Efficacy News and Research

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DELiVR's virtual reality training speeds up cell detection in complex brain datasets

Efficient neuronal activity detection in brain imaging.

25 Apr 2024

Mandatory reporting laws meant to protect children get another look

More than 60 years ago, policymakers in Colorado embraced the idea that early intervention could prevent child abuse and save lives.

25 Apr 2024

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

25 Apr 2024

New system personalizes chemotherapy doses for cancer patients

When cancer patients undergo chemotherapy, the dose of most drugs is calculated based on the patient's body surface area. This is estimated by plugging the patient's height and weight into an equation, dating to 1916, that was formulated from data on just nine patients.

24 Apr 2024

Research reveals potential target for enfortumab vedotin therapy in urothelial carcinoma

Under the leadership of PD Dr. Niklas Klümper, Assistant Physician at the Department of Urology at the University Hospital Bonn (UKB) and Clinician Scientist of the BMBF-funded ACCENT program and PD Dr. Markus Eckstein, senior physician at the Institute of Pathology at the Uniklinikum Erlangen of the Friedrich-Alexander-University Erlangen-Nürnberg (FAU), an interdisciplinary research team has published new findings that indicate which patients with advanced urothelial carcinoma could benefit in particular from the new targeted therapy with the antibody-drug conjugate enfortumab vedotin.

24 Apr 2024

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

In a landmark study, an international consortium led by researchers at Children's Hospital of Philadelphia (CHOP) published the final results of a key clinical trial of the gene therapy CASGEVY (exagamglogene autotemcel) for the treatment of sickle cell disease in patients 12 years and older with recurrent vaso-occlusive crises (VOCs).

24 Apr 2024

New sustainable diagnostic approach offers precision cancer testing with minimal environmental impact

Accurate and cost-effective cancer detection.

24 Apr 2024

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Intranasal administration of neomycin sulfate in murine models shows promise as a prophylactic and therapeutic agent against respiratory viruses like influenza A and SARS-CoV-2 by inducing interferon-stimulated gene (ISG) expression, independent of microbiota and interferon activation.

24 Apr 2024

Research highlights best window for paxlovid administration in COVID-19 patients

Researchers have described the optimal timing for COVID-19 patients to take the antiviral, Paxlovid, to get the most benefit from the treatment, according to a study published April 16 in eLife.

23 Apr 2024

Investigating the efficacy and safety of existing drugs in patients with rare immune diseases

This month the first study within the DRIMID consortium (DRIMID stands for Drug Rediscovery for Rare Immune Mediated Inflammatory Diseases) has started.

23 Apr 2024

Innovative malaria prodrug targets liver, enhances efficacy while reducing toxicity, preclinical studies show

Tafenoquine, a prodrug that could fulfill the criteria for a mass eradication campaign.

23 Apr 2024

CN Bio raises $21 million USD in first close of Series B investment round

Bayland Capital and founding shareholder, CN Innovations Holdings Ltd, to invest $10 M and $5.5 M, respectively. Investment will expand product development and scaling of the organization to meet increased demand for Organ-on-a-Chip (OOC) solutions.

23 Apr 2024

Review: Facilitators and barriers to vaccination uptake in pregnancy

Researchers from St George’s, University of London have identified key barriers to vaccine uptake for whooping cough, flu and Covid-19 in pregnant women, and outline recommendations for addressing vaccine hesitancy. The results are from the first review of its kind and published today in the journal PLOS ONE.

23 Apr 2024

Academic pressure linked to higher depression risk in teens

A study in The Lancet Child & Adolescent Health links academic achievement goals to increased risk of depression in adolescents, suggesting that the pressure to outperform peers may heighten depressive symptoms.

22 Apr 2024

AI models fall short in medical coding accuracy

State-of-the-art artificial intelligence systems known as large language models (LLMs) are poor medical coders, according to researchers at the Icahn School of Medicine at Mount Sinai.

22 Apr 2024

Top pharmaceutical company evaluates Optimer for precision liver medicine

Optimer delivery vehicle has been shipped to a pharma partner for external evaluation.

From Aptamer Group 22 Apr 2024

Korean fermented food Doenjang shows promise in alleviating menopausal symptoms

Study compares the effects of traditional versus commercial Korean Doenjang on menopausal symptoms, finding that traditional variants with high beneficial microorganisms are more effective in reducing these symptoms and improving cardiovascular and gut health.

21 Apr 2024

Efficacy News and Research

DELiVR's virtual reality training speeds up cell detection in complex brain datasets

Mandatory reporting laws meant to protect children get another look

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

New system personalizes chemotherapy doses for cancer patients

Research reveals potential target for enfortumab vedotin therapy in urothelial carcinoma

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

New sustainable diagnostic approach offers precision cancer testing with minimal environmental impact

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Research highlights best window for paxlovid administration in COVID-19 patients

Investigating the efficacy and safety of existing drugs in patients with rare immune diseases

Innovative malaria prodrug targets liver, enhances efficacy while reducing toxicity, preclinical studies show

CN Bio raises $21 million USD in first close of Series B investment round

Review: Facilitators and barriers to vaccination uptake in pregnancy

Academic pressure linked to higher depression risk in teens

AI models fall short in medical coding accuracy

Top pharmaceutical company evaluates Optimer for precision liver medicine

Korean fermented food Doenjang shows promise in alleviating menopausal symptoms

Cruciferous vegetables may offer new hope for inflammatory bowel disease management

MONET: New AI tool enhances medical imaging with deep learning and text analysis

New AI tool 'TORCH' successfully identifies cancer origins in unknown primary cases

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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