Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Study reveals accelerated progression of Alzheimer's in people with Down syndrome

Nearly all adults with Down syndrome will develop evidence of Alzheimer's disease by late middle age.

16 Apr 2024

Junk food-filled diet in teens may disrupt brains' memory ability for a long time

A new USC-led study on rats that feasted on a high-fat, sugary diet raises the possibility that a junk food-filled diet in teens may disrupt their brains' memory ability for a long time.

16 Apr 2024

Common HIV drugs linked to reduced Alzheimer's disease risk

Alzheimer's disease (AD) currently afflicts nearly seven million people in the U.S. With this number expected to grow to nearly 13 million by 2050, the lack of meaningful therapies represents a major unmet medical need.

16 Apr 2024

Study unlocks genetic secrets in APOEε4 carriers that could defend against Alzheimer's

Researchers utilized whole-genome sequencing and pathway analysis to uncover protective genetic variations against Alzheimer's disease in APOEε4 carriers, revealing a crucial role for extracellular matrix-related genes in mitigating the disease's progression.

15 Apr 2024

Mayo Clinic study offers insights into lucid episodes in dementia

A recent Mayo Clinic study published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association investigated lucid episodes in people living with later stages of dementia, providing insights into how these occurrences reveal themselves.

13 Apr 2024

Geraniol alleviates cognitive decline in D-galactose-induced aging mice

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 6, entitled, "Geraniol attenuates oxidative stress and neuroinflammation-mediated cognitive impairment in D galactose-induced mouse aging model."

12 Apr 2024

Newly discovered genetic variant reduces the odds of developing Alzheimer's disease

Columbia researchers have discovered a genetic variant that reduces the odds of developing Alzheimer's disease by up to 70% and may be protecting thousands of people in the United States from the disease.

10 Apr 2024

Researchers identify the most harmful modifiable risk factors for dementia

Researchers from the Nuffield Department of Clinical Neurosciences at the University of Oxford have used data from UK Biobank participants to reveal that diabetes, traffic-related air pollution and alcohol intake are the most harmful out of 15 modifiable risk factors for dementia.

10 Apr 2024

Network analysis reveals subtle changes associated with subjective cognitive decline

We all lose our car keys or our glasses from time to time. Most people would be correct to laugh it off as a normal part of aging.

9 Apr 2024

Gut-friendly psychobiotics could brighten moods and fight depression

Review uncovers that psychobiotics may offer supportive treatment for depression by restoring gut microbiome balance and positively influencing the microbiome-gut-brain axis, which is crucial for mental health and well-being.

8 Apr 2024

Human neuron model identifies potential therapeutic targets for Alzheimer's disease

Weill Cornell Medicine scientists have developed an innovative human neuron model that robustly simulates the spread of tau protein aggregates in the brain-;a process that drives cognitive decline in Alzheimer's disease and frontotemporal dementia.

5 Apr 2024

Hypertension linked to higher dementia risk in middle-aged patients

Study investigates the relationship between hypertension in middle-aged individuals and the increased risk of developing dementia, utilizing the CAIDE score for dementia risk prediction in a cohort of white Argentinian hypertensive patients.

4 Apr 2024

Unlocking the secrets of long-lived RNAs in brain cells

After two decades in the United States, Martin Hetzer returned home to Austria in 2023 to become the 2nd President of the Institute of Science and Technology Austria (ISTA).

4 Apr 2024

UCL and Oxford lead major dementia diagnosis trials

Thousands of people in the UK are to take part in countrywide trials to identify accurate and quick blood tests that can diagnose dementia, led by research teams at UCL and Dementias Platform UK, based at the University of Oxford.

4 Apr 2024

Study evaluates the feasibility of discontinuing CLL specialist care

A study published today in Blood Advances showed that among patients in Denmark who had slow-growing chronic lymphocytic leukemia (CLL) with no symptoms and a low risk for ever needing treatment, those who stopped seeing their doctors for specialized follow-up had fewer hospital visits, fewer infections, and similar survival after three years compared to those who continued to undergo specialized follow-up.

4 Apr 2024

New treatments in sight for challenging neuropsychiatric symptoms in neurodegenerative diseases

Study reviews the advancements in pharmacological treatments for neuropsychiatric syndromes in neurodegenerative disorders, discussing the complexities of managing symptoms such as depression, disinhibition, apathy, psychosis, and agitation to improve patient care.

3 Apr 2024

Earlier menopause combined with high cardiovascular risk linked to cognitive problems later

Earlier menopause combined with higher risk of cardiovascular disease is linked to an increased risk of thinking and memory problems later, according to a new study published in the April 3, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

3 Apr 2024

Alzheimer's Disease News and Research

Further Reading

Study reveals accelerated progression of Alzheimer's in people with Down syndrome

Junk food-filled diet in teens may disrupt brains' memory ability for a long time

Common HIV drugs linked to reduced Alzheimer's disease risk

Study unlocks genetic secrets in APOEε4 carriers that could defend against Alzheimer's

Mayo Clinic study offers insights into lucid episodes in dementia

Geraniol alleviates cognitive decline in D-galactose-induced aging mice

Newly discovered genetic variant reduces the odds of developing Alzheimer's disease

Researchers identify the most harmful modifiable risk factors for dementia

Network analysis reveals subtle changes associated with subjective cognitive decline

Gut-friendly psychobiotics could brighten moods and fight depression

Human neuron model identifies potential therapeutic targets for Alzheimer's disease

Hypertension linked to higher dementia risk in middle-aged patients

Unlocking the secrets of long-lived RNAs in brain cells

UCL and Oxford lead major dementia diagnosis trials

Study evaluates the feasibility of discontinuing CLL specialist care

New treatments in sight for challenging neuropsychiatric symptoms in neurodegenerative diseases

Earlier menopause combined with high cardiovascular risk linked to cognitive problems later

Innovative approach to disrupt misfolding of tau proteins in neurodegenerative diseases

Researchers find a promising approach to remove amyloid plaques in Alzheimer's disease

Atomic-level structural models of enzymes provide disease insights

Aneuro: A Year of Neuroscience in Review eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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