Aniridia News and Research

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Cornea implant made of collagen from pig’s skin restores vision

In this interview, News-Medical speaks to Professors Neil Lagali and Mehrdad Rafat about their latest research, which detailed a bioengineered corneal tissue for minimally invasive vision restoration in advanced keratoconus in two clinical cohorts.

23 Aug 2022

Scientists publish the most extensive description to date of WAGR syndrome

Researchers from Children's Hospital of Philadelphia (CHOP) have published the most comprehensive description to date of the rare genetic disorder known as WAGR syndrome. This new report identified several clinical issues not classically associated with the disease and provides guidance for proper diagnosis, management, and potential treatment options.

21 Dec 2021

Study: Specific class of drugs can be repurposed to treat genetic diseases

Researchers at the University of Illinois Chicago have published a study showing a promising approach to using drug repurposing to treat genetic diseases.

17 Dec 2020

Scientists test repurposed drugs for treatment of rare eye condition

Fight for Sight is funding scientists from the University of Aberdeen to test two repurposed drugs for the treatment of the rare eye condition aniridia, which causes blindness.

6 Dec 2019

People with sight problems could benefit from new surgical trial

People with sight problems could benefit from a surgical trial advance that has been shown to help restore the surface of the eye.

29 Jan 2019

FDA approves first stand-alone prosthetic iris in the U.S.

The U.S. Food and Drug Administration today approved the first stand-alone prosthetic iris in the United States, a surgically implanted device to treat adults and children whose iris (the colored part of the eye around the pupil) is completely missing or damaged due to a congenital condition called aniridia or other damage to the eye.

30 May 2018

New method to identify, sort stem cells may help restore vision to people with damaged corneas

Researchers working as part of the University of Georgia's Regenerative Bioscience Center have developed a new way to identify and sort stem cells that may one day allow clinicians to restore vision to people with damaged corneas using the patient's own eye tissue.

3 Mar 2017

Small molecule nonsense suppression strategy for aniridia-associated defects

Congenital aniridia is a progressive disease that is associated with improper development of eye structures as well as abnormalities in the brain and pancreas. A variety of nonsense mutations in the PAX6 gene are linked with aniridia; however, despite understanding the genetic basis of the disease, few treatment and prevention strategies are available.

22 Dec 2013

Scientists develop new potential cure for rare eye disease

University of British Columbia and Vancouver Coastal Health scientists have developed a potential cure for a rare eye disease, showing for the first time that a drug can repair a birth defect.

22 Dec 2013

Rigid gas-permeable lenses correct vision after ocular trauma

Fitting a rigid gas-permeable contact lens into the eyes of patients treated surgically for ocular trauma can improve their visual acuity and are well tolerated, report researchers from China.

7 Sep 2012

UBC researchers lead development of new 'toolbox of MiniPromoters' for gene research and therapy

University of British Columbia researchers have led the development of a new "toolbox of MiniPromoters" for research and future therapies on brain, spinal cord and eye function.

31 Aug 2010

Simple stem cell technique restores sight to damaged eyes

In a world-first breakthrough by Australian scientists, the eyesight in a damaged eye has been restored by using stem cells from the eye itself

27 May 2009

Stem cell breakthrough restores sight to sufferers of corneal disease

In a world-first breakthrough, University of New South Wales (UNSW) medical researchers have used stem cells cultured on a simple contact lens to restore sight to sufferers of blinding corneal disease.

27 May 2009

Low levels of 'brain derived neurotrophic factor' may lead to obesity

A brain chemical that plays a role in long term memory also appears to be involved in regulating how much people eat and their likelihood of becoming obese, according to a National Institutes of Health study of a rare genetic condition.

28 Aug 2008

Twin research reveals gene that may play a crucial part in the development of myopia

New research carried out by doctors in the Twin Research Unit at St Thomas’ Hospital, London, indicates that a gene called PAX6 may play a crucial part in the development of myopia.

31 Jul 2004