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Exploring olive oil compounds oleuropein and hydroxytyrosol as potential treatments for neuroblastoma

The therapeutic potential of oleuropein (OLE) and hydroxytyrosol (HT) from olive oil.

15 Mar 2024

Choosing the right fat for keto diets: Fish oil's significant role in cancer prevention

The anti-cancer efficacy of different oils consumed as a part of ketogenic diets (KDs).

11 Mar 2024

Study unravels FOXO1's influence on blood vessel development

The human vascular system, a complex network of blood vessels, plays an essential role in maintaining health. Understanding the molecular mechanisms underlying vascular development is important for tackling age-related disorders.

9 Mar 2024

Boston College biologist wins NIH grant to study viral insulins for cancer treatment

Boston College Assistant Professor of Biology Emrah Altindis has been awarded a five-year, $2.5-million grant from the National Institutes of Health to study viral insulins and mechanisms related to IGF-1 receptor protein inhibition and its potential applications in cancer treatment.

26 Feb 2024

Natural killer cells lead the charge in cancer treatment innovation

Review synthesizes research on NK cells' role in cancer immunity and their potential in therapeutics through bioengineering, immune checkpoint inhibitors, and cell engagers, highlighting ongoing preclinical and clinical trials.

22 Feb 2024

Novel genetic locations associated with primary open-angle glaucoma identified

An international genetic study using multiancestry biobanks has identified novel genetic locations associated with primary open-angle glaucoma (POAG), the most common type of glaucoma and the leading cause of irreversible blindness globally.

20 Feb 2024

Research demonstrates a bat species' resistance to cancer, pinpoints key genes

A study reveals Myotis pilosus bats exhibit exceptional cancer resistance through gene downregulation, offering insights into natural anticancer mechanisms.

18 Feb 2024

Study finds interleukin-24 enhances CAR-T cell therapy's effectiveness against cancer stem cells

The effect of Interleukin-24 (IL-24) on CSCs and CAR-T cell therapy.

14 Feb 2024

Study demonstrates chemo-preventive properties of alpha-santalol against prostate cancer development

Extracted from the core of sandalwood trees (santalum album tree), sandalwood oil has been used for many centuries by several cultures throughout the world for perfume, soaps, incense and candles.

13 Feb 2024

Gene therapy reverses advanced heart failure in animal study

Heart failure remains the leading cause of mortality in the U.S. During a heart attack blood stops flowing into the heart.

13 Feb 2024

New mouse model illuminates lung cancer's transformation into aggressive variant

Lung tumors called adenocarcinomas sometimes respond to initially effective treatments by transforming into a much more aggressive small cell lung cancer (SCLC) that spreads rapidly and has few options for treatment.

8 Feb 2024

Monash-led study unveils potential long-term treatment for lupus

Researchers assessed Smith (Sm)-specific regulatory T cells (Tregs) efficacy in halting lupus nephritis (LN) by engineering and testing epitope-targeted Tregs for systemic lupus erythematosus (SLE) treatment.

8 Feb 2024

Study links specific inflammatory markers to increased cancer risk

The causal relevance of circulating inflammatory markers in cancer risk.

5 Feb 2024

Immune protein Ku70 key in fighting bowel cancer

Study establishes Ku70's role in tumor suppression, showing that reduced expression or mutations in this DNA repair protein significantly increase intestinal cancer risk.

30 Jan 2024

Oncofetal ecosystems linked to recurrence and immunotherapy response in liver cancer

A team of clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS), Agency for Science, Technology and Research (A*STAR), the Harry Perkins Institute of Medical Research and global research partners, has found a causal link between the presence of oncofetal ecosystems (re-emergence of fetal programme/features driven by the tumor) in the primary liver cancer hepatocellular carcinoma (HCC) and cancer recurrence and response to immunotherapy.

29 Jan 2024

Sclerostin may protect against heart disease in patients with type 2 diabetes

A study carried out by the MP20-Biomarkers of Metabolic and Bone Diseases research group at the Biohealth Research Institute in Granada (ibs.GRANADA), led by UGR Professor Manuel Muñoz Torres, has provided significant insights into the role of sclerostin in protecting against atherosclerosis in patients with type 2 diabetes.

26 Jan 2024

LTBR identified as potential target for cancer immunotherapy and marker of poor prognosis

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, "Systematic analysis of the prognostic value and immunological function of LTBR in human cancer."

23 Jan 2024

Ludwig scientists deconstruct the blood supply of brain metastases

A Ludwig Cancer Research study has generated a granular portrait of how the cellular and molecular components of the blood vessels that feed brain metastases of melanoma and lung and breast cancers differ from those of healthy brain tissue, illuminating how they help shape the internal environment of tumors to support cancer growth and immune evasion.

19 Jan 2024

Jena researchers unravel PAPAS RNA's impact on breast cancer growth and metastasis

Breast cancer is the most common cancer in women. The development of breast cancer often originates from epithelial cells in the mammary gland – the very cells that specialise in milk production during and after pregnancy.

16 Jan 2024

Hundreds of chemicals linked to breast cancer risk identified in new study

Study identifies 921 chemicals potentially linked to breast cancer risk, using a framework evaluating genotoxicity and endocrine activity.

14 Jan 2024