UK Biobank News and Research

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Link between long-term hyperglycemia and upper-limb musculoskeletal conditions revealed

Study demonstrates that long-term hyperglycemia significantly increases the risk of upper-limb musculoskeletal conditions, while BMI influences the risk of carpal tunnel syndrome and Dupuytren's disease differently.

23 Jan 2024

Metabolic syndrome linked to higher osteoarthritis risk, UK Biobank study finds

The association between metabolic syndrome (MetS) and the risk of osteoarthritis (OA).

23 Jan 2024

NHS Health Check linked to lower disease rates and mortality, study shows

Attending an NHS Health Check appointment -; a preventative screening programme offered for free in the UK -; is associated with both a decreased risk of dying and a decreased risk of several diseases, including dementia and liver cirrhosis.

22 Jan 2024

Migraine linked to increased risk of inflammatory bowel disease in new study

A nationwide cohort study reveals that individuals with migraine have a 1.3-fold higher risk of developing inflammatory bowel disease (IBD), suggesting a significant connection between migraine and IBD.

15 Jan 2024

Pioneering Genomic Progress: An Interview with Rami Mehio, Illumina's Software and Informatics Expert

In this interview, Rami Mehio, head of software and informatics at Illumina, shares his experiences and contributions to major genomic projects like the UK Biobank's whole genome sequencing. He discusses the challenges and innovations in genomic data analysis, highlighting Illumina's role in advancing genetic research and precision medicine.

From Illumina, Inc. 15 Jan 2024

Ancient DNA traces multiple sclerosis origins to 5,000-year-old migrations

Researchers create the world's largest ancient human gene bank, linking genes to multiple sclerosis risk and tracing its origins to migrations 5,000 years ago.

13 Jan 2024

Groundbreaking study uncovers hundreds of genetic markers linked to insulin resistance

A genome-wide study of 402,398 individuals identifies 369 SNPs associated with insulin resistance, offering insights into metabolic diseases and potential therapeutic targets.

11 Jan 2024

Landmark study confirms five key Parkinson's Disease variants in largest meta-analysis

Rare Parkinson’s disease (PD) variants in a large-scale cohort.

10 Jan 2024

Study identifies hormonal and reproductive factors for rheumatoid arthritis in women

Early menopause-;before the age of 45-;taking hormone replacement therapy (HRT), and having 4 or more children are among several hormonal and reproductive factors linked to a heightened risk of rheumatoid arthritis in women, finds a large long term study published in the open access journal RMD Open.

9 Jan 2024

Causal effects of lipids, lipoproteins, and other metabolites on blood pressure

The causal effects of lipoprotein particles, lipids, and other metabolites on blood pressure (BP).

9 Jan 2024

Researchers harness the power of AI to enhance assessment of the heart's right ventricle

In a milestone study, researchers from the Icahn School of Medicine at Mount Sinai have harnessed the power of artificial intelligence (AI) to enhance the assessment of the heart's right ventricle, which sends blood to the lungs.

4 Jan 2024

Large-scale study uncovers modifiable risk factors for young-onset dementia

Researchers have identified a wide range of risk factors for young-onset dementia.

26 Dec 2023

Unlocking personalized treatment for millions with high blood pressure

HMRI and University of Newcastle researcher, Professor Murray Cairns, along with his Precision Medicine team have discovered a way of predicting who will respond to blood pressure treatments to lower sodium in the body.

26 Dec 2023

Air pollution linked to increased risk of stroke and dementia transition, study reveals

Study finds that long-term exposure to air pollution increases the risk of transitioning from stroke to dementia, emphasizing the need for stricter air quality controls.

17 Dec 2023

Study points to binge drinking and genetics as key factors in liver disease

Those who binge drink and have a certain genetic makeup are six times more likely to develop alcohol-related cirrhosis, according to new research from UCL, the Royal Free Hospital, the University of Oxford and the University of Cambridge.

14 Dec 2023

Association of genetically proxied PDE5 inhibition with measures of fertility, sexual behavior, and wellbeing

Researchers performed a two-sample Mendelian randomization analysis to investigate the associations between genetically proxied suppression of PDE5, a recognized pharmacological target for erectile dysfunction, fertility, subjective wellness, and sexual behavior.

14 Dec 2023

UK Biobank data shows dose-dependent link between smoking and brain shrinkage

Smoking shrinks the brain, according to a study by researchers at Washington University School of Medicine in St. Louis.

12 Dec 2023

Healthy plant-based diet associated with lower risk of type 2 diabetes

At least 75 per cent of type 2 diabetes cases could be avoided by adopting a healthy lifestyle. A plant-based diet has been shown to play a key role in this.

11 Dec 2023

New map offers valuable insights into the underlying mechanisms of neurodevelopmental disorders and cancer

Scientists have created the first extensive map showing how all possible genetic changes can affect health in the gene DDX3X, leading to valuable insights into the underlying mechanisms of neurodevelopmental disorders and cancer.