Dopaminergic News and Research

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IDO2 deficiency in mice leads to behavioral abnormalities resembling autism spectrum disorder

Over the past decades, scientists have made substantial progress unveiling the underlying mechanisms behind many psychiatric disorders.

4 Jan 2024

Study deciphers how misfolded protein drives dopaminergic neuron loss in Parkinson's

A so-called pathological protein long associated with Parkinson's disease has been found in a new study to trigger cells to increase protein synthesis, an event that eventually kills the subset of brain cells that die off in this neurodegenerative condition.

20 Dec 2023

Breakthrough in Parkinson's research: Scientists identify protein synthesis pathway as culprit

19 Dec 2023

Kyoto scientists map double whammy gene clusters for anxiety disorders

Anxiety disorders (ADs) affect more than 280 million people worldwide, making them one of the most common mental health conditions. ADs have a genetic basis as seen from inheritance in families, and people with one subtype of AD tend to have another subtype, suggesting a shared genetic basis.

19 Dec 2023

Organoid model unveils secrets of the brain's dopaminergic system

A new organoid model of the dopaminergic system sheds lights on its intricate functionality and potential implications for Parkinson's disease.

5 Dec 2023

Multi-ingredient herbal supplement boosts cognitive speed and gut health in seniors

In a study on elderly patients with subjective memory decline, a 90-day herbal supplement regimen improved cognitive task speed and altered gut microbiota, despite causing memory deficits. This intervention increased urinary tyrosine levels, suggesting a dopaminergic activity role in cognitive enhancements.

26 Nov 2023

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Study reveals that senolytics can reduce aging in human brain organoids and mitigate COVID-19 neuropathology, suggesting their potential as a therapeutic strategy against brain aging and coronavirus-related neurological complications.

15 Nov 2023

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

Whether USP30 inhibition can serve as a disease-modifying therapy for Parkinson's disease (PD).

15 Nov 2023

New research explores the unique effects of ADHD medications on Drosophila brain cells

The effect of two drugs used for the treatment of attention-deficit/hyperactivity disorder.

15 Nov 2023

Game-changer for Parkinson’s therapy: Innovative neuroprosthesis enhances mobility and balance

Researchers designed a neuroprosthesis replicating the natural lumbosacral spinal activation during walking for Parkinson's disease (PD) patients.

7 Nov 2023

New gene therapy strategy shows promise for Parkinson's disease

Researchers from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS) and their collaborators have developed a gene therapy strategy to selectively manipulate Parkinson's disease-affected circuitry and attenuate the core motor symptoms of Parkinson's disease in rodent and nonhuman primate animals.

2 Nov 2023

Groundbreaking study reveals most effective adjunctive drug for Parkinson's disease

The efficacy, tolerability, and safety of various anti-Parkinson's drugs.

23 Oct 2023

Hormones and high blood pressure: Study reveals endocrine culprits and targeted treatments

Researchers delve into endocrine causes of hypertension (HTN), revealing key culprits like primary aldosteronism and Cushing's syndrome. The study also evaluates the efficacy of various treatments, offering valuable insights for tackling this widespread health issue.

15 Oct 2023

Parkinson's disease-related neuronal death more likely to occur at night

Disturbances in sleep patterns and the internal biological clock are frequently associated with Parkinson's disease.

29 Sep 2023

Study upends common belief in what triggers Parkinson's disease

A new Northwestern Medicine study challenges a common belief in what triggers Parkinson's disease.

15 Sep 2023

Targeted use of ultrasound technology can lead to significant changes in brain function

The targeted use of ultrasound technology can bring about significant changes in brain function that could pave the way towards treatment of conditions such as depression, addiction, or anxiety, a new study suggests.

12 Sep 2023

Specialized astrocyte subpopulation discovery sheds light on brain health and treatment avenues

In a recent study published in Nature, researchers investigated whether glutamatergic gliotransmission was mediated by specialized astrocytes in the central nervous system.

7 Sep 2023

New blood test pinpoints Parkinson's disease through mitochondrial DNA damage

Researchers have developed a new blood test that measures mitochondrial DNA damage as a potential marker for Parkinson's disease (PD). The study shows the test could aid in diagnosing PD and assessing responses to LRRK2 kinase inhibitors, which may help in reducing mitochondrial damage in PD patients.

4 Sep 2023

Could marine plasmalogens be the secret weapon to fight Alzheimer's and Parkinson's?

The research paper reviews the potential benefits of marine plasmalogens, a type of glycerophospholipid, in combating age-related diseases like Alzheimer's and Parkinson's. These compounds, abundant in marine resources, could improve lipid metabolism and reduce oxidative stress, offering a new avenue for improving the quality of life in aging populations.

3 Sep 2023

A review of the neurological imaging techniques in dementia diagnosis

Researchers reviewed existing data on the contribution of neuroimaging modalities such as magnetic resonance imaging.

28 Aug 2023

Dopaminergic News and Research

IDO2 deficiency in mice leads to behavioral abnormalities resembling autism spectrum disorder

Study deciphers how misfolded protein drives dopaminergic neuron loss in Parkinson's

Breakthrough in Parkinson's research: Scientists identify protein synthesis pathway as culprit

Kyoto scientists map double whammy gene clusters for anxiety disorders

Organoid model unveils secrets of the brain's dopaminergic system

Multi-ingredient herbal supplement boosts cognitive speed and gut health in seniors

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Breakthrough study: inhibiting USP30 gene offers hope in treating Parkinson’s disease

New research explores the unique effects of ADHD medications on Drosophila brain cells

Game-changer for Parkinson’s therapy: Innovative neuroprosthesis enhances mobility and balance

New gene therapy strategy shows promise for Parkinson's disease

Groundbreaking study reveals most effective adjunctive drug for Parkinson's disease

Hormones and high blood pressure: Study reveals endocrine culprits and targeted treatments

Parkinson's disease-related neuronal death more likely to occur at night

Study upends common belief in what triggers Parkinson's disease

Targeted use of ultrasound technology can lead to significant changes in brain function

Specialized astrocyte subpopulation discovery sheds light on brain health and treatment avenues

New blood test pinpoints Parkinson's disease through mitochondrial DNA damage

Could marine plasmalogens be the secret weapon to fight Alzheimer's and Parkinson's?

A review of the neurological imaging techniques in dementia diagnosis

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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