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SSRI antidepressants may be unsuitable for children

A UK study in this week's issue of THE LANCET suggests that reliance on published studies alone to guide the treatment of childhood depression could be inappropriate. A systematic review including published and unpublished data shows that only one drug, fluoxetine (Prozac), was not associated with negative outcomes for children with depression.

22 Apr 2004

Breast cancer reduction findings need further investigation

Last month, an observational study conducted by the Women’s Health Initiative (WHI) was halted prematurely because of possible risks associated with the use of conjugated equine estrogen (CEE) therapy in women who have undergone hysterectomy.

22 Apr 2004

FDA Approves PROSCAR® Combined With Doxazosin to Reduce the Risk of Benign Prostatic Hyperplasia Symptoms

Merck & Co., Inc. today announced that the Food and Drug Administration (FDA) has approved changes to the prescribing information for PROSCAR® (finasteride) based on a landmark National Institutes of Health (NIH) study.

20 Apr 2004

Dietary supplement may improve immune function in the elderly

A recent clinical study has demonstrated that 7-oxo Dehydroepiandrosterone taken orally twice daily by healthy adults over a period of one month augments several key T-cell mediated immune function parameters compared to placebo administration.

20 Apr 2004

Iron may significantly improve women's attention, short-term and long-term memory

Young women who took iron supplementation for 16 weeks significantly improved their attention, short-term and long-term memory, and their performance on cognitive tasks, even though many were not considered to be anemic when the study began, according to researchers at Pennsylvania State University.

19 Apr 2004

Chinese mushrooms can improve physical well-being

Nutritionists have since joined with manufacturers to produce supplements using fermentation from this rare mushroom. One such product is CordyMax®, made with a formula recognized in China as the fermented Cordyceps mushroom mycelial product. CordyMax® has been placed under intellectual property protection, and only one company has the license for it outside of China.

19 Apr 2004

Liptor helps Alzheimer’s disease

In a small clinical trial enrolling 63 individuals with Alzheimer’s disease, half of those who received atorvastatin (Lipitor) stabilized or improved after one year of treatment, the trial’s principal investigator D. Larry Sparks, Ph.D., reported today at a professional meeting on Alzheimer therapy.

15 Apr 2004

Women get better picture on hormone replacement therapy

Detailed results of the "estrogen-alone" study within the Women's Health Initiative (WHI), which was terminated in early March 2004, are providing some of the first answers to questions about the efficacy of estrogen alone to prevent chronic disease in healthy, postmenopausal women who have had a hysterectomy.

14 Apr 2004

Ultrasound therapy does nothing to help an injured skeletal muscle heal any faster

Although ultrasound is one of the most frequently prescribed treatments for one of the most common sport and athletic injuries – skeletal muscle contusions – there's really no good scientific evidence showing that it treats injured muscles effectively, said Steven Devor, the study's lead author and an assistant professor of sport and exercise sciences at Ohio State University.

14 Apr 2004

Estrogen-alone hormone therapy had no effect on coronary heart disease risk

A large, multi-center heart disease prevention study, part of the Women's Health Initiative (WHI), found that estrogen-alone hormone therapy had no effect on coronary heart disease risk but increased the risk of stroke for postmenopausal women.

13 Apr 2004

Drug's ability to reverse acute ischemic stroke

Ischemic stroke patients who arrive at the hospital too late to receive currently available treatment options might someday have a new treatment option. Northwestern Memorial Hospital is the only site in Chicago to participate in a phase III trial of abciximab (ReoPro - Centocor/Eli Lilly and Company), which seeks to determine the drug's ability to improve neurological function and minimize disability in patients who present with an acute ischemic stroke.

13 Apr 2004

Vitamin C can reduce levels of C-reactive protein, a marker of inflammation and chronic disease

Vitamin C supplements can reduce levels of C-reactive protein, a marker of inflammation and chronic disease risk in humans, according to a new study led by researchers at the University of California, Berkeley.

12 Apr 2004

Study suggests ways to prevent prostate cancer

Current information on prostate cancer risk factors suggests that some cases might be prevented. One possible risk factor that can be changed is diet. You may be able to reduce your risk of prostate cancer by changing the way you eat.

