Transcriptomics News and Research

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Researchers map early genetic development of the brain

In an article published in Nature, researchers from Karolinska Institutet present an atlas of the early development of the brain.

3 May 2024

Researchers identify key molecular alterations from endurance exercise that could combat chronic diseases

A whole-organism molecular map of the temporal effects of endurance training in rats.

3 May 2024

Study uncovers molecular mechanism linking nonsense-mediated RNA decay to microcephaly

Nonsense-mediated RNA decay, or NMD, is an evolutionarily conserved molecular mechanism in which potentially defective messenger RNAs, or mRNAs (genetic material that instructs the body on how to make proteins), are degraded.

1 May 2024

New study reveals potential cellular mechanism behind cognitive decline in Alzheimer's

Researchers have developed a robust method for identifying rare brain neurons that re-enter the cell cycle, offering insights into their role in cognitive disorders such as Alzheimer's disease.

28 Apr 2024

Multi-omics approach powers Karolinska Institutet's Single Cell Atlas

Researchers at Karolinska Institutet have developed a web-based platform that offers an unprecedented view of the human body at the cellular level.

25 Apr 2024

Study unveils novel bladder cancer diagnostic model based on key mitochondrial genes

A novel diagnostic model using machine learning (ML).

24 Apr 2024

Spatiotemporal transcriptomics reveals insights into primate ovarian aging

The ovary is an essential organ for female fertility, and its age-dependent decline in function is a major cause of infertility.

18 Apr 2024

First-of-its-kind AI tool predicts patient response to cancer drugs at single-cell resolution

With more than 200 types of cancer and every cancer individually unique, ongoing efforts to develop precision oncology treatments remain daunting.

18 Apr 2024

Machine learning reveals age-related decline in stemness across human tissues

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 7, entitled, "Evidence of a pan-tissue decline in stemness during human aging."

16 Apr 2024

Study reveals molecular changes in brain cells with Lewy bodies

A new study from Van Andel Institute scientists offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson's disease and some dementias.

16 Apr 2024

Tumor microbiomes offer new insights for enhancing cancer therapies

Comprehensive review reveals the significant impact of tumor-resident bacteria on metastatic cancer, showing how microbiome genomes influence tumor biology, immune system response, and treatment effectiveness. It lays the groundwork for utilizing bacteria-focused therapies to complement traditional cancer treatments.

11 Apr 2024

New ovarian atlas paves the way for extended fertility and hormone restoration

A new "atlas" of the human ovary provides insights that could lead to treatments restoring ovarian hormone production and the ability to have biologically related children, according to University of Michigan engineers.

5 Apr 2024

Scientists identify distinct molecular signatures for sepsis diagnosis and prognosis

Researchers from Lund University in Sweden have identified distinct molecular signatures associated with the clinical signs of sepsis that could provide more accurate diagnosis and prognosis of sepsis, as well as help to target specific therapies at patients who would benefit most, according to new research being presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024) in Barcelona, Spain (27-30 April).

30 Mar 2024

Digital twins: Revolutionizing autoimmune disease treatment

Individual patients with autoimmune diseases can receive tailored medication by computationally treating their so-called digital twins with thousands of medications.

20 Mar 2024

NUS study reveals key mechanisms behind drug resistance in relapsed acute myeloid leukemia

Scientists from the National University of Singapore (NUS) have discovered that the evasion of apoptosis is a key driver of drug resistance in patients with relapsed acute myeloid leukaemia (AML), a type of aggressive blood cancer.

19 Mar 2024

Researchers discover diverse and spatially coordinated cardiac cells involved in heart development

Researchers use a combination of scRNA-seq and multiplexed error-robust fluorescence in situ hybridization to better understand cardiac cell types.

13 Mar 2024

Breakthrough nanopipette enables real-time observation of cancer cell reactions to treatment

The high-tech double-barrel nanopipette, developed by University of Leeds scientists, and applied to the global medical challenge of cancer, has - for the first time - enabled researchers to see how individual living cancer cells react to treatment and change over time – providing vital understanding that could help doctors develop more effective cancer medication.

6 Mar 2024

Transcriptomics News and Research

Researchers map early genetic development of the brain

Researchers identify key molecular alterations from endurance exercise that could combat chronic diseases

Study uncovers molecular mechanism linking nonsense-mediated RNA decay to microcephaly

New study reveals potential cellular mechanism behind cognitive decline in Alzheimer's

Multi-omics approach powers Karolinska Institutet's Single Cell Atlas

Study unveils novel bladder cancer diagnostic model based on key mitochondrial genes

Spatiotemporal transcriptomics reveals insights into primate ovarian aging

First-of-its-kind AI tool predicts patient response to cancer drugs at single-cell resolution

Machine learning reveals age-related decline in stemness across human tissues

Study reveals molecular changes in brain cells with Lewy bodies

Tumor microbiomes offer new insights for enhancing cancer therapies

New ovarian atlas paves the way for extended fertility and hormone restoration

Scientists identify distinct molecular signatures for sepsis diagnosis and prognosis

Digital twins: Revolutionizing autoimmune disease treatment

NUS study reveals key mechanisms behind drug resistance in relapsed acute myeloid leukemia

Researchers discover diverse and spatially coordinated cardiac cells involved in heart development

Breakthrough nanopipette enables real-time observation of cancer cell reactions to treatment

Harvard's Catherine Brownstein's Multi-Omics Approach: A New Horizon for Understanding Rare Pediatric Disorders

AI and predictive medicine: Recent advances

COVID-19's neurological effects linked to immune response, not direct viral attack

Omics eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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