Leptin News and Research

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Leptin is a 16 kDa protein hormone that plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. It is one of the most important adipose derived hormones. The ''Ob(Lep)'' gene (Ob for obese, Lep for leptin) is located on chromosome 7 in humans.

UCD researcher receives ERC Consolidator grant to unlock computational insights into cardiac xenotransplantation

Dr Philip Cardiff, Associate Professor at University College Dublin's School of Mechanical and Materials Engineering, has received a European Research Council (ERC) Consolidator grant of €2 million for his 5-year project XenoSim.

1 Jun 2023

COVID-19 'bites the apple': Abdominal obesity ignites cytokine storm

Abdominal obesity increases the risk of severe COVID-19 and mortality due to heightened inflammatory responses, according to a study on Japanese patients and a murine COVID-19 model. Blocking inflammatory cytokines and preventing obesity may improve survival rates.

24 May 2023

Consuming ultra-processed foods is associated with an increased risk of developing non-alcoholic fatty liver disease

Researchers determined the contribution of ultra-processed food intake to the risk of developing NAFLD.

12 May 2023

Boosting gut health with short-chain fatty acids

Research paper provides an overview of short-chain fatty acids (SCFAs) and their role in regulating gut homeostasis. It also discusses SCFA-producing bacteria and potential therapeutic approaches to boost SCFA levels in the gut to treat related diseases.

9 May 2023

High-fat diets' eye-opening impact: Study reveals link to retinal damage and bisretinoid accumulation

In this study, the effects of a high-fat diet on the formation of bisretinoids in photoreceptor cells were explored. The results showed that mice on a high-fat diet had increased levels of bisretinoids and retinol-binding protein 4, which are associated with metabolic dysregulation.

8 May 2023

Insights from experts on the neurobiological processes involved in appetite regulation

Researchers summarized the main findings related to the neurobiological regulation of appetite presented at the 23rd Harvard Nutrition Obesity Symposium in June 2022.

8 May 2023

Examining the interplay between diet, glucose metabolism and sleep

Researchers summarized the inter-relationship between diet, glucose metabolism, and sleep.

2 May 2023

Study finds increased prevalence of hypertension among people with severe obesity and a genetic variant

Obesity and its associated cardiometabolic issues are a major health concern in the U.S. and internationally.

19 Apr 2023

Mouse studies can help find better therapeutic targets for people with PCOS

Polycystic ovarian syndrome, or PCOS, can cause a range of symptoms, including disrupted menstrual cycles, abdominal obesity, cardiovascular disease, and type 2 diabetes.

18 Apr 2023

Is there a correlation between acute and chronic red wine intake and health?

Researchers examined the correlations between acute and chronic red wine (RW) intake and health.

18 Apr 2023

Study finds sugary beverages increase dementia risk, while natural juices may help prevent it

Sugary beverages were associated with a higher risk of dementia, whereas moderate intake of natural juices was associated with a lower dementia risk.

17 Apr 2023

Factors shaping maternal gut microbiome during pregnancy and the impact on infant health

In an article published in the journal Current Opinion in Microbiology, scientists have provided a detailed overview of the factors affecting maternal gut microbiota during pregnancy and its impact on maternal and infant health.

17 Apr 2023

Pathophysiology, comorbidities, and interventions related to childhood obesity

Researchers discuss the psychological and physiological impacts of obesity on children.

6 Apr 2023

The impact of perinatal low-calorie sweetener exposure on the development of neural systems involved in metabolic regulation

A study published in the Journal of Clinical Investigation Insight reveals that consumption of low-calorie sweeteners during pregnancy can affect the metabolism and neural development of the offspring.

6 Apr 2023

Birth weight and maternal BMI modify the relationship between obesity and mortality rate

Obesity is a significant risk factor for premature mortality due to the predisposition to metabolic and cardiovascular disease. However, is this effect independent of the birth weight? A new research paper examines this aspect of adult obesity, measuring the effect of parental body mass index (BMI) and birth weight on the mortality risk.

3 Apr 2023

Can the Mediterranean diet and physical exercise improve the quality of life for cancer patients?

Researchers reviewed existing literature on the benefits of adopting Mediterranean diets against inflammatory conditions and cancer.

3 Apr 2023

Researcher hypothesizes that overnutrition could lead to loss of self-tolerance by impinging on immune regulation

Researchers explored the correlation between autoimmunity and obesity.

3 Apr 2023

New microscopy method illuminates the mechanics of embryo development

In 1922, French physicist Léon Brillouin predicted an interesting phenomenon – when light is shone on a material, it interacts with the naturally occurring thermal vibrations within it, exchanging some energy in the process.

30 Mar 2023

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Study outlines molecular mechanisms to aid the development of new therapies to manage obesity and associated health disorders.

29 Mar 2023

Maternal weight gain in pregnancy linked to children's risk of neurodevelopmental disorders

In a recent study published in the BMC Medicine journal, researchers in Sweden explored the association between above-optimal maternal gestational weight gain (GWG) and the risk of neurodevelopmental disorders such as intellectual disability, autism spectrum disorder (ASD), and attention-deficit/hyperactivity disorder (ADHD) in offspring.

29 Mar 2023

Leptin News and Research

Further Reading

UCD researcher receives ERC Consolidator grant to unlock computational insights into cardiac xenotransplantation

COVID-19 'bites the apple': Abdominal obesity ignites cytokine storm

Consuming ultra-processed foods is associated with an increased risk of developing non-alcoholic fatty liver disease

Boosting gut health with short-chain fatty acids

High-fat diets' eye-opening impact: Study reveals link to retinal damage and bisretinoid accumulation

Insights from experts on the neurobiological processes involved in appetite regulation

Examining the interplay between diet, glucose metabolism and sleep

Study finds increased prevalence of hypertension among people with severe obesity and a genetic variant

Mouse studies can help find better therapeutic targets for people with PCOS

Is there a correlation between acute and chronic red wine intake and health?

Study finds sugary beverages increase dementia risk, while natural juices may help prevent it

Factors shaping maternal gut microbiome during pregnancy and the impact on infant health

Pathophysiology, comorbidities, and interventions related to childhood obesity

The impact of perinatal low-calorie sweetener exposure on the development of neural systems involved in metabolic regulation

Birth weight and maternal BMI modify the relationship between obesity and mortality rate

Can the Mediterranean diet and physical exercise improve the quality of life for cancer patients?

Researcher hypothesizes that overnutrition could lead to loss of self-tolerance by impinging on immune regulation

New microscopy method illuminates the mechanics of embryo development

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Maternal weight gain in pregnancy linked to children's risk of neurodevelopmental disorders

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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