High throughput (HT) gene to antibody platform-TurboCHO

High throughput (HT) gene-to-antibody manufacturing is the most economical choice for small-scale recombinant antibodies. Small-scale projects can be finished in as little as 10 business days with the help of GenScript’s high throughput gene synthesis platform and unique TurboCHO™ transient expression technology.

Small-scale projects begin with customer-supplied sequences and end with purified products.

A vast capacity of 10,000+ targets/month makes it possible to hasten medicines' development and global commercialization. Various purified antibody products, including IgGs, Fab, scFv, VHH, bi-specific antibodies, and more, can be delivered in large quantities (i.e., from ug to mg) using the TurboCHO™ High Throughput platform.

The automated technology assisting the TurboCHO™ High Throughput platform eliminates lot-to-lot variation and guarantees a high expression level.

High throughput (HT) gene to antibody platform-TurboCHO

Image Credit: GenScript

Highlights

  • Availability of multiple isotypes
  • Large capacity
  • Fast delivery in 2 weeks

General workflow

High throughput (HT) gene to antibody platform-TurboCHO

Image Credit: GenScript

Service specifications

Source: GenScript

Perspective Description
Targeting Amount (mAb)
  • 0.1 - 5 mg
  • Other amounts upon request
Turnaround Time As short as 2 weeks
Target Types
  • Recombinant proteins
  • Antibody formats including full-length antibody, Fabs, scFvs, VHHs, or other fragments fused with Fc
QC
  • SDS-PAGE
  • Endotoxin control
  • LC-MS
  • Additional QC options available upon request with charge
Purification
  • 1-step purification (Protein A for antibody targets)
  • Additional purification options available upon request with charge
Additional Services ELISA, Cell-based assay, FACS screening, Octet® BLI assay, Biacore™ SPR assay, etc.

Note:
1. A minimum sample size of 8 is typically needed.
2. 5% of the samples will be chosen randomly for the LC-MS and endotoxin test.

Case studies

High expression titers in multiple isotypes

High throughput (HT) gene to antibody platform-TurboCHO

Image Credit: GenScript

High-purity of antibodies expressed in TurboCHO™ high throughput system

High throughput (HT) gene to antibody platform-TurboCHO

Image Credit: GenScript

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