Leptin News and Research

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Leptin is a 16 kDa protein hormone that plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. It is one of the most important adipose derived hormones. The ''Ob(Lep)'' gene (Ob for obese, Lep for leptin) is located on chromosome 7 in humans.

Research suggests that lack of sleep may be contributing to the obesity pandemic

The recent rise in obesity may be partly due to the reduced amount of time we spend asleep, according to new research from the University of Bristol, UK.

6 Dec 2004

Battle of Waterloo could help doctors fight death from multiple organ failure

Waterloo’s battlefield is reigniting the debate about whether modern medicine is always good for you, according to University College London (UCL) scientists who are launching a study of why some critically ill patients recover and others die from multiple organ failure - the number one killer of patients in intensive care.

23 Nov 2004

Shp2 protein plays a critical role in obesity

A team of researchers led by The Burnham Institute's Gen-Sheng Feng, Ph.D. has discovered that a protein called Shp2 plays a critical role in obesity.

11 Nov 2004

Brain protein called MC4R that plays a role in the urge to eat has now been found to influence appetite in a second way

A brain protein already known to play a central role in the "feast or fast" signaling that controls the urge to eat has now been found to influence appetite in a second way. The discovery identifies a potential new target for drugs against obesity.

19 Oct 2004

Hormone leptin could play a key role in treating bone loss, anorexia and infertility in women

A new study has found that the hormone leptin plays a key role in women’s reproductive and neuroendocrine health and suggests a future for the hormone in treating a number of conditions including exercise-induced bone loss, anorexia and in some cases of infertility.

2 Sep 2004

Switches in the brain that tell the body to stop eating and start burning calories

A Brown-led research team has discovered a pair of universal switches in the brain that tell the body to stop eating and start burning calories.

3 Aug 2004

Leptin's fat-burning role in humans

For nearly a decade, scientists have known that leptin plays an important fat-burning role in humans. But the map of leptin's path through the body – the key to understanding how and why the hormone works – is still incomplete.

27 Jul 2004

U-M scientists say Wnt protein prevents obesity by inhibiting fat cell development

Genetically engineered mice, created at the University of Michigan Medical School, are living every dieter's dream.

29 Jun 2004

RNA enzyme research may lead to ways of monitoring fat metabolism and might even assist in the search for signs of life on Mars

Research aimed at teasing apart the workings of RNA enzymes eventually may lead to ways of monitoring fat metabolism and might even assist in the search for signs of life on Mars, according to University of Michigan researcher Nils Walter.

29 Jun 2004

Nighttime surge of ghrelin may point to new targets for treating obesity

UCLA scientists have discovered that lean people experience a huge nighttime surge of ghrelin — the hormone that stimulates hunger — but obese people do not.

29 Jun 2004

Fat hormone leptin affects a specific type of target neurons in the brain

Nina Balthasar and her colleagues have presented direct evidence that the fat hormone leptin affects a specific type of target neurons in the brain -- a prime link in the brain's regulation of the body's energy balance.

24 Jun 2004

Stimulation or drugs that target the pro-opiomelanocortin system will be effective in treating diabetes or obesity

There’s more than one way to slim a cat - at least that’s the hope of University of Florida obesity researchers, who believe pets and even people may someday benefit from gene therapy research aimed at breaking through the biochemical bottleneck that makes many middle-aged mammals gain weight.

17 Jun 2004

Leptin News and Research

Further Reading

Research suggests that lack of sleep may be contributing to the obesity pandemic

Battle of Waterloo could help doctors fight death from multiple organ failure

Shp2 protein plays a critical role in obesity

Brain protein called MC4R that plays a role in the urge to eat has now been found to influence appetite in a second way

Hormone leptin could play a key role in treating bone loss, anorexia and infertility in women

Switches in the brain that tell the body to stop eating and start burning calories

Leptin's fat-burning role in humans

U-M scientists say Wnt protein prevents obesity by inhibiting fat cell development

RNA enzyme research may lead to ways of monitoring fat metabolism and might even assist in the search for signs of life on Mars

Nighttime surge of ghrelin may point to new targets for treating obesity

Fat hormone leptin affects a specific type of target neurons in the brain

Stimulation or drugs that target the pro-opiomelanocortin system will be effective in treating diabetes or obesity

Asian Indian men more at risk of type 2 diabetes and cardiovascular disease

Gestational diabetes is a type of diabetes, or high blood sugar, that only pregnant women get

Higher-than-normal amounts of a selenium-containing enzyme could promote type 2 diabetes

Cure for age-induced diabetes or cancer may be nearer than we think

Fat fighting undermined by over active eating pacemaker

Protein in human milk reduces risk of obesity

Sleep apnoea and obesity

New Saint Louis University research sheds light on how obesity occurs

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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