Molecule News and Research

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Concordia researchers link vaping additives to lung damage

The health risks associated with consumption of tobacco and cannabis products are well-established by now. Much less understood are the risks associated with vaping, particularly flavoured products popular with young adults.

4 Apr 2024

Atomic-level structural models of enzymes provide disease insights

When nucleic acids like DNA or RNA build up in a cell's cytoplasm, it sets off an alarm call for the immune system.

2 Apr 2024

miR-205 knockout surprises with enhanced mammary development and cancer insights

New research unveils the paradoxical role of miR-205 in mammary gland development and its potential impact on breast cancer, highlighting the miRNA's complex involvement in stem cell regulation and tumor suppression.

2 Apr 2024

Women's skin study shows distinct chemical changes in response to psychological stress

The volatile organic compounds (VOCs) generated by the skin in response to psychological stress.

29 Mar 2024

Researchers discover a safer and more efficient technique for testing new drugs

McGill researchers have discovered a safer and more efficient technique for testing new drugs while they are in development.

28 Mar 2024

AudioCure Pharma: Novel compound AC102 restores noise-induced hearing loss in preclinical models

A single application of the novel compound AC102 almost completely restores noise-induced hearing loss in preclinical models.

28 Mar 2024

Newly discovered molecule may be a potential therapeutic target for triple-negative breast cancer

A team of researchers from Hiroshima University has discovered a molecule that promotes the production of cancer cells. This molecule may prove to be a potential therapeutic target in the treatment of triple-negative breast cancer, an aggressive form of breast cancer.

27 Mar 2024

Enzymatic cocktail emerges as new hope against mycobacterial infections

With resistance to chemical antibiotics on the rise, the world needs entirely new forms of antibiotics. A new study published in Microbiology Spectrum, a journal of the American Society for Microbiology, shows that an enzymatic cocktail can kill a variety of mycobacterial species of bacteria, including those that cause tuberculosis.

27 Mar 2024

New insights into the exacerbation of psoriasis through specific genetic defects

The inflammatory potential of tissue-resident regulatory T cells in a murine gain of function model.

27 Mar 2024

Ubiquigent and Debiopharm enter agreement to support USP1 inhibitor programme for Debio 0432

Project will be a demonstration of how Ubiquigent’s DUB-centric platform can support the development of DUB inhibitors all the way from discovery through to clinical development.

From Ubiquigent Limited 26 Mar 2024

Researchers identify new potential target for the treatment of Alzheimer's disease

Researchers at the University of Leeds and Lancaster University in the UK have identified a new potential target for the treatment of Alzheimer's disease – PDE4B.

26 Mar 2024

Researchers identify viable vaccine targets for hepatitis C infections

By studying individuals who spontaneously clear hepatitis C infections, a team of researchers has identified viable vaccine targets for a disease that infects 70 million worldwide with case numbers increasing every year.

26 Mar 2024

Researchers develop a novel sensor for the detection of bacteria

Each year, bacterial infections claim several million lives worldwide. That is why detecting harmful microorganisms is crucial – not only in the diagnosis of diseases but also, for example, in food production.

25 Mar 2024

Generative artificial intelligence model can easily design billions of novel antibiotics

Researchers at McMaster University and Stanford University have invented a new generative artificial intelligence model which can design billions of new antibiotic molecules that are inexpensive and easy to build in the laboratory.

22 Mar 2024

Researchers create new platform to identify proteins for targeted treatment of disease

Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins -; a new but largely unrealized approach to the treatment of disease.

22 Mar 2024

Study shows cellular, molecular overlaps in ALS and FTLD

On the surface, the movement disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the cognitive disorder frontotemporal lobar degeneration (FTLD), which underlies frontotemporal dementia, manifest in very different ways. In addition, they are known to primarily affect very different regions of the brain.

22 Mar 2024

Boosting mRNA activity and longevity with multi-tailed structures

Messenger RNA (mRNA) made its big leap into the public limelight during the pandemic, thanks to its cornerstone role in several COVID-19 vaccines

22 Mar 2024

Natural molecule trigonelline can help to improve muscle health and function

A research consortium led by Nestlé Research in Switzerland and the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) made a recent discovery that the natural molecule trigonelline present in coffee, fenugreek, and also in the human body, can help to improve muscle health and function.

22 Mar 2024

Innovative study on asthma inflammation funded by NIH/NIAID grant

In a significant stride for respiratory medicine, Lundquist Institute (TLI) investigator Nicholas Jendzjowsky, PhD, has been awarded a prestigious grant from the National Institute of Health/National Institute of Allergy and Infectious Diseases (NIH/NIAID).

21 Mar 2024

Aging affects regulatory T cells' ability to promote myelin regeneration

Regulatory T lymphocytes are cells that are responsible for regulating the immune system and have regenerative functions in many contexts, including myelin restoration.

20 Mar 2024

Molecule News and Research

Concordia researchers link vaping additives to lung damage

Atomic-level structural models of enzymes provide disease insights

miR-205 knockout surprises with enhanced mammary development and cancer insights

Women's skin study shows distinct chemical changes in response to psychological stress

Researchers discover a safer and more efficient technique for testing new drugs

AudioCure Pharma: Novel compound AC102 restores noise-induced hearing loss in preclinical models

Newly discovered molecule may be a potential therapeutic target for triple-negative breast cancer

Enzymatic cocktail emerges as new hope against mycobacterial infections

New insights into the exacerbation of psoriasis through specific genetic defects

Ubiquigent and Debiopharm enter agreement to support USP1 inhibitor programme for Debio 0432

Researchers identify new potential target for the treatment of Alzheimer's disease

Researchers identify viable vaccine targets for hepatitis C infections

Researchers develop a novel sensor for the detection of bacteria

Generative artificial intelligence model can easily design billions of novel antibiotics

Researchers create new platform to identify proteins for targeted treatment of disease

Study shows cellular, molecular overlaps in ALS and FTLD

Boosting mRNA activity and longevity with multi-tailed structures

Natural molecule trigonelline can help to improve muscle health and function

Innovative study on asthma inflammation funded by NIH/NIAID grant

Aging affects regulatory T cells' ability to promote myelin regeneration

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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