11 Apr 2004

A drug that improves function of retinal blood vessels may be able to reduce the risk of stroke

The small study found that endothelial function is abnormal in eye blood vessels of patients who have early-stage hypertension, but that treatment with an angiotensin-receptor blocker (ARB) drug improves endothelial function. The endothelium is the lining of vessel walls and plays a key role in the vessels’ ability to relax and to constrict.

9 Apr 2004

Cinacalet helps control overactive thyroids, a major complication of advanced kidney disease

A new drug can help control an overactive thyroid, a major complication of advanced kidney disease, by playing a trick on the gland, a new study finds. The drug, cinacalet, is much more effective at keeping the parathyroid gland working normally than a placebo, according to the study. It may be a good alternative to standard therapy, researchers said.

7 Apr 2004

Celadrin arthritis topical cream significantly reduces pain

Celadrin is a novel compound developed through a proprietary process. The product is an all-natural ingredient which has been clinically shown to provide joint health, flexibility and improved quality of life on a cumulative basis with no reported side effects.

7 Apr 2004

Oral sildenafil improved exercise tolerance, cardiac output and quality of life in 22 patients with primary pulmonary hypertension

Oral sildenafil (Viagra®) improved exercise tolerance, cardiac output and quality of life in 22 patients with primary pulmonary hypertension, according to the results of the first randomized, placebo-controlled, double-blind, crossover study, reported in the April 7, 2004 issue of the Journal of the American College of Cardiology.

6 Apr 2004

FDA accepts REMICADE® (infliximab) for the treatment of early rheumatoid arthritis

Centocor, Inc., announced today that the U.S. Food and Drug Administration (FDA) has accepted its filing of a supplemental Biologics License Application (sBLA) for REMICADE® (infliximab) as first-line therapy, in combination with methotrexate, for the treatment of early rheumatoid arthritis (RA) patients with moderately-to-severely active disease. REMICADE®, in combination with methotrexate, is currently indicated in the U.S. for reducing signs and symptoms, inhibiting the progression of structural damage and improving physical function in patients with moderately-to-severely active RA who have had an inadequate response to methotrexate alone.

6 Apr 2004

Phase 3 study of drug teduglutide in patients with short bowel syndrome

Teduglutide is an analog of glucagon-like peptide 2 (GLP-2), a naturally occurring hormone that regulates the growth, proliferation and maintenance of cells lining the gastrointestinal tract. Teduglutide has been shown in animal studies and previous human clinical trials to increase the size and number of these cells, thereby increasing the absorptive surface area of the intestines.

6 Apr 2004

Placebo News and Research

SSRI antidepressants may be unsuitable for children

Breast cancer reduction findings need further investigation

FDA Approves PROSCAR® Combined With Doxazosin to Reduce the Risk of Benign Prostatic Hyperplasia Symptoms

Dietary supplement may improve immune function in the elderly

Iron may significantly improve women's attention, short-term and long-term memory

Chinese mushrooms can improve physical well-being

Liptor helps Alzheimer’s disease

Women get better picture on hormone replacement therapy

Ultrasound therapy does nothing to help an injured skeletal muscle heal any faster

Estrogen-alone hormone therapy had no effect on coronary heart disease risk

Drug's ability to reverse acute ischemic stroke

Vitamin C can reduce levels of C-reactive protein, a marker of inflammation and chronic disease

Study suggests ways to prevent prostate cancer

A drug that improves function of retinal blood vessels may be able to reduce the risk of stroke

Cinacalet helps control overactive thyroids, a major complication of advanced kidney disease

Celadrin arthritis topical cream significantly reduces pain

Oral sildenafil improved exercise tolerance, cardiac output and quality of life in 22 patients with primary pulmonary hypertension

FDA accepts REMICADE® (infliximab) for the treatment of early rheumatoid arthritis

Phase 3 study of drug teduglutide in patients with short bowel syndrome

More evidence needed to link symptoms like tics or behavioral problems to a strep infection

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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