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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Study explores the effects of ovulation inducing method on embryo quality

Low birth rates have become a serious problem in many developed countries throughout the world, with Japan being a prime example. In Japan particularly, aging and stress have led to a massive rise in infertility, which now affects one in every 4.4 couples.

22 Apr 2024

Protecting telomeres: ILF3 and the regulation of R-loop dynamics

Dysregulated R-loops can cause stalled replication forks and telomere instability. However, how R-loops are recognized and regulated, is still not well understood, particularly at telomeres.

22 Apr 2024

Study reveals key protein's role in balancing immune response to viral infections

Researchers have revealed the regulatory mechanism of a specific protein that plays a key role in balancing the immune response triggered by viral infections in mammal cells.

18 Apr 2024

New urine-based test improves identification of high-grade prostate cancer

Researchers at the University of Michigan Rogel Cancer Center have developed a new urine-based test that addresses a major problem in prostate cancer: how to separate the slow-growing form of the disease unlikely to cause harm from more aggressive cancer that needs immediate treatment.

18 Apr 2024

First-of-its-kind AI tool predicts patient response to cancer drugs at single-cell resolution

With more than 200 types of cancer and every cancer individually unique, ongoing efforts to develop precision oncology treatments remain daunting.

18 Apr 2024

Discovery of new vascular cell type may pave way for novel strategies to treat cardiovascular diseases

Cardiovascular diseases, including stroke and myocardial infarction, are the world's leading causes of mortality, accounting for over 18 million deaths a year.

18 Apr 2024

New trials show promise for immune checkpoint blockers in early-stage lung cancer

A dendritic cell (DC) vaccine targeting patient-specific neoantigens to patients with resected non-small cell lung cancer (NSCLC).

18 Apr 2024

Tracking arboviruses by nanopore sequencing of mosquitoes

The technology used to sequence SARS-CoV-2 at record speed early in the COVID-19 pandemic has been successfully tested as a technique to monitor arboviruses and diseases transmitted mainly by mosquitoes.

17 Apr 2024

Study findings better define the genetic landscape of neuroendocrine tumors of the cervix

In an ambitious new study, a research team that included scientists from Yale set out to uncover potential treatments for patients with rare neuroendocrine tumors of the cervix (NETc) by understanding the molecular basis of the aggressive disease.

17 Apr 2024

Study highlights how age affects nasal cell response to SARS-CoV-2

Researchers reveal age-related differences in nasal epithelial cell responses to SARS-CoV-2, showing variations in cell types and viral dynamics across pediatric, adult, and older adult groups.

16 Apr 2024

Common HIV drugs linked to reduced Alzheimer's disease risk

Alzheimer's disease (AD) currently afflicts nearly seven million people in the U.S. With this number expected to grow to nearly 13 million by 2050, the lack of meaningful therapies represents a major unmet medical need.

16 Apr 2024

MD Anderson and CureVac collaborate on mRNA-based cancer vaccines

The University of Texas MD Anderson Cancer Center and CureVac N.V. today announced a co-development and licensing agreement to develop novel mRNA-based cancer vaccines.

16 Apr 2024

Placental IGFBP1: A key factor in development of gestational diabetes

A new study led by the Harvard Pilgrim Health Care Institute has identified that a deficit in the placental expression of the gene insulin-like growth factor 1 (IGFBP1) and low IGFBP1 circulating levels are associated with insulin resistance during pregnancy, highlighting a potential risk factor for the development of gestational diabetes.

16 Apr 2024

Pitt researchers uncover mechanisms behind uveal melanoma resistance

New research from the University of Pittsburgh explains why metastatic uveal melanoma is resistant to conventional immunotherapies and how adoptive therapy, which involves growing a patient's T cells outside the body before reinfusing them, can successfully treat this rare and aggressive cancer.

16 Apr 2024

Novel vaccine approach effective against all virus strains

Scientists at UC Riverside have demonstrated a new, RNA-based vaccine strategy that is effective against any strain of a virus and can be used safely even by babies or the immunocompromised.

15 Apr 2024

Texas A&M scientists elucidate how phages disarm antibiotic-resistant bacteria

Bacterial infections pose significant challenges to agriculture and medicine, especially as cases of antibiotic-resistant bacteria continue to rise.

15 Apr 2024

Study reveals age-specific differences in nasal cells' response to SARS-CoV-2

Important differences in how the nasal cells of young and elderly people respond to the SARS-CoV-2 virus, could explain why children typically experience milder COVID-19 symptoms, finds a new study led by researchers at UCL and the Wellcome Sanger Institute.

15 Apr 2024