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Gut bacteria play a pivotal role in obesity's impact on body fat metabolism

Review explores the complex interplay between gut microbiota dysregulation in obesity and its impacts on white and brown adipose tissue metabolism, focusing on direct and indirect effects on mitochondria, highlighting potential avenues for obesity treatment through microbiota-focused strategies.

11 Apr 2024

Tumor microbiomes offer new insights for enhancing cancer therapies

Comprehensive review reveals the significant impact of tumor-resident bacteria on metastatic cancer, showing how microbiome genomes influence tumor biology, immune system response, and treatment effectiveness. It lays the groundwork for utilizing bacteria-focused therapies to complement traditional cancer treatments.

11 Apr 2024

Rethinking the germ theory: A balanced take on microbes and disease outcomes

Review explores the complexities of infectious disease outcomes through a balanced perspective, emphasizing the interplay between pathogenic microbes and host conditions, challenging the traditional germ-disease theory by proposing a more integrated view that considers both pathogen virulence and host immunity's impact on disease manifestation.

10 Apr 2024

New generative AI tool models the infant microbiome

The gut microbiome has a profound impact on the health and development of infants. Research shows that dysbiosis-;or imbalances in the microbial community-;is associated with gastrointestinal diseases and neurodevelopmental deficits.

10 Apr 2024

Study unlocks how cortisone activates the body’s natural “brakes” on inflammation

Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions.

10 Apr 2024

Human-wildlife interface: Starling movements linked to E. coli carriage

Research unveils how spotless starlings' movements, monitored via GPS, relate to the carriage and potential spread of Escherichia coli (E. coli), emphasizing the significant role of bird movement patterns in transmitting pathogens across different environments.

10 Apr 2024

Unraveling the complex web of rectal infections and the microbiome in MSM

Study delves into the relationships between various sexually transmitted infections, including Neisseria gonorrhoeae, Chlamydia trachomatis, Torquetenovirus, and high-risk HPV, and their effects on the anorectal microbiome among men who have sex with men (MSM), unveiling complex interactions that may influence infection outcomes and treatment strategies.

10 Apr 2024

Study reveals unexpected vulnerability of lung immune cells to SARS-CoV-2

The lung-cell type that's most susceptible to infection by SARS-CoV-2, the virus that causes COVID-19, is not the one previously assumed to be most vulnerable.

10 Apr 2024

UMH research reveals key role of immune protein in liver cirrhosis

The Department of Clinical Medicine at the Miguel Hernández University of Elche (UMH) leads research on the immune system's role in advanced chronic liver disease.

10 Apr 2024

Periodontal treatment after heart rhythm ablation may reduce AFib recurrence

Treating gum disease in the 3-months after a procedure to correct an irregular heartbeat known as atrial fibrillation (AFib) may lower oral inflammation and may reduce AFib recurrence, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

10 Apr 2024

High blood levels of TMAO predicts chronic kidney disease risk in future

New findings from Cleveland Clinic and Tufts University researchers show high blood levels of TMAO (trimethylamine N-oxide) predicts future risk of developing chronic kidney disease over time.

9 Apr 2024

Researchers compile a comprehensive catalog of bacteria living in cancer metastases

Researchers at the Netherlands Cancer Institute have compiled a detailed catalog of bacteria living in cancer metastases.

9 Apr 2024

Gut-friendly psychobiotics could brighten moods and fight depression

Review uncovers that psychobiotics may offer supportive treatment for depression by restoring gut microbiome balance and positively influencing the microbiome-gut-brain axis, which is crucial for mental health and well-being.

8 Apr 2024

Pioneering vaccine strategy promises to outmaneuver antimicrobial resistance

Study introduces Reverse Vaccine Development as a strategic approach to identify correlates of protection early in vaccine development against antimicrobial-resistant pathogens, aiming to mitigate risks such as significant phase-III clinical trial failures.

7 Apr 2024

Wound warriors: How microbes influence healing and infection risks

Study explores how wound microbiota affect skin repair and infection risk by altering host immune responses, underscoring the complexity of microbial interactions in wound healing.

7 Apr 2024

Combining blood pressure drug with dietary-resistant starch may help stave off diabetic kidney disease

Combining a low dose of blood pressure medication with a higher intake of dietary-resistant starch might help stave off diabetic kidney disease, according to results from a new animal study.

7 Apr 2024

Blast exposure can cause intestinal permeability, study shows

A study by New York and Rocky Mountain U.S. Department of Veterans Affairs researchers showed blast exposure can cause intestinal permeability, a condition that can lead to gut bacteria entering the bloodstream and causing problems in other parts of the body.

5 Apr 2024