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Study shows antipsychotic drugs increase health risks in dementia patients

Study found that antipsychotic drug use in dementia patients is linked to increased risks of stroke, heart failure, and other serious conditions.

18 Apr 2024

ChatGPT shows promise in polypharmacy management

Polypharmacy, or the concurrent use of five or more medications, is common in older adults and increases the risk of adverse drug interactions.

18 Apr 2024

Antipsychotics for dementia associated with elevated risks of serious adverse outcomes

Antipsychotic use in people with dementia is associated with elevated risks of a wide range of serious adverse outcomes including stroke, blood clots, heart attack, heart failure, fracture, pneumonia, and acute kidney injury, compared with non-use, finds a study published by The BMJ today.

17 Apr 2024

New vaccine promises broad protection against SARS-CoV-2 and other sarbecoviruses

Researchers at Georgia Tech and the University of Wisconsin have created a broad-spectrum vaccine capable of defending against various SARS-CoV-2 variants and related bat coronaviruses.

17 Apr 2024

To stop fentanyl deaths in Philadelphia, knocking on doors and handing out overdose kits

On a narrow street lined with row houses and an auto body shop in the Kensington neighborhood of North Philadelphia, Marsella Elie climbs a home's front steps and knocks hard on the door.

17 Apr 2024

Common HIV drugs linked to reduced Alzheimer's disease risk

Alzheimer's disease (AD) currently afflicts nearly seven million people in the U.S. With this number expected to grow to nearly 13 million by 2050, the lack of meaningful therapies represents a major unmet medical need.

16 Apr 2024

Study shows potential for universal flu vaccine with broad antibody response

Study discusses the potential of universal influenza vaccines, emphasizing the importance of antibody breadth and Fc receptor (FcR) effector functions in protecting against various influenza strains, including those with pandemic potential.

15 Apr 2024

Ketamine's rapid impact on depression linked to immune system pathways

Study reveals ketamine's potent anti-inflammatory effects on neurological disorders, showing promise for treating major depressive disorder through modulation of neuroimmune pathways.

15 Apr 2024

Epilepsy drug prevents brain tumor formation and growth in mouse models of NF1

A drug used to treat children with epilepsy prevents brain tumor formation and growth in two mouse models of neurofibromatosis type 1 (NF1), according to a study by researchers at Washington University School of Medicine in St. Louis.

15 Apr 2024

Antibiotics ineffective for cough treatment in lower respiratory tract infections

Use of antibiotics provided no measurable impact on the severity or duration of coughs even if a bacterial infection was present, finds a large, prospective study of people who sought treatment in U.S. primary or urgent care settings for lower-respiratory tract infections.

15 Apr 2024

Restoring insulin sensitivity without TZD side effects

Thiazolidinediones (TZDs) are a class of drug that can be used to treat type 2 diabetes by reversing insulin resistance, one of the main hallmarks of the disease.

13 Apr 2024

Cannabis compound d-limonene reduces anxiety-inducing effects of THC

A Johns Hopkins Medicine-led research team has added to evidence that a chemical found naturally in cannabis (also known as marijuana) can -; in the right amounts -; lessen the anxiety-inducing effects of tetrahydrocannabinol (THC), the primary psychoactive sister chemical found in cannabis.

12 Apr 2024

Is psilocybin safe for treating depression and anxiety?

A study in JAMA Network Open examined the acute adverse effects of therapeutic doses of psilocybin for treating depression and anxiety, focusing on its safety profile by assessing the occurrence of immediate side effects like headache, nausea, and elevated blood pressure among others.

12 Apr 2024

Annual COVID-19 vaccine proves to be a wise investment for personal health and pocketbook

Study finds that receiving an annual COVID-19 vaccine is clinically and economically beneficial for individuals, regardless of insurance status, offering savings by reducing the likelihood of infection and its associated costs.

11 Apr 2024

Popular diabetes drugs not linked to thyroid cancer risk, study finds

SGLT2 inhibitors: A game-changer in preventing heart failure and sudden cardiac deaths

study reveals that SGLT2 inhibitors consistently lower the risk of major adverse cardiovascular events by 9% across various patient groups, especially impacting cardiovascular death reduction, highlighting their broad therapeutic potential beyond diabetes management.

9 Apr 2024

Nirmatrelvir fails to shorten COVID-19 symptoms in latest trial

A study in The New England Journal of Medicine evaluates the combination of nirmatrelvir and ritonavir against COVID-19, finding it does not significantly reduce symptom duration in vaccinated or unvaccinated adult outpatients.

8 Apr 2024

DEPOSITION trial evaluates the use of topical tranexamic acid during heart surgery

Administering tranexamic acid (TxA), a drug used to reduce bleeding during heart surgery, topically rather than intravenously did not meet its primary endpoint of reducing seizures and was stopped early due to an increased risk of bleeding events, according to research presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

ACE inhibitors show no benefit in reducing chemotherapy-induced heart damage

Patients who took an angiotensin-converting enzyme (ACE) inhibitor while undergoing cancer treatment with high-dose anthracycline chemotherapy did not show any difference in troponin T levels, a biomarker associated with heart damage, at one month after their last chemotherapy dose compared with those who did not take an ACE inhibitor, according to a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Study shows reduced bleeding risk with ticagrelor monotherapy after percutaneous coronary intervention

People who have had a heart attack or who are at risk for a heart attack and who stopped taking aspirin alongside the P2Y12 inhibitor ticagrelor one month after undergoing percutaneous coronary intervention (PCI) saw a significantly reduced risk of clinically meaningful bleeding with no increased risk of clotting-related adverse events at 12 months compared with patients who continued taking aspirin and ticagrelor for a full year, in a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Pharmaceutical News

Study shows antipsychotic drugs increase health risks in dementia patients

ChatGPT shows promise in polypharmacy management

Antipsychotics for dementia associated with elevated risks of serious adverse outcomes

New vaccine promises broad protection against SARS-CoV-2 and other sarbecoviruses

To stop fentanyl deaths in Philadelphia, knocking on doors and handing out overdose kits

Common HIV drugs linked to reduced Alzheimer's disease risk

Study shows potential for universal flu vaccine with broad antibody response

Ketamine's rapid impact on depression linked to immune system pathways

Epilepsy drug prevents brain tumor formation and growth in mouse models of NF1

Antibiotics ineffective for cough treatment in lower respiratory tract infections

Restoring insulin sensitivity without TZD side effects

Cannabis compound d-limonene reduces anxiety-inducing effects of THC

Is psilocybin safe for treating depression and anxiety?

Annual COVID-19 vaccine proves to be a wise investment for personal health and pocketbook

Popular diabetes drugs not linked to thyroid cