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AI-MARRVEL: A leap forward in diagnosing genetic diseases with over 98% precision

The knowledge-driven MARRVEL AI-based model (AIM) to identify Mendelian illnesses.

30 Apr 2024

Asimov achieves 10x improvement in lentiviral production, launches new stable cell line development service

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30 Apr 2024

Psychedelic compound shows promise in stress relief for socially aggressive mice

A study in Neuropharmacology reveals that a single dose of the psychedelic compound (R)-DOI significantly improves stress-coping behaviors and reduces inflammatory markers in mice subjected to social aggression.

30 Apr 2024

Study: Healthy lifestyle may reduce impact of life-shortening genes

A healthy lifestyle may offset the effects of life-shortening genes by more than 60%, suggests an analysis of the findings from several large long term studies, published online in the journal BMJ Evidence Based Medicine.

29 Apr 2024

New Kaposi sarcoma mouse model could be key to drug development

Researchers at UNC Lineberger Comprehensive Cancer Center, after decades of research efforts, have developed a mouse model of Kaposi sarcoma that could be key to the development of new drugs to treat the disease.

29 Apr 2024

Study reveals genetic divergence and drug resistance mechanisms in two critical superbugs

Infectious diseases caused by pathogenic strains of bacteria are a global cause of morbidity and mortality. Hospital-acquired infections caused by Klebsiella pneumonia and Pseudomonas aeruginosa were found vulnerable during the COVID-19 pandemic.

29 Apr 2024

Genetic associations of key genes in breast cancer pathogenesis

Breast cancer remains a significant global health concern, warranting further exploration into its genetic basis and potential therapeutic targets.

29 Apr 2024

Unlocking the mechanisms of pluripotent cell's fate determination

As embryos, all complex organisms are partially made up of pluripotent stem cells, a term for cells that have the capacity to differentiate into any kind of cell: nerve cells, muscle cells, blood cells, skin cells, and the like.

29 Apr 2024

Renewed classification of primary iron overload syndromes based on Hep25/FP system

The clinical introduction of hepcidin25 (Hep25) has led to a more detailed understanding of its relationship with ferroportin (FP) and divalent metal transporter1 in primary iron overload syndromes (PIOSs).

29 Apr 2024

New study reveals potential cellular mechanism behind cognitive decline in Alzheimer's

Researchers have developed a robust method for identifying rare brain neurons that re-enter the cell cycle, offering insights into their role in cognitive disorders such as Alzheimer's disease.

28 Apr 2024

Harnessing immune enhancement to combat drug-resistant tuberculosis

Experts are working on novel immune-enhancing therapies called host-directed therapies to use the body's own immune system to target tuberculosis, with hopes that they could tackle even the drug-resistant forms of the disease.

26 Apr 2024

Leveraging CRISPR/Cas technology to address antimicrobial resistance

In the second new research review on this subject, Assistant Prof. Ibrahim Bitar, Department of Microbiology, Faculty of Medicine and University Hospital in Plzen, Charles University in Prague, Plzen, Czech Republic, will give an overview of the molecular biology of CRISPR technology in explaining how it can used to tackle antimicrobial resistance.

26 Apr 2024

Largest study of BRCA1 and BRCA2 carriers refines cancer risk estimates in Asian population

A team of clinician-scientists and scientists from the University of Nottingham (Malaysia campus), National Cancer Centre Singapore (NCCS), Cancer Research Malaysia, Nanyang Technological University, Singapore (NTU Singapore), University of Malaya, University of Cambridge, A*STAR's Genome Institute of Singapore (GIS) and other institutions, have conducted the largest study done to date of BRCA1 and BRCA2 (BReast CAncer Gene 1 and 2) carriers in an Asian population and refined breast and ovarian cancer risk estimates for this population.

26 Apr 2024

Genes News and Research

AI-MARRVEL: A leap forward in diagnosing genetic diseases with over 98% precision

Asimov achieves 10x improvement in lentiviral production, launches new stable cell line development service

Psychedelic compound shows promise in stress relief for socially aggressive mice

Study: Healthy lifestyle may reduce impact of life-shortening genes

New Kaposi sarcoma mouse model could be key to drug development

Study reveals genetic divergence and drug resistance mechanisms in two critical superbugs

Genetic associations of key genes in breast cancer pathogenesis

Unlocking the mechanisms of pluripotent cell's fate determination

Renewed classification of primary iron overload syndromes based on Hep25/FP system

New study reveals potential cellular mechanism behind cognitive decline in Alzheimer's

Harnessing immune enhancement to combat drug-resistant tuberculosis

Leveraging CRISPR/Cas technology to address antimicrobial resistance

Largest study of BRCA1 and BRCA2 carriers refines cancer risk estimates in Asian population

Study suggests lingering coronavirus in tissues may contribute to long COVID symptoms

How body shape influences colorectal cancer risk

Scientists identify signaling pathway in liver cells linked to fibrosis

Yeast study reveals evolutionary history of iron uptake mechanisms

Synthetic nanomaterial could be an effective tool for treating neurodegenerative diseases

MIT study reveals circadian impact on drug metabolism in engineered livers

Multi-omics approach powers Karolinska Institutet's Single Cell Atlas

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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