Histology & Microscopy

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Tiny microscopes give researchers a peek into neural circuitry of social behavior

Tiny microscopes mounted on mice's heads have given researchers a peek into the neural circuitry of social behavior.

1 Nov 2017

Studying the nanomechanical properties of aging and cancerous cells using AFM

An interview with Prof. Igor Sokolov, Tufts University conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 31 Oct 2017

Digital Pathology for Everyone

There are two problems that pathologists face today. The first is, that a pathologist’s diagnosis using tissue sections is becoming more complex. There are many more biomarkers, and clinicians now ask for a more precise diagnosis. Secondly, the number of pathologists worldwide is declining every day, as the profession is often overlooked in favor of other specializations.

From microDimensions - Bramlage Scientific GmbH 27 Oct 2017

Research provides insight into how two stands of double helix separate during replication

Life would be impossible if the DNA in dividing cells were replicated with anything less than near-perfect precision. Every time a nucleated cell commits to becoming two cells, every "letter" of its genome must be replicated once and only once.

24 Oct 2017

Measuring biological samples using SNAP

My group is interested in host pathogen interaction and we mainly focus on how bacteria enter cells. In essence, the idea is that if you can prevent bacteria from entering cells, then you will prevent illness.

From Bruker Nano Surfaces and Metrology 24 Oct 2017

Using AFM to study cell mechanics and function

My lab, broadly speaking, is interested in trying to understand interactions between cells and materials. Those could be materials that are present within living tissue or materials that we use for engineering purposes to try to do something of technological or therapeutic interest.

From Bruker Nano Surfaces and Metrology 17 Oct 2017

Investigating new cancer therapy candidates with live-cell imaging

There are two main things that we've worked on in the lab as regards to drug studies. One is identifying new combinations of drugs, and working on why a combination of drugs should work better than each alone.

From Sartorius 16 Oct 2017

Novel microscopy technique can more accurately diagnose cancer than current methods

A novel microscopy technique to examine tumour tissue in three dimensions can more accurately diagnose cancer than current two-dimensional methods, according to a study conducted at Karolinska Institutet and Karolinska University Hospital in Sweden. The study is published in Nature Biomedical Engineering.

3 Oct 2017

Non-labeling multiphoton microscopy provides highly reliable prediction of cancer malignancy

A new study by Osaka University scientists shows that non-labeling multiphoton microscopy (NL-MPM) can be used for quantitative imaging of cancer that is safe and requires no resection, fixation or staining of tissues.

3 Oct 2017

Life-like color reproduction and virtually noise-free images provided for microscopy with Olympus' SC180

Accelerate your routine microscopy work with the Olympus SC180 microscope camera. With a full 18 megapixels, the SC180 camera delivers the high-resolution images required to make insightful observations.

From Evident Corporation - Life Sciences 29 Sep 2017

Research reveals novel mechanism of ribosome dimerization using cryo-electron microscopy

Antibiotics are the most common medication used to treat microbial infections. Many antibiotics target intracellular bacterial ribosomes - cellular factories that synthesize proteins - which are essential for bacterial survival and proliferation.

28 Sep 2017

BMG LABTECH receives grant for the "Microplate Reader with Linear Variable Filter" patent

BMG LABTECH, a leading manufacturer of microplate readers, announces that the company has received grant for the U.S. Patent 9,733,124, entitled “Microplate Reader with Linear Variable Filter”. The patent’s claims cover a revolutionary new type of dual monochromator technology using Linear Variable Filters (LVF) for the selection of wavelength and bandwidths. The patent provides protection for this unique LVF MonochromatorTM design and recognition of the high quality of the innovation being carried out by the BMG LABTECH team.

From BMG LABTECH GmbH 15 Sep 2017

Scientists use novel microscopy to illuminate chromosomal 'dark matter'

Using a microscope invented at the Marine Biological Laboratory (MBL), a collaborative team of biologists, instrument developers, and computational scientists has for the first time measured the density of a relatively inscrutable, highly condensed form of chromosomal material that appears in the cells of human beings and other eukaryotes.

13 Sep 2017

Optical Microscopy Resolution Revolution

I will talk about the simple but fundamental idea that allowed breaking the diffraction barrier in fluorescence microscopy as well as about MINFLUX nanoscopy, the latest development in the field that for the first time provides true molecular resolution with visible light and standard objective lenses.

From Pittcon 12 Sep 2017

Researchers uncover new structural information on laminin-integrin interaction

While you are what you eat, cells are what they touch. The cells with which it interacts will determine a cell's function, shape, and in some cases even identity.

11 Sep 2017

Seeing the full picture, real-time analysis of live-cells

Every cell is a miniature factory taking in raw material (extracellular signals) and processing it to produce something (a biological response). But unlike a factory that can be easily tweaked to run at steady-state and look the same from day to day, cells are dynamic.

From Sartorius 7 Sep 2017

Differentiating sepsis and systemic inflammatory response syndrome using biomarkers

Firstly, it is necessary to make a distinction between systemic inflammation and Systemic Inflammatory Response Syndrome (SIRS). SIRS consists of changes in clinical signs including an abnormal body temperature, increased heart rate, increased respiratory rate, an abnormal white cell count (either decreased or elevated), or an increase in band neutrophils.

7 Sep 2017

Optical species identification for preservation and species identification

Species identification is important for ecological research and in particular to study the impact of natural hazards or environmental pollutants present, because it’s possible to determine the general health of the ecosystem through the diversity of life that are found in a given area.

From Teledyne Lumenera 22 Aug 2017

Livecyte® Kinetic Cytometer system by Phasefocus wins 2017 Microscopy Today Innovation Award

Phasefocus is the proud recipient of a 2017 Microscopy Today Innovation Award for its Livecyte® Kinetic Cytometer system.

From Phase Focus Limited 11 Aug 2017

Immune ‘hotspots’ could help predict the risk of breast cancer relapse in patients, study finds

Scientists from The Institute of Cancer Research, London has developed a new test through which women at a greater risk of relapsing from breast cancer within 10 years of diagnosis can be identified.

4 Aug 2017