Pathogen News and Research

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$1.6 million ecological stoichiometry grant to study how certain nutrients affect the development of disease in humans and animals

Two University of Kansas and four Arizona State University researchers have received an almost $1.6 million grant from the National Science Foundation to study how certain nutrients affect the development of disease in humans and animals.

29 Jun 2004

Research for faster Polymerase Chain Reaction technology

Imagine being able to diagnose a viral strain at the site of an outbreak or identifying a deadly pathogen on the battlefield.

28 Jun 2004

Molecular biologists find chink in the armor of Candida, the most common human fungal pathogen

Molecular biologists at Rice University have discovered a key defense mechanism that the yeast Candida albicans uses against attack by the human immune system.

26 Jun 2004

Discovery could pave the way to smallpox Immunity

A team of scientists led by a Howard Hughes Medical Institute (HHMI) international research scholar has discovered the immune system mechanism that causes some mice to be more susceptible to mousepox than others.

9 Jun 2004

Link between oral bacterium and premature babies

For years, scientists have noticed a particular oral bacterium can be found in the amniotic fluid of about 20 percent of women with premature babies.

27 May 2004

Research into flipping genes therapy by Leeds University

Graham Cook and Erica de Wynter of molecular medicine have secured £125,000 to investigate the unique way antibody genes are assembled and how they can be harnessed to fight disease.

25 May 2004

Researchers to develop a highly sensitive, portable method of detecting bioterror agents like anthrax

Their method uses "Cellular Analysis and Notification of Antigen Risks and Yields" (CANARY) cells, which are immune-system cells engineered to contain a fluorescent protein naturally found in jellyfish. CANARY cells have the immune system's ability to detect specific disease-causing agents, lighting up when they recognize a pathogen.

24 May 2004

KETEK® (telithromycin) is highly active in vitro against Streptococcus pneumoniae (S. pneumoniae) isolates

Results from an ongoing surveillance study, PROTEKT US (Prospective Resistant Organism Tracking and Epidemiology of the Ketolide Telithromycin – United States) Year 2 (2001-2002), suggest that KETEK® (telithromycin) is highly active in vitro against Streptococcus pneumoniae (S. pneumoniae) isolates, including those resistant to other antimicrobial agents.

24 May 2004

To sleep…

Proteomic analysis using mass spectrometry could be used in a diagnostic test for sleeping sickness that can more accurately spot the disease than current approaches.

18 May 2004

Researchers demonstrate wearable electronics to aid health and fashion

Soon you may be wearing your computer, or elements of it, according to a team of researchers and designers at Arizona State University. The era of smart bodysuits is about to begin.

17 May 2004

International research team have decoded the genetic blueprint of the tularemia (rabbit fever) bacterium

Two teams of researchers, one based in the United States and the other in Europe, have decoded the genetic blueprint of the tularemia (rabbit fever) bacterium, a highly infectious human and animal pathogen.

6 May 2004

Protein in the male reproductive tract is a potent anti-bacterial agent

Scientists at the University of North Carolina at Chapel Hill have found that a protein they discovered three years ago in the male reproductive tract is a potent anti-bacterial agent.

6 May 2004

Time matters when treating fungal infections in newborns

A new UCLA study shows that ‘time matters’ when treating fungal infections in neonates and that earlier treatment can mean the difference between life and death.

1 May 2004

New technique of identifying genes may help researchers developing drugs

A quick new technique able to identify genes that evolve rapidly as well as those that change slowly already has pinpointed new targets for researchers developing drugs against tuberculosis and malaria, and it could do the same for other infectious diseases, according to a paper in this week's Nature.

29 Apr 2004

New device filters blood supplies on-site reducing the possible transmission of Creutzfeldt-Jakob disease

ProMetic Life Sciences Inc. has announced today that its joint venture with the American Red Cross, Pathogen Removal and Diagnostic Technology Inc. ("PRDT"), has confirmed that treatment of TSE spiked red blood cell concentrate with its Prion Reduction Device results in a significant decrease in associated infectivity.

5 Apr 2004

Researchers tap modified plant viruses to ward off cervical cancer-causing infections

New vaccinations to prevent infections that lead to cervical cancer and targeted therapeutics aimed at breast cancer were examples of research highlights presented by scientists today at the 95th Annual Meeting of the American Association for Cancer Research. Scientists described advances that feed into the drug development 'pipeline,' and show strong promise for controlling existing tumors or addressing the pathogen that causes tumors.

29 Mar 2004

Comparative genomics to cast new light on other spirochete microbes

Three centuries after a pioneering Dutch microbiologist first observed the spiral-shaped oral pathogen Treponema denticola, scientists have deciphered the bacterium’s entire DNA sequence and used comparative genomics to cast new light on other spirochete microbes.

29 Mar 2004

Cryptosporidium parvum parasite could help to develope new therapies for the disease

Cryptosporidium parvum, an insidious, one-celled, waterborne parasite that lodges in the intestines of infected people and animals and for which there is currently no effective treatment, is missing key structures normally found in similar parasites, say researchers supported by the National Institute of Allergy and Infectious Diseases (NIAID), one of the National Institutes of Health. The results of their genome sequencing project, could help scientists home in on new drug targets that may lead to therapies for the disease.

26 Mar 2004

£5m for HIV/AIDS trial involving HIV patients in London, Moscow, South Africa and Australia

A joint Oxford University/Imperial College research programme into HIV/AIDS has received £5 million support from the Wellcome Trust to carry out a drug trial involving HIV patients in London, Moscow, South Africa and Australia.

24 Mar 2004

Scientists identify genetic changes during infection by tuberculosis

Researchers at the Center for Biomedical Inventions at UT Southwestern Medical Center at Dallas have identified the genetic changes that Mycobacterium tuberculosis, the bacterium that causes tuberculosis, undergoes during infection of a living host.

22 Mar 2004