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Researchers identify key molecular alterations from endurance exercise that could combat chronic diseases

A whole-organism molecular map of the temporal effects of endurance training in rats.

3 May 2024

Central and peripheral clock synchronization vital for optimal tissue function

Discovered in the 1970s, circadian clocks are essential for the regulation of biological time in most cells in the human body.

2 May 2024

Protein profiling reveals impact of aging and resistance training on skeletal muscle proteome

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "A novel deep proteomic approach in human skeletal muscle unveils distinct molecular signatures affected by aging and resistance training."

2 May 2024

Premature surgical menopause can lead to increased risk of muscle disorders

Musculoskeletal pain is a prevalent menopause symptom, which helps explain why women typically experience more pain than men, especially around the age of 50 years.

2 May 2024

Study shows synergistic effects of time-restricted eating and high-intensity functional training on health

Combining time-restricted eating with high-intensity functional training may improve body composition and cardiometabolic parameters more than either alone, according to a study published May 1, 2024 in the open-access journal PLOS ONE by Ranya Ameur and Rami Maaloul from the University of Sfax, Tunisia, and colleagues.

2 May 2024

New drug candidate reverses obesity in mice by transforming liver metabolism

A mitochondrial transcription inhibitor (IMT) shifted metabolism in high-fat diet mice toward fatty acid oxidation, leading to weight loss, reduced liver fat, and improved glucose tolerance.

1 May 2024

Menstrual cycle linked to injury risk in female footballers

Football players in England's top-tier WSL were six times more likely to experience a muscle injury in the days leading up to their period compared to when they were on their period, according to new research from UCL, the University of Bath and St. Mary's University.

1 May 2024

Cancer-like cells found in clogged arteries aggravate atherosclerosis

Columbia University researchers have found cells inside clogged arteries share similarities with cancer and aggravate atherosclerosis, raising the possibility that anticancer drugs could be used to treat atherosclerosis and prevent heart attacks.

1 May 2024

Research offers hope to millions of people with complex regional pain syndrome

Complex Regional Pain Syndrome (CRPS) is a chronic and debilitating pain disorder, typically considered lifelong with limited treatment options.

30 Apr 2024

Unlocking the mechanisms of pluripotent cell's fate determination

As embryos, all complex organisms are partially made up of pluripotent stem cells, a term for cells that have the capacity to differentiate into any kind of cell: nerve cells, muscle cells, blood cells, skin cells, and the like.

29 Apr 2024

Japanese researchers test cardiac spheroids for heart regeneration in monkeys

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function.

26 Apr 2024

Low vitamin D tied to belly fat and weak muscles in women

Low vitamin D in women is linked to more belly fat and lower muscle mass. The study suggests using waist-to-height ratio and muscle mass index to assess health risks.

25 Apr 2024

New system personalizes chemotherapy doses for cancer patients

When cancer patients undergo chemotherapy, the dose of most drugs is calculated based on the patient's body surface area. This is estimated by plugging the patient's height and weight into an equation, dating to 1916, that was formulated from data on just nine patients.

24 Apr 2024

Timelapse breakthrough: Scientists capture secrets of early embryonic cell division

The beginning of life is shrouded in mystery. While the intricate dynamics of mitosis is well-studied in the so-called somatic cells – the cells that have a specialized function, like skin and muscle cells – they remain elusive in the first cells of our bodies, the embryonic cells.

24 Apr 2024

Study unveils novel bladder cancer diagnostic model based on key mitochondrial genes

A novel diagnostic model using machine learning (ML).

24 Apr 2024

FDA approval of Anktiva heralds a new era in the treatment of BCG-unresponsive non–muscle-invasive bladder cancer

The U.S. Food and Drug Administration (FDA) has approved the immunotherapy-boosting drug N-803, which is marketed under the brand name Anktiva, to be used in combination with the immunotherapy Bacillus Calmette-Guerin (BCG) for the treatment of patients with BCG-unresponsive non–muscle-invasive bladder cancer.

23 Apr 2024

Unlocking the potential of insects as sustainable protein sources

Could insects be a viable alternative source of protein in our diets? Researchers from the University of Surrey need your help to get to the bottom of this much-debated question.

23 Apr 2024

New models improve heart disease risk prediction, especially for women

When it comes to matters of the heart, cardiovascular disease in women is underdiagnosed compared to men. A popular scoring system used to estimate how likely a person is to develop a cardiovascular disease within the next 10 years is the Framingham Risk Score. It is based on factors including age, sex, cholesterol levels, and blood pressure.

23 Apr 2024

Aster DM Healthcare reveals top foods to combat PCOS symptoms

Google searches related to Polycystic Ovary Syndrome (PCOS) reached an all-time high in April 2024 globally, indicating a growing concern and interest in understanding and managing this condition.

23 Apr 2024

Does diabetes increase the risk of long COVID?

A recent study in eClinicalMedicine assesses whether individuals with diabetes are more susceptible to developing long COVID, analyzing a UK cohort to explore the prolonged impact of SARS-CoV-2 infection in this population.

22 Apr 2024