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Protein that appears to play a key role in Alzheimer's disease

A protein that allows human cancer to resist multiple anticancer drugs also appears to play a key role in Alzheimer's disease, according to research conducted at Fox Chase Cancer Center. The protein, active in brain tissue, could be a target for new drugs to treat patients with Alzheimer's.

20 May 2004

Researchers to study link between diabetes and early dementia

Understanding the link between diabetes and early dementia – as well as how diabetes relates to other causes of memory loss – is the focus of a new study at Columbia University Medical Center (CUMC) and approximately 40 other medical institutions nationwide.

20 May 2004

Cell division can be halted in multiple ways, with implications for cancer

Brown University researchers have found that there are multiple independent ways to stop cell division, a phenomenon that prevents the spread of genetic mutation, which can make cells cancerous. Results of this research, along with an accompanying editorial, were published in the current issue of the journal Molecular Cell.

20 May 2004

A genetic variant (MTHFR C677T) puts half the population at increased risk of neural tube defects

Researchers in Ireland and the United States identified the genetic make-up (genotype) of 395 individuals born with neural tube defects (spina bifida or encephalocele) and 848 controls.

20 May 2004

Caffeinated beverages may benefit some people who are at high-risk for liver disease

According to new research presented today at Digestive Disease Week, drinking caffeinated beverages may benefit some people who are at high-risk for liver disease. Conversely, a study by researchers from India found that soda drinkers, who represent a huge percentage of the American population, may actually have an increased risk of developing esophageal cancer.

19 May 2004

Brain can make errors in reassembling the color and motion of objects

You're driving along in your car and catch a glimpse of a green SUV out of the corner of your eye. A few seconds later, you glance over, and to your surprise discover that the SUV is actually brown.

19 May 2004

Inexpensive, simple urine test that could identify impending kidney failure

Johns Hopkins researchers have developed the basis of an inexpensive, simple urine test that identifies impending kidney failure or rejection following transplant surgery. Their work, presented this week in a special invited lecture to the American Transplant Congress in Boston, Mass., is based on proteins found in urine, and could lead to a urine test kit that may allow many patients to skip painful biopsies.

19 May 2004

Closer to understanding the function of a protein linked to an inherited form of the movement disorder dystonia

The protein, torsinA, is defective in patients with DYT1 dystonia, an inherited condition that causes uncontrollable movements in the limbs and torso. Learning what torsinA does could be an important step toward developing a treatment for the disorder.

19 May 2004

Music teachers routinely exposed to noise levels could suffer hearing loss

Led by research associate Alberto Behar and electrical and computer engineering professors Hans Kunov and Willy Wong, the team found that while general noise exposure over the course of an average day is marginally acceptable, noise levels during teaching periods could damage the inner ear.

19 May 2004

Blood pressure control of people 80 years and older, especially women, must be made a national priority

Blood pressure control of people 80 years and older, especially women, must be made a national priority, urged a Northwestern University researcher at the American Society of Hypertension’s Nineteenth Annual Scientific Meeting.

19 May 2004

50 new scientists sought after in the field of biomedical research

The Institute is looking for candidates from the full range of biological and biomedical inquiry who demonstrate exceptional promise early in their careers as independent researchers. Nearly 200 universities, medical schools, and research institutes have been invited to nominate their best scientists for the competition. Between 30 and 50 scientists will be chosen to join the Institute in 2005.

19 May 2004

Inactivating a protective molecule may help chemotherapy for leukemia but harm bone marrow

Inactivating a protective molecule in leukemic cells to make them more vulnerable to chemotherapy might also make healthy blood-forming cells more sensitive to the toxic effects of those same drugs.

19 May 2004

Manipulation of the body’s own natural killer cells to destroy cells containing the HIV virus

Current treatments for HIV block the virus from replicating, but don’t kill the cells that contain HIV. The existence of these HIV-harboring cells -- often called the “latent” or “resting reservoir” -- is regarded by many to be the main obstacle to finding a cure for HIV.

18 May 2004

$1.4 million to investigate how strokes and other events that cut off blood flow to the brain disrupt the blood-brain barrier

The Cleveland Clinic has been awarded a four-year, $1.4 million grant from the National Institutes of Health to investigate how strokes and other events that cut off blood flow to the brain disrupt the blood-brain barrier. Researchers hope to use their findings to develop new methods to limit the damage caused by such events.

17 May 2004

Research into sleeping disorder drug may help multiple sclerosis patients

A University of Nottingham academic is leading a research project looking at whether a drug produced for a sleeping disorder could improve the quality of life for thousands of multiple sclerosis patients.

17 May 2004

Discovery of the gene for Cornelia de Lange syndrome

An international team of researchers has discovered the gene for Cornelia de Lange syndrome, a disabling, multisystem genetic disease that affects an estimated one in 10,000 children. The finding is expected to lead to a genetic test, enabling rapid and definitive diagnosis of the syndrome, as well as prenatal testing for families who already have one child with the disease.

17 May 2004

Researchers make it possible to visualize memories

Researchers at Baylor College of Medicine in Houston have described how memories are made – and they have made it possible for you to see it.

15 May 2004

Genetically engineered viruses may create new class of cancer therapies

A genetically engineered virus can selectively kill cancerous cells in the lung and colon while leaving healthy cells intact, according to new research published today in Cancer Research by William Wold and colleagues at Saint Louis University School of Medicine.

15 May 2004

Cancer-causing gene identified that may play a key role in the development of leukemia and other cancers

Using genetically engineered mice, researchers at the Johns Hopkins Children's Center have identified a gene that functions as a cancer-causing gene (or oncogene) and may play a key role in the development of leukemia and other cancers in children and adults.

15 May 2004

Particles in the air we breathe may pose genetic risks to humans

Particles in the air we breathe may pose genetic risks to humans and wildlife, according to new findings by researchers at McMaster University.

15 May 2004

Medical Research News

Protein that appears to play a key role in Alzheimer's disease

Researchers to study link between diabetes and early dementia

Cell division can be halted in multiple ways, with implications for cancer

A genetic variant (MTHFR C677T) puts half the population at increased risk of neural tube defects

Caffeinated beverages may benefit some people who are at high-risk for liver disease

Brain can make errors in reassembling the color and motion of objects

Inexpensive, simple urine test that could identify impending kidney failure

Closer to understanding the function of a protein linked to an inherited form of the movement disorder dystonia

Music teachers routinely exposed to noise levels could suffer hearing loss

Blood pressure control of people 80 years and older, especially women, must be made a national priority

50 new scientists sought after in the field of biomedical research

Inactivating a protective molecule may help chemotherapy for leukemia but harm bone marrow

Manipulation of the body’s own natural killer cells to destroy cells containing the HIV virus

$1.4 million to investigate how strokes and other events that cut off blood flow to the brain disrupt the blood-brain barrier

Research into sleeping disorder drug may help multiple sclerosis patients

Discovery of the gene for Cornelia de Lange syndrome

Researchers make it possible to visualize memories

Genetically engineered viruses may create new class of cancer therapies

Cancer-causing gene identified that may play a key role in the development of leukemia and other cancers

Particles in the air we breathe may pose genetic risks to humans

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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