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Structural study identifies target for broad-spectrum antivirals against herpesviruses

Human herpesviruses comprise the alpha, beta, and gamma subfamilies and are a widely prevalent group of DNA-enveloped viruses, capable of establishing lifelong latent infections in humans and causing various diseases.

26 Feb 2024

Red light therapy shown to significantly reduce blood sugar spikes, study finds

Using red light of 670 nm wavelength impacted the circulating glucose levels in the plasma, using oral glucose tolerance tests.

23 Feb 2024

Yale chemists synthesize complex anticancer molecules from marine invertebrates

Nearly 30 years ago, scientists discovered a unique class of anticancer molecules in a family of bryozoans, a phylum of marine invertebrates found in tropical waters.

22 Feb 2024

Researchers discover mechanism to reverse amyloid plaque assembly in Alzheimer's disease

University of North Carolina at Chapel Hill researchers have developed a new drug delivery platform that harnesses helical amyloid fibers designed to untwist and release drugs in response to body temperatures.

22 Feb 2024

Study reveals novel mechanism for longevity of oocytes

Oocytes are immature egg cells that develop in almost all female mammals before birth. The propagation of future generations depends on this finite reserve of cells surviving for many years without incurring damage.

20 Feb 2024

Maternal mRNA COVID-19 vaccination shields infants for six months

Women who receive an mRNA-based COVID-19 vaccination or booster during pregnancy can provide their infants with strong protection against symptomatic COVID-19 infection for at least six months after birth, according to a study from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

15 Feb 2024

$Novel "Flash and Freeze-fracture" technique reveals neuronal communication secrets$

Novel "Flash and Freeze-fracture" technique reveals neuronal communication secrets

Fear and addiction exert significant influence within society. Managing them is often challenging, as they are driven by intricate neuronal circuits in our brains.

14 Feb 2024

How does melanin distribution impact UV damage?

How melanin content and distribution affect ultraviolet damage in skin.

14 Feb 2024

Study reveals role of protein modification in neurodegenerative disease progression

Neurodegenerative diseases, such as Alzheimer's and Parkinson's, present a significant health challenge, affecting over 50 million people globally.

12 Feb 2024

Wayne State researchers secure $1.4 million DoD grant for prostate cancer study

A team of researchers from Wayne State University was awarded a $1.4 million, three-year grant from the U.S. Department of Defense for the study, "Cytochrome c acetylation drives prostate cancer aggressiveness and Warburg effect."

7 Feb 2024

Unraveling the architecture of poxvirus cores

A recent re-emergence and outbreak of Mpox brought poxviruses back as a public health threat, underlining an important knowledge gap at their core.

6 Feb 2024

Unveiling HIV's "latch": New study reveals key to blocking infection

As the HIV virus glides up outside a human cell to dock and possibly inject its deadly cargo of genetic code, there's a spectacularly brief moment in which a tiny piece of its surface snaps open to begin the process of infection.

2 Feb 2024

Scientists discover orderly structure hidden within bacterial biofilms

Bacteria are traditionally imagined as single-cell organisms, spread out sparsely over surfaces or suspended in liquids, but in many environments the true bacterial mode of growth is in sticky clusters called biofilms.

2 Feb 2024

Study reveals key mechanism behind obesity-related metabolic dysfunction

Researchers found that feeding a high-fat diet (HFD) causes mitochondrial dysfunction and fragmentation in white adipocytes in mice.

31 Jan 2024

HIV virus found to possess hidden transport ability

Around one million individuals worldwide become infected with HIV, the virus that causes AIDS, each year.

27 Jan 2024

CRISPR off-switch discovered: Safer gene editing for future therapies

Using CRISPR, an immune system bacteria use to protect themselves from viruses, scientists have harnessed the power to edit genetic information within cells.

19 Jan 2024

New study reveals flaws in AI tools used for SARS-CoV-2 antibody discovery

A discovery program for SARS-CoV-2-nABs potentially targeting its resistant strains.

19 Jan 2024

New structural insights pave the way for drug-resistant malaria therapies

Structural insights into a potent antimalarial drug candidate's interaction with the malaria parasite Plasmodium falciparum have paved the way for drug-resistant malaria therapies, according to a new study by researchers at Weill Cornell Medicine and Van Andel Institute.

18 Jan 2024

St. Jude announces $13 million investment to expand the understanding of G-protein coupled receptors

St. Jude Children's Research Hospital today announced a nearly $13 million investment toward a new research collaboration with scientists at Columbia University, Duke University and Stanford University to expand the understanding of G-protein coupled receptors (GPCR), which are vital proteins that impact human health and disease.

18 Jan 2024

Monkey study points to HIV vulnerability for vaccine attack

Three different HIV antibodies each independently protected monkeys from acquiring simian-HIV (SHIV) in a placebo-controlled proof-of-concept study intended to inform development of a preventive HIV vaccine for people.

17 Jan 2024