Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

Understanding the role played by HIV in pulmonary hypertension

Across the globe, more than 39 million people are living with the Human Immunodeficiency Virus (HIV), the virus that causes AIDS, including more than 1.3 million new HIV diagnoses last year.

23 Feb 2024

Females' immune system edges out males but at a cost of higher autoimmune risk

A review article highlights how two X chromosomes in females influence immune system composition and function, leading to faster infection clearance and stronger vaccination responses but also a higher risk of autoimmune diseases.

22 Feb 2024

Scripps Research scientists develop an antibody that blocks lethal snake toxins

Scripps Research scientists have developed an antibody that can block the effects of lethal toxins in the venoms of a wide variety of snakes found throughout Africa, Asia and Australia.

21 Feb 2024

Individual genetic variations and bacterial flora linked to recurrent caries disease

Researchers at Umeå University have for the first time been able to show that individual variation in susceptibility to infection and bacterial flora together explain recurrent caries disease and that others are asymptomatic.

21 Feb 2024

Researchers develop novel nanomedicine loaded with genetic material to fight HIV

Society learned about the value of mRNA during the COVID-19 pandemic when we saw scientists and medical professionals harness its power to deliver a vaccine for the virus within a year.

20 Feb 2024

Combination therapy shows promise in targeting latent HIV reservoirs

Antiretroviral therapies (ART) stop HIV replication in its tracks, allowing people with HIV to live relatively normal lives.

15 Feb 2024

U of M research offers new avenue of hope in the fight against chronic HIV

Published in the Journal of Infectious Diseases Oxford Academic, research led by the University of Minnesota Medical School offers a new avenue of hope in the fight against chronic human immunodeficiency virus (HIV) infection.

14 Feb 2024

Vaccines safe for pregnant women with HIV but show reduced immune response

A meta-analysis in eClinicalMedicine finds vaccines are safe for pregnant women living with HIV, showing reduced immunogenicity compared to those without HIV but no increase in adverse events, highlighting the need for their inclusion in vaccine trials.

9 Feb 2024

Paxlovid enhances treatment options for COVID-19 patients

The design, synthesis, and mechanism of action of Paxlovid.

6 Feb 2024

Syphilis: A silent epidemic reawakens

Study reports a significant increase in syphilis cases in India, highlighting the need for effective prevention and treatment despite the availability of effective therapies.

31 Jan 2024

Immunocompromised patients show prolonged SARS-CoV-2 infection and unique mutations

study identifies risk factors for prolonged SARS-CoV-2 infection in immunocompromised patients, revealing that B-cell dysfunction, solid organ transplantation, and AIDS lead to longer infections and unique spike mutations.

31 Jan 2024

HIV virus found to possess hidden transport ability

Around one million individuals worldwide become infected with HIV, the virus that causes AIDS, each year.

27 Jan 2024

Do yellow fever vaccines truly provide effective lifelong protection against the disease after a single dose?

The long-term protection offered by one dose of vaccine against yellow fever.

25 Jan 2024

Study addresses knowledge gap of clinical features and outcomes of Black patients with melanoma

Researchers identified patient- and tumor-level melanoma features in black individuals.

25 Jan 2024

New study reveals key tissues involved in HIV rebound after treatment

In findings that have implications for potential new HIV therapies, researchers from Texas Biomedical Research Institute (Texas Biomed) used genetic sequencing techniques on the nonhuman primate version of the virus to identify that lymph nodes in the abdomen are the leading source of rebound infection after the first week of stopping antiretroviral treatment.

24 Jan 2024