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Are we as crazy as mad cows?

When proteins in our body work properly, we can see, smell, consume and digest food, grow muscle and brain cells. But when these infinitely useful biological building blocks fail, the most pernicious diseases arise. Susan Lindquist has scrutinized the complex origami-like shapes of proteins and come to understand how structural mistakes can lead to a frightening class of neurodegenerative disorders, including “Mad Cow Disease.”

20 May 2004

Natural biological process by which yeast cells dismantle amyloid fibers

Amyloid fibers, those clumps of plaque-like proteins that clog up the brains of Alzheimer's patients, have perplexed scientists with their robust structures. In laboratory experiments, they are able to withstand extreme heat and cold and powerful detergents that cripple most other proteins.

20 May 2004

Scientists have sped up a common jumping gene found in the human genome

Johns Hopkins scientists have transformed a common "jumping gene" found in the human genome into one that moves hundreds of times more often than normal in mouse and human cells.

20 May 2004

Matching method allows surgeons to successfully transplant kidneys that would otherwise be discarded

By carefully matching the estimated function of kidneys from deceased donors with the needs of potential recipients, surgeons can successfully transplant kidneys that would otherwise be discarded, according to a report from Wake Forest University Baptist Medical Center. The center was able to double its transplant volume within a year.

18 May 2004

Study helps to visualize how brain develops with age

The brain's center of reasoning and problem solving is among the last to mature, a new study graphically reveals. The decade-long magnetic resonance imaging (MRI) study of normal brain development, from ages 4 to 21, by researchers at NIH's National Institute of Mental Health (NIMH) and University of California Los Angeles (UCLA) shows that such "higher-order" brain centers, such as the prefrontal cortex, don't fully develop until young adulthood.

18 May 2004

Want a new type of man? Maybe less brawn and more brains?

A new version of the human male is a distinct possibility, given the genetic erosion of the “junk” sex-determining chromosome that makes men male.

17 May 2004

Researchers identify new genes that control the formation of cilia found throughout the human body

Howard Hughes Medical Institute researchers have used a combination of brainpower and computer power to identify a multitude of new genes that control the formation of tiny, hair-like cilia that stipple the surfaces of many organs in a wide variety of creatures.

14 May 2004

Biochip technology to revolutionise the pharmaceutical industry

Advancements in biotechnology have culminated in its integration with semiconductor technologies such as micro-electromechanical systems, resulting in the evolution of biochips. Biochips provide pharma companies with sophisticated tools for speedy development of drugs and accurate diagnosis and understanding of biological mechanisms.

13 May 2004

Scientists discover what could be the instruction manual of life

In a world first, scientists from The University of Queensland’s Institute for Molecular Bioscience (IMB) have uncovered a new class of genetic elements with the potential to radically alter our notions of how the genome “comes to life” to form humans.

8 May 2004

Research uncovers critical pieces of human genome

Researchers have found precisely the same sequences in the genomes of humans, rats, and mice; sequences that are 95 to 99 percent identical to these can be found in the chicken and dog genomes, as well.

6 May 2004

World's first gene therapy trial aimed at preventing cancer

The concept seems straightforward. If, at its heart, cancer is a disease of genes, then giving patients new genes should disarm cancer. Such treatment would replace missing or faulty genes that keep cell growth in check, or would flush the body with "super genes" that could attack and destroy cancer.

5 May 2004

New technique of identifying genes may help researchers developing drugs

A quick new technique able to identify genes that evolve rapidly as well as those that change slowly already has pinpointed new targets for researchers developing drugs against tuberculosis and malaria, and it could do the same for other infectious diseases, according to a paper in this week's Nature.

29 Apr 2004

Carbohydrate-binding proteins are becoming extremely useful in curing various illnesses

Researchers are beginning to see the potential for breakthrough in healthcare through glycomics, which studies carbohydrates, proteins and their interactions. In fact, these carbohydrates are moving beyond their regular roles as sugar storage bins.

28 Apr 2004

A high rate of marriage among deaf individuals can explain the increased frequency of connexin deafness in the United States

A high rate of marriage among deaf individuals can explain the increased frequency of connexin deafness in the United States and may have led to a doubling of its occurrence during the past 200 years, according to a study by hereditary deafness experts at Virginia Commonwealth University.

27 Apr 2004

Severe Acute Respiratory Syndrome (SARS) overview

Severe Acute Respiratory Syndrome (SARS) is an atypical form of pneumonia that first appeared in November 2002 in Guangdong Province, China.

24 Apr 2004

Pierre Pettigrew outlines plan of action for health care reforms

Canadians have a "right" to know how long they have to wait to receive medical treatment, Health Minister Pierre Pettigrew said yesterday.

21 Apr 2004

Human cloning on a grand scale could spell the end of the species as we all become nastier

Human cloning on a grand scale could spell the end of the species as we all become nastier, warn researchers at the University of Sussex.

20 Apr 2004

Genetic connection between humans, mice and dogs

The discovery that humans are genetically close to mice and dogs might make people develop greater respect for life, J. Craig Venter, a major contributor to the historic mapping of the human genome, said.

16 Apr 2004

There is more to beauty than meets the stranger's eye

There is more to beauty than meets the stranger's eye, according to results from three studies examining the influence of non-physical traits on people's perception of physical attractiveness.

16 Apr 2004

Extensive gene traffic, the process of genes leaving and arriving on the chromosome

Researchers at the University of Chicago have discovered there is extensive gene “traffic”—the process of genes leaving and arriving on the chromosome—on the mammalian X chromosome. They also have overturned a conventional theory about how genes evolved on the sex chromosome.

16 Apr 2004