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New hope for advances in treatment methods for AIDS, Alzheimer's and age-related blindness

Pharmaceutical science leaders from the FDA, research institutions and top pharmaceutical companies will gather at the 2004 AAPS National Biotechnology Conference, AAPS' spring annual meeting.

4 May 2004

Cymbalta helped patients with depression feel better

Patients treated successfully with 60 mg per day of the investigational antidepressant Cymbalta® (duloxetine hydrochloride), were less likely to have their emotional and physical symptoms of depression return than those who stopped taking medication after beginning to feel better

3 May 2004

Elastic titanium nails help children recover faster from a broken leg than the traditional cast treatment

Elastic titanium nails help children recover faster from a broken leg than the traditional treatment with weeks of traction and a body cast, according to a new study from The Children's Hospital of Philadelphia.

3 May 2004

Intranasal influenza vaccine may help induce broader immunity in children than the traditional flu shot

MedImmune, Inc. has announced clinical data showing that a live, attenuated intranasal influenza vaccine (LAIV) may help induce broader immunity in children against drifted influenza strains when compared to the traditional flu shot (TIV).

2 May 2004

Morphine does not alleviate acute pain in preterm neonates

Preterm neonates undergo many painful procedures as part of their standard care in the Neonatal Intensive Care Unit (NICU). Preterm babies are able to experience pain and indeed are highly sensitive to it.

2 May 2004

Treatment for sleep apnea could save 980 lives and $11.1 billion each year

Each year, potentially 980 lives could be saved and $11.1 billion in automobile-accident costs could be avoided if drivers who suffer from a disorder called obstructive sleep apnea were successfully treated with continuous positive airway pressure (CPAP).

1 May 2004

Immunization back on agenda as whooping cough increases

Immunization for pertussis, also known as whooping cough, began in the mid-1940s and resulted in a sharp decline of this serious illness over the next 25 years. Over the last two decades, however, as immunity has waned, pertussis has re-emerged in the United States, with the greatest increase seen in adolescents, adults and young infants.

1 May 2004

Functional genomics and proteomics may accelerate the discovery of new drugs and therapeutic molecules

Functional genomics and proteomics have been quite successful in identifying functions of potential therapeutic targets such as encoded proteins. In fact, the possibilities of identifying more than 10,000 novel target antigens in the human genome may accelerate the discovery of new drugs and therapeutic molecules.

29 Apr 2004

Antiepileptic drug Levetiracetam may help patients with Parkinson's disease

In patients with Parkinson's disease, the antiepileptic drug levetiracetam (Keppra(R)) reduced the involuntary movements (dyskinesia) associated with levodopa, the medication most commonly used to treat Parkinson's disease, according to a study presented today at the 56th annual meeting of the American Academy of Neurology.

29 Apr 2004

Studies show pregabalin does not affect male reproductivity or interfere with oral contraceptives

Two studies presented today at the American Academy of Neurology (AAN) 56th Annual Meeting show that pregabalin, when used as an add-on treatment for epilepsy, does not affect male reproductive function or interfere with the effectiveness of oral contraceptives.

29 Apr 2004

Body repositioning is highly effective in resolving dizziness

Dizziness is one of the most common medical complaints affecting older adults, with 10-20 percent of such complaints resulting from Benign Paroxysmal Positional Vertigo (BPPV). Many research studies have stated that without medical treatment, some 30 percent of BPPV patients will recover on their own. Now, a new evidence-based review has found that a single ten minute in-office treatment, based on a series of head and body turns, is highly effective in resolving this disorder, with an overall effectiveness of 70-80 percent.

29 Apr 2004

Study shows MIRAPEX(R) (pramipexole) relieves patients with restless legs syndrome

Results from a large-scale, randomized, double-blind study show MIRAPEX(R) (pramipexole) provides rapid relief in patients with restless legs syndrome (RLS).

28 Apr 2004

FDA requires pancreatic extract manufacturers to get approval to remain on the market

The Food and Drug Administration (FDA) today formally notified manufacturers of pancreatic insufficiency products that these drugs must get approval by FDA within the next four years in order to remain on the market.

