Interferon News and Research

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Heart at risk from ARDS: Inflammatory responses fuel cardiovascular complications

Research highlights the inflammatory impacts of ARDS on the heart, underscoring the role of immune responses in cardiovascular complications from viral infections, including COVID-19, and emphasizes the potential of TNF-α neutralizing therapy to mitigate these effects.

24 Mar 2024

Lactate's role in driving cancer cachexia uncovered

Study highlights the significant role of lactate in promoting cancer cachexia via activation of the adipose-specific G-protein-coupled receptor 81 (GPR81), suggesting new therapeutic targets for this condition.

20 Mar 2024

Genetic key to milder COVID: Certain genes slash severity and death risk in older men

Study found that certain genetic variants in the IL1RN gene significantly reduce COVID-19-related inflammation and mortality in patients, with notable improvements observed in older men carrying specific single-nucleotide variants.

19 Mar 2024

Understanding long COVID: A call for better diagnosis and treatment

A recent review in Nature Reviews Microbiology summarizes the complex mechanisms, significant impacts, and the urgent need for enhanced diagnostics and treatments for long COVID, affecting over 65 million people globally with diverse, debilitating symptoms and systemic health issues.

7 Mar 2024

New class of antiviral drugs could shield against future viral outbreaks

A University of Alberta research team has uncovered a new class of drugs with the potential to prevent or treat infections in a future viral outbreak.

4 Mar 2024

Innovative therapy targets and destroys leukemia stem cells

Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States, have devised an innovative approach to target and destroy hard-to-kill leukemia stem cells.

26 Feb 2024

Identifying antiviral protein IFN-γ as a potential biomarker for Long COVID

SARS-CoV-2 triggers the production of the antiviral protein IFN-γ, which is associated with fatigue, muscle ache and depression. New research shows that in Long COVID patients, IFN-y production persists until symptoms improve, highlighting a potential biomarker and a target for therapies.

24 Feb 2024

Elevated IFN-γ levels linked to long COVID, study finds

Researchers find elevated IFN-γ levels in long COVID patients, with symptom improvement correlating with decreased IFN-γ, suggesting it as a potential biomarker and target for therapeutic intervention.

22 Feb 2024

Novel treatment for polycythemia vera shows promise in clinical trial

A novel treatment for polycythemia vera, a potentially fatal blood cancer, demonstrated the ability to control overproduction of red blood cells, the hallmark of this malignancy and many of its debilitating symptoms in a multi-center clinical trial led by the Icahn School of Medicine at Mount Sinai.

21 Feb 2024

COVID-19's neurological effects linked to immune response, not direct viral attack

Study identifies neurocognitive symptoms in COVID-19 patients as a reaction to systemic infection rather than direct brain infection, highlighting changes in the brain's immune response and synaptic organization.

21 Feb 2024

CPRIT awards MD Anderson 16 grants to support cancer research and prevention

The University of Texas MD Anderson Cancer Center today was awarded 16 grants totaling over $25.5 million from the Cancer Prevention and Research Institute of Texas (CPRIT) in support of cancer screening, early detection and prevention programs, faculty recruitment, and groundbreaking cancer research across all areas of the institution.

21 Feb 2024

Study highlights an immunological mechanism underlying Long COVID

SARS-CoV-2 triggers the production of the antiviral protein IFN-γ, which is associated with fatigue, muscle ache and depression.

21 Feb 2024

Study suggests patients with severe long COVID present with variable symptoms, do not cluster in relation to organs affected or immunological states

A new preprint reports significantly associated findings that may help predict severe long COVID and understand what causes it.

16 Feb 2024

COVID-19 impacts the brain through body inflammation, research finds

Scientists still are not sure how neurological symptoms arise in COVID-19. Is it because SARS-CoV-2 infects the brain? Or are these symptoms the result of inflammation in the rest of the body?

16 Feb 2024

Combo of targeted and immunotherapy may boost NSCLC treatment by overcoming immune resistance and enhancing anti-tumor activity

Researchers evaluated rational combination treatment regimens for advanced/metastatic non-small-cell lung cancer (NSCLC).

15 Feb 2024

Interferon News and Research

Heart at risk from ARDS: Inflammatory responses fuel cardiovascular complications

Lactate's role in driving cancer cachexia uncovered

Genetic key to milder COVID: Certain genes slash severity and death risk in older men

Understanding long COVID: A call for better diagnosis and treatment

New class of antiviral drugs could shield against future viral outbreaks

Innovative therapy targets and destroys leukemia stem cells

Identifying antiviral protein IFN-γ as a potential biomarker for Long COVID

Elevated IFN-γ levels linked to long COVID, study finds

Novel treatment for polycythemia vera shows promise in clinical trial

COVID-19's neurological effects linked to immune response, not direct viral attack

CPRIT awards MD Anderson 16 grants to support cancer research and prevention

Study highlights an immunological mechanism underlying Long COVID

Study suggests patients with severe long COVID present with variable symptoms, do not cluster in relation to organs affected or immunological states

COVID-19 impacts the brain through body inflammation, research finds

Combo of targeted and immunotherapy may boost NSCLC treatment by overcoming immune resistance and enhancing anti-tumor activity

Smoking, infection, and BMI found to significantly sway immune response, study shows

Cytokine interferon-gamma can be a disease-modifying therapeutic target in multiple system atrophy

Circulatory cholesterol levels are inversely linked to mortality of patients with sepsis and critical illness

Curcumin spray shows promise in fighting SARS-CoV-2 and flu viruses

Study provides valuable insights into the evolutionary dynamics of hepatitis E virus

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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