSF scientists discover less invasive prenatal treatment for Angelman syndrome

Yale School of Medicine secures $575,000 grant for Long COVID research

Yale School of Medicine secures $575,000 grant for Long COVID research

Combo of targeted and immunotherapy may boost NSCLC treatment by overcoming immune resistance and enhancing anti-tumor activity

Combo of targeted and immunotherapy may boost NSCLC treatment by overcoming immune resistance and enhancing anti-tumor activity

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