Molecular & Structural Biology

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AI tool helps develop the most complete map of the bacterial essential interactome

Universitat Autonoma de Barcelona (UAB) researchers have produced the most complete map of the bacterial essential interactome, i.e. how proteins combine and interact to perform functions essential for their survival.

23 Feb 2024

Advancing gene regulatory network inference with causal discovery and graph neural networks

Gene regulatory networks (GRNs) depict the regulatory mechanisms of genes within cellular systems as a network, offering vital insights for understanding cell processes and molecular interactions that determine cellular phenotypes.

23 Feb 2024

Digital DNA melting analysis can be a faster and more reliable tool for pathogen detection

A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis.

21 Feb 2024

Molecular glue could pave the way for new generation of drugs

A breakthrough class of molecular glue identified at the University of Dundee could pave the way for a new generation of drugs to target cancers and neurodegenerative diseases.

21 Feb 2024

IκBζ protein holds potential for treating autoimmune conditions

Our immune system is remarkably powerful. It quickly assembles teams of cells to eliminate threats inside our bodies.

21 Feb 2024

Discovery of novel enzyme family holds potential for antibiotic development

Researchers at Umeå University in Sweden, led by Professor Felipe Cava, have identified a new family of enzymes that creates a unique type of cross-linking between the building blocks of bacterial cell walls.

19 Feb 2024

AI revolutionizes protein function prediction with "DeepGO-SE"

Researchers developed "DeepGO-SE," a novel AI method for predicting protein functions from sequences, significantly outperforming traditional models by incorporating gene ontology and protein-protein interactions.

15 Feb 2024

GV1001 exerts anti-aging effects in triple transgenic Alzheimer's mice

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 3, entitled, "GV1001 reduces neurodegeneration and prolongs lifespan in 3xTg-AD mouse model through anti-aging effects."

15 Feb 2024

Breaking through new research barriers with iPSC technology

In this interview, we speak to Keith Olson and Coby Carlson from Fujifilm Cellular Dynamics about their iPSC technology.

From FUJIFILM Cellular Dynamics 15 Feb 2024

Researchers discover new mechanism of action between the nutrient adaptation of intestinal stem cells and aging

Researchers used an organ-wide approach to quantitatively analyze cell number, size, and identity regulation upon nutrient-induced tissue adaptation of the Drosophila midgut.

15 Feb 2024

COVID-19's lasting impact on smell and brain health unveiled

Study reviews the impact of COVID-19 on olfactory dysfunction and its link to neurocognitive disorders, highlighting MRI findings and potential treatments for smell loss.

12 Feb 2024

Genetics of estrogen production linked to endometrial cancer risk in postmenopausal women

A study in eBioMedicine identifies genetic factors regulating blood estrone levels in postmenopausal women, linking specific genetic loci to an increased risk of endometrial cancer, highlighting the role of non-ovarian estrogen production in cancer development.

11 Feb 2024

Decoding the differences between two vital RNA transport complexes

Genetic expression, often leading to protein synthesis, requires a complex coordination of molecular machinery across several stages.

8 Feb 2024

Researchers identify a new approach to controlling bacterial infections

Researchers at the Icahn School of Medicine at Mount Sinai have identified a new approach to controlling bacterial infections.

7 Feb 2024

Researchers introduce new approach for accurately assessing cell composition in the pancreas

Research introduces new DNA methylation-based method for accurately assessing cell composition in the human pancreas, addressing a critical gap in diabetes research.

7 Feb 2024

Researchers develop new approach to improve the accuracy of RNA sequencing

A team at NDORMS, University of Oxford has developed a new approach to significantly improve the accuracy of RNA sequencing.

7 Feb 2024

Unraveling the architecture of poxvirus cores

A recent re-emergence and outbreak of Mpox brought poxviruses back as a public health threat, underlining an important knowledge gap at their core.

6 Feb 2024

Bioprinting breakthrough: Tech platform creates 3D neural tissues in which neurons and glia connect

Researchers produced 3D bioprinted human brain tissues, allowing for the creation of functioning neural networks that could simulate network activity in normal and pathological situations.

6 Feb 2024

Shared molecular pathways found in Alzheimer's and epilepsy

Study reveals shared brain proteomic signatures in Alzheimer’s disease and epilepsy, suggesting common molecular mechanisms that could pave the way for unified therapeutic strategies.

5 Feb 2024

Scientists pinpoint two cell-surface proteins that partner to spur cancer cell growth

Scientists at City of Hope®, one of the largest cancer research and treatment organizations in the United States, have discovered a new cellular mechanism that plays an important role in cancer cells' ability to cause disease. The study was published in Nature Structural & Molecular Biology today.

5 Feb 2024

Molecular & Structural Biology

AI tool helps develop the most complete map of the bacterial essential interactome

Advancing gene regulatory network inference with causal discovery and graph neural networks

Digital DNA melting analysis can be a faster and more reliable tool for pathogen detection

Molecular glue could pave the way for new generation of drugs

IκBζ protein holds potential for treating autoimmune conditions

Discovery of novel enzyme family holds potential for antibiotic development

AI revolutionizes protein function prediction with "DeepGO-SE"

GV1001 exerts anti-aging effects in triple transgenic Alzheimer's mice

Breaking through new research barriers with iPSC technology

Researchers discover new mechanism of action between the nutrient adaptation of intestinal stem cells and aging

COVID-19's lasting impact on smell and brain health unveiled

Genetics of estrogen production linked to endometrial cancer risk in postmenopausal women

Decoding the differences between two vital RNA transport complexes

Researchers identify a new approach to controlling bacterial infections

Researchers introduce new approach for accurately assessing cell composition in the pancreas

Researchers develop new approach to improve the accuracy of RNA sequencing

Unraveling the architecture of poxvirus cores

Bioprinting breakthrough: Tech platform creates 3D neural tissues in which neurons and glia connect

Shared molecular pathways found in Alzheimer's and epilepsy

Scientists pinpoint two cell-surface proteins that partner to spur cancer cell growth

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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