28 Apr 2004

Estimates vary, but as much as 20% of new prescriptions never get filled and 85% of refills never leave the pharmacy

Furthermore, a study conducted by the University of Arizona's School of Pharmacy finds that 40% of patients who receive outpatient drug therapy will experience a treatment failure or new medical problem as a result of improper use.

28 Apr 2004

$Untreated postmenopausal women with osteoporosis are at risk for first spinal fracture within one year$

Untreated postmenopausal women with osteoporosis are at risk for first spinal fracture within one year

Results of a new analysis found that, without treatment, one out of 13 postmenopausal osteoporotic women who were initially fracture-free were likely to experience a spinal fracture within one year.

28 Apr 2004

Inspire announces positive results in cystic fibrosis study

Inspire Pharmaceuticals, Inc. today announced top-line results in a Phase II study of INS37217 Respiratory in patients with mild cystic fibrosis (CF) lung disease.

27 Apr 2004

Parkinson’s disease drug Pergolide effective in treating restless legs syndrome

Pergolide, a drug commonly used to treat Parkinson’s disease symptoms, has recently been shown to be effective in treating restless legs syndrome. Researchers from seven countries collaborated on the study, published in the April 27 issue of Neurology, the scientific journal of the American Academy of Neurology.

26 Apr 2004

Overview of West Nile virus before season starts

West Nile virus is a newly emergent virus of the family Flaviviridae, found in both tropical and temperate regions. It mainly infects birds, but is also the cause of a number of conditions in humans, horses, and some other mammals. It is transmitted by bites of infected mosquitoes.

24 Apr 2004

The April 2004 issue of Otolaryngology focuses on head and neck surgery

The efficacy of a new cancer-fighting virus is tested in the study, “Treatment of Solid Sarcomas in Immunocompetent Mice with Novel Oncolytic Herpes Simplex Viruses.” A team of multi-disciplinary Japanese researchers found that a weakened version of herpes simplex virus (HSV) effectively eradicated neck and flank tumors in mice.

23 Apr 2004

GSK and WHO collaborate to fight malaria

GlaxoSmithKline (GSK), the World Health Organisation's Special Programme for Research and Training in Tropical Diseases (WHO-TDR) and the Medicines for Malaria Venture (MMV) today announced the signing of a collaborative agreement, to develop a new-fixed dose artemisinin combination therapy drug (ACT), combining chlorproguanil, dapsone and artesunate (CDA) for the treatment of malaria.

23 Apr 2004

Efficacy News and Research

New hope for advances in treatment methods for AIDS, Alzheimer's and age-related blindness

Cymbalta helped patients with depression feel better

Elastic titanium nails help children recover faster from a broken leg than the traditional cast treatment

Intranasal influenza vaccine may help induce broader immunity in children than the traditional flu shot

Morphine does not alleviate acute pain in preterm neonates

Treatment for sleep apnea could save 980 lives and $11.1 billion each year

Immunization back on agenda as whooping cough increases

Functional genomics and proteomics may accelerate the discovery of new drugs and therapeutic molecules

Antiepileptic drug Levetiracetam may help patients with Parkinson's disease

Studies show pregabalin does not affect male reproductivity or interfere with oral contraceptives

Body repositioning is highly effective in resolving dizziness

Study shows MIRAPEX(R) (pramipexole) relieves patients with restless legs syndrome

FDA requires pancreatic extract manufacturers to get approval to remain on the market

Estimates vary, but as much as 20% of new prescriptions never get filled and 85% of refills never leave the pharmacy

Untreated postmenopausal women with osteoporosis are at risk for first spinal fracture within one year

Inspire announces positive results in cystic fibrosis study

Parkinson’s disease drug Pergolide effective in treating restless legs syndrome

Overview of West Nile virus before season starts

The April 2004 issue of Otolaryngology focuses on head and neck surgery

GSK and WHO collaborate to fight malaria

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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