Actin News and Research

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Actin influences cancer metastases in many ways

Metastases occur when cancer cells leave a primary tumor and spread throughout the body. For this, they have to break connections with neighboring cells and migrate to other tissues.

31 Jan 2023

Repression of endothelial TLR3 is a potential mechanism of SARS-CoV-2 infection-associated lung vascular remodeling

Researchers investigated whether endothelial TLR3 insufficiency contributes to lung vascular remodeling induced by SARS-CoV-2.

30 Jan 2023

The diverse mechanisms by which galectins can regulate adaptive and innate immune responses

Researchers explored ways galectins can impact immunity and discussed the opportunities and challenges in the field.

18 Jan 2023

New Pyk2-derived peptide inhibits breast cancer metastasis

An estimated ninety percent of deaths from breast cancer are due to complications resulting from metastasis, a process in which cancer cells break away from where they first formed, travel through the blood or lymph circulatory system, and form new, metastatic tumors in other parts of the body.

17 Jan 2023

Smart molecular glue ensures the nucleus is correctly positioned for cell division

Researchers from Paul Scherrer Institute PSI and ETH Zurich have discovered how proteins in the cell can form tiny liquid droplets that act as a smart molecular glue.

19 Dec 2022

The effects of mechanical forces on musculoskeletal cells and tissues

In this interview, Dr. Marina Danalache, Lab leader at the Laboratory of Cell Biology, Department of Orthopedic Surgery, University of Tübingen talks to News-Medical Life Sciences about the ongoing research on the effects of mechanical forces on musculoskeletal cells and tissues, as well as how these forces mediate homeostasis and drive pathophysiological processes.

From Bruker BioAFM 30 Nov 2022

Cryo-electron tomography helps visualize platelet deformation due to SARS-CoV-2 spike protein

Researchers used cellular cryo-electron tomography (cryo-ET) to demonstrate the role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein in coronavirus disease 2019 (COVID-19)-triggered severe coagulopathies.

28 Nov 2022

Scientists determine 5,072 essential human genes

In a recent study published in the journal Cell, researchers examined the phenotypic landscape of multiple elusive essential human genes to create a detailed genotype-phenotype resource outlining the phenotypic consequences of disrupting fundamental cellular processes.

8 Nov 2022

Health of mothers, fetuses, and children are all affected by the maternal environment

A recent editorial published in the journal BMC Medicine examined existing literature for associations between the mother's and offspring's health outcomes and a broad range of maternal characteristics related to pregnancy and postnatal phenotypes and complications.

3 Nov 2022

Higher viscosity of extracellular fluid enhances cancer dissemination

New research findings show how higher viscosity, or resistance to flow, of the extracellular fluid that surrounds cells enables cancer cells to migrate more rapidly from a primary tumor to other sites in the body.

2 Nov 2022

How does the ISG15/ISGylation system modulate Vaccinia virus infection?

Researchers demonstrated how interferon-stimulated gene 15 (ISG15) is involved in the Vaccinia virus (VACV) dissemination.

1 Nov 2022

Researchers fabricate a non-porous biodegradable vascular graft

Researchers developed a novel small-diameter biodegradable vascular graft that aids the formation of elastin-containing structures in the intima-media, which is important for the normal functioning of the artery.

26 Oct 2022

Monkeypox virus infection and its persistence in the testes of infected crab-eating macaques

Researchers performed retrospective detection of the monkeypox virus in the testes of nonhuman primates.

22 Oct 2022

“Mystery gene” matures a main component of the cell skeleton

"I'm a professional pin-in-a-haystack seeker," geneticist Thijn Brummelkamp responds when asked why he excels at tracking down proteins and genes that other people did not find, despite the fact that some have managed to remain elusive for as long as forty years.

29 Sep 2022

Actin News and Research

Actin influences cancer metastases in many ways

Repression of endothelial TLR3 is a potential mechanism of SARS-CoV-2 infection-associated lung vascular remodeling

The diverse mechanisms by which galectins can regulate adaptive and innate immune responses

New Pyk2-derived peptide inhibits breast cancer metastasis

Smart molecular glue ensures the nucleus is correctly positioned for cell division

The effects of mechanical forces on musculoskeletal cells and tissues

Cryo-electron tomography helps visualize platelet deformation due to SARS-CoV-2 spike protein

Scientists determine 5,072 essential human genes

Health of mothers, fetuses, and children are all affected by the maternal environment

Higher viscosity of extracellular fluid enhances cancer dissemination

How does the ISG15/ISGylation system modulate Vaccinia virus infection?

Researchers fabricate a non-porous biodegradable vascular graft

Monkeypox virus infection and its persistence in the testes of infected crab-eating macaques

“Mystery gene” matures a main component of the cell skeleton

Scientists uncover key details of an immune-cell process that underlies excessive inflammation

Tumors generate unique, temporary cell-in-cell structures to evade immunotherapy

RIT scientist receives $1.7 million NIH award to study how cells control the size of organelles

Researchers use sea anemone to understand how behavior impacts body shape during early development

Disruption of actin cytoskeleton is key to triggering human immune response, research finds

Study reveals a vital route through which fascin promotes cancer development

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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