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Recaticimab injection every 1-3 months may safely lower bad cholesterol

A new PCSK9 inhibitor (recaticimab) injected every one to three months may work safely and provide more flexible dosing to lower cholesterol, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Single injection of new medication effectively eliminates Lp(a) for nearly one year

In the first human trial of a new therapeutic, a single injection of lepodisiran reduced levels of lipoprotein(a), or Lp(a), to undetectable levels for nearly one year, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Is there an association between atrial fibrillation onset age and incident dementia?

Whether younger age at atrial fibrillation (AF) diagnosis is associated with a higher risk of incident dementia.

13 Nov 2023

Australian study shows combined genomic screening for major hereditary diseases is cost-effective and health-saving

In an Australian study published in EClinicalMedicine, researchers evaluated the impact of a combined genomic screening program for hereditary breast and ovarian cancer, Lynch syndrome, and familial hypercholesterolemia in young adults. The program proved to be cost-effective, reducing healthcare costs and averting numerous health events, while emphasizing the need for further optimization and equitable access within public healthcare systems.

12 Nov 2023

Cannabis use alters DNA methylation, with implications beyond smoking effects

A large-scale meta-analysis in Molecular Psychiatry reveals that lifetime cannabis use is associated with DNA methylation changes in peripheral blood, which could have implications for understanding the long-term health effects of cannabis consumption.

8 Nov 2023

Pharmacogenomics holds promise for personalized dementia therapies

Pharmacogenomics-based studies in the research for personalized therapeutics for dementia

8 Nov 2023

Gut health linked to Alzheimer's disease progression, experts urge dietary shift

The interactions between the gut microbiome, lipids, and Alzheimer’s disease (AD).

7 Nov 2023

Does the percentage of slow-wave sleep decline with aging, and are intra-individual declines associated with dementia risk?

Researchers investigated whether slow-wave sleep (SWS) proportions reduced as individuals aged and whether intra-individual decreases were linked to dementia risk.

1 Nov 2023

Stopping metformin early linked to higher dementia risk in older adults with type 2 diabetes

Early termination of metformin treatment in older adults with type 2 diabetes is associated with a higher risk of dementia, according to a cohort study. The research has significant implications for diabetes management, especially among those at higher risk for dementia.

29 Oct 2023

Boosting brain health with iron and manganese: A dietary defense against cognitive decline

The recent study published in Nutrients explores the link between dietary mineral intake and cognitive impairment in elderly Spanish individuals, finding that increased consumption of iron and manganese significantly reduced cognitive impairment risk in women but showed no effect in men.

25 Oct 2023

Is COVID-19 a risk factor for Alzheimer's disease?

The study explores the interconnected risks between COVID-19 and Alzheimer's Disease (AD), highlighting how SARS-CoV-2 can aggravate AD pathology through neuroinflammation and neurodegeneration. It raises significant concerns about the long-term cognitive implications of COVID-19, especially among those already at risk for AD.

23 Oct 2023

Saliva test breakthrough: Early detection for ectopic pregnancies on the horizon

Salivary proteins may offer early detection for ectopic pregnancies, potentially saving maternal lives through a non-invasive diagnostic approach. The study identifies specific proteins that are prominently present in ruptured ectopic pregnancy cases, highlighting the potential for developing a saliva-based diagnostic kit.

9 Oct 2023

Study discovers protective genetic mutation for kidney disease

African Americans have long been known to be at increased risk of kidney disease due to a dangerous genetic mutation that creates a hole in the kidney cells, but Vanderbilt University Medical Center (VUMC) researchers have now discovered a protective genetic mutation that covers the hole to eliminate the risk.

6 Oct 2023

Breakthrough antibody therapy targets Alzheimer's risk gene, offers hope for effective treatment

Researchers introduced and characterized a novel platform based on monoclonal antibodies (mAbs).

6 Oct 2023

Microglial states and their impact on Alzheimer's disease

Researchers examined 152,459 microglial transcriptomes from 443 individuals, identifying 12 transcriptional states and their relationship to Alzheimer's disease.

3 Oct 2023

Identification of Alzheimer's disease-associated micro-RNA biomarkers through network-based analysis

Micro-ribonucleic acids (miRNAs) linked to cognition and Alzheimer's disease (AD).

3 Oct 2023

Novel vaccine lowers LDL cholesterol independent of statins

The effectiveness of virus-like particle (VLP)-based vaccines targeting epitopes in the low-density lipoprotein (LDL) receptor.

2 Oct 2023

Vascular risk factors influence cognitive health differently in men and women with Alzheimer's disease

Researchers utilize imaging findings to elucidate how Alzheimer's dementia can present considerable variations depending on the sex of the individual.

27 Sep 2023

How does the APOE4 gene play both hero and villain in your health risks?

The study reveals that APOE4, a genetic risk factor for Alzheimer's Disease and cardiovascular diseases, has complex effects on mortality risk. While APOE4 carriers with higher AD neuropathology have increased mortality risk, those with low neuropathology had a reduced risk of certain cancers, warranting further research into this genetic factor's diverse impact on health outcomes.

14 Sep 2023

Could your daily routine lead to dementia? New research points to sedentary lifestyle as potential risk factor

In a recent study, researchers investigated whether accelerometer-assessed sedentary behavior was associated with incident dementia.

13 Sep 2023

Apolipoprotein News and Research

Recaticimab injection every 1-3 months may safely lower bad cholesterol

Single injection of new medication effectively eliminates Lp(a) for nearly one year

Is there an association between atrial fibrillation onset age and incident dementia?

Australian study shows combined genomic screening for major hereditary diseases is cost-effective and health-saving

Cannabis use alters DNA methylation, with implications beyond smoking effects

Pharmacogenomics holds promise for personalized dementia therapies

Gut health linked to Alzheimer's disease progression, experts urge dietary shift

Does the percentage of slow-wave sleep decline with aging, and are intra-individual declines associated with dementia risk?

Stopping metformin early linked to higher dementia risk in older adults with type 2 diabetes

Boosting brain health with iron and manganese: A dietary defense against cognitive decline

Is COVID-19 a risk factor for Alzheimer's disease?

Saliva test breakthrough: Early detection for ectopic pregnancies on the horizon

Study discovers protective genetic mutation for kidney disease

Breakthrough antibody therapy targets Alzheimer's risk gene, offers hope for effective treatment

Microglial states and their impact on Alzheimer's disease

Identification of Alzheimer's disease-associated micro-RNA biomarkers through network-based analysis

Novel vaccine lowers LDL cholesterol independent of statins

Vascular risk factors influence cognitive health differently in men and women with Alzheimer's disease

How does the APOE4 gene play both hero and villain in your health risks?

Could your daily routine lead to dementia? New research points to sedentary lifestyle as potential risk factor

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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