Neurodegenerative Disease News and Research

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Investigational gene therapy shows promise for rare childhood neurodegenerative disease

An investigational gene therapy for a rare neurodegenerative disease that begins in early childhood, known as giant axonal neuropathy (GAN), was well tolerated and showed signs of therapeutic benefit in a clinical trial led by the National Institutes of Health.

20 Mar 2024

Skin biopsy test shows promise in diagnosing Parkinson's disease and synucleinopathies

In a paper published in the Journal of the American Medical Association (JAMA), neurologists at Beth Israel Deaconess Medical Center (BIDMC) showed that a simple skin biopsy test detects an abnormal form of alpha-synuclein, the pathological hallmark of Parkinson's disease and the subgroup of neurodegenerative disorders known as synucleinopathies, at high positivity rates.

20 Mar 2024

New compounds show potential to mimic benefits of exercise

Doctors have long prescribed exercise to improve and protect health. In the future, a pill may offer some of the same benefits as exercise.

18 Mar 2024

Microfluidic chips advance neurodegenerative disease research

Researchers review the role of microfluidic chip models in understanding neurodegenerative diseases, offering insights into the disease mechanisms and potential for drug development through innovative lab-on-a-chip technologies.

14 Mar 2024

Study links magnetite particle exposure to Alzheimer's disease symptoms

Magnetite, a tiny particle found in air pollution, can induce signs and symptoms of Alzheimer's disease, new research suggests.

29 Feb 2024

Novel brain organoid model unveils link between inflammation and astrocyte dysfunction

The brain is typically depicted as a complex web of neurons sending and receiving messages. But neurons only make up half of the human brain.

28 Feb 2024

Study reveals pivotal insights into the progression of Parkinson's disease

Parkinson's disease, the second most common type of progressive dementia after Alzheimer's disease, affects nearly 1 million people in the U.S. and an estimated 10 million individuals worldwide.

24 Feb 2024

Aptamer and Neuro-Bio enter the second phase of Alzheimer’s test development

Aptamer Group plc, the developer of novel Optimer binders to enable innovation in the life sciences industry, announces the second phase of its on-going partnership with Neuro-Bio, an Oxfordshire-based biotechnology company with a therapeutic focus on neurodegenerative disease, to develop Optimer binders for a lateral flow test for the early diagnosis of Alzheimer’s disease

From Aptamer Group 22 Feb 2024

Chan Zuckerberg Initiative funds Notre Dame research on aging and neurodegeneration

The University of Notre Dame has received a Collaborative Pairs Pilot Project Award from the Chan Zuckerberg Initiative to study genes that affect neurodegenerative diseases, such as Alzheimer's disease.

21 Feb 2024

Scientists identify new therapeutic approach for combating neurodegenerative diseases

A team led by scientists at the Case Western Reserve University School of Medicine has identified a new therapeutic approach for combating neurodegenerative diseases, offering hope of improved treatments for Alzheimer's disease, Parkinson's disease, Vanishing White Matter disease and multiple sclerosis, among others.

20 Feb 2024

Researchers introduce a pioneering approach to combat neurodegenerative diseases

Researchers led by Northwestern University and the University of Wisconsin-Madison have introduced a pioneering approach aimed at combating neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and Amyotrophic lateral sclerosis (ALS).

16 Feb 2024

Study links Agent Orange exposure to neurodegenerative diseases

Agent Orange, an herbicide used during the Vietnam War, is a known toxin with wide-ranging health effects.

14 Feb 2024

Cytokine interferon-gamma can be a disease-modifying therapeutic target in multiple system atrophy

Multiple system atrophy is a rare and fatal neurodegenerative disease, where insoluble inclusions of the protein alpha-synuclein appear in oligodendrocyte cells of the brain.

12 Feb 2024

Olive oil's secret weapon against Alzheimer's: phenolic compounds

A comprehensive review in the International Journal of Molecular Sciences highlights the potential of extra-virgin olive oil and its phenolic compounds in preventing and treating Alzheimer's disease through various mechanisms, including reducing amyloid-beta accumulation and neuroinflammation.

12 Feb 2024

Study reveals role of protein modification in neurodegenerative disease progression

Neurodegenerative diseases, such as Alzheimer's and Parkinson's, present a significant health challenge, affecting over 50 million people globally.

12 Feb 2024

Unlocking Alzheimer's secrets: Study pinpoints APOE4's harmful effect on lipids

UNC School of Medicine researcher Sarah Cohen, PhD, and Ian Windham, a former PhD student from the Cohen lab, have made a new discovery about apolipoprotein E (APOE) – the biggest genetic risk factor for late-onset Alzheimer's disease.

9 Feb 2024

Rucaparib and its major metabolite exhibit differential biological activity and synergy

Once they enter the body, drugs, apart from carrying out their therapeutic function, are biochemically transformed by the action of the metabolic machinery, a process that facilitates their expulsion.

9 Feb 2024

Interdisciplinary dream team receives $3 million grant to revolutionize Alzheimer's diagnosis

What do a synthetic chemist, a medical imaging expert, and a neurologist have in common? They're coming together in the Biomedical Imaging Center at the Beckman Institute for Advanced Science and Technology to develop better diagnostic tools and imaging agents to detect early-stage Alzheimer's disease and other neurodegenerative diseases.

6 Feb 2024

Bioprinting breakthrough: Tech platform creates 3D neural tissues in which neurons and glia connect

Researchers produced 3D bioprinted human brain tissues, allowing for the creation of functioning neural networks that could simulate network activity in normal and pathological situations.

6 Feb 2024

Gut health linked to Alzheimer's progression, study suggests diet as potential therapy

Study reviews the intricate relationship between diet, gut microbiome diversity, and Alzheimer’s disease progression, suggesting gut health could play a key role in managing the disease.

3 Feb 2024

Neurodegenerative Disease News and Research

Investigational gene therapy shows promise for rare childhood neurodegenerative disease

Skin biopsy test shows promise in diagnosing Parkinson's disease and synucleinopathies

New compounds show potential to mimic benefits of exercise

Microfluidic chips advance neurodegenerative disease research

Study links magnetite particle exposure to Alzheimer's disease symptoms

Novel brain organoid model unveils link between inflammation and astrocyte dysfunction

Study reveals pivotal insights into the progression of Parkinson's disease

Aptamer and Neuro-Bio enter the second phase of Alzheimer’s test development

Chan Zuckerberg Initiative funds Notre Dame research on aging and neurodegeneration

Scientists identify new therapeutic approach for combating neurodegenerative diseases

Researchers introduce a pioneering approach to combat neurodegenerative diseases

Study links Agent Orange exposure to neurodegenerative diseases

Cytokine interferon-gamma can be a disease-modifying therapeutic target in multiple system atrophy

Olive oil's secret weapon against Alzheimer's: phenolic compounds

Study reveals role of protein modification in neurodegenerative disease progression

Unlocking Alzheimer's secrets: Study pinpoints APOE4's harmful effect on lipids

Rucaparib and its major metabolite exhibit differential biological activity and synergy

Interdisciplinary dream team receives $3 million grant to revolutionize Alzheimer's diagnosis

Bioprinting breakthrough: Tech platform creates 3D neural tissues in which neurons and glia connect

Gut health linked to Alzheimer's progression, study suggests diet as potential therapy

Aneuro: A Year of Neuroscience in Review eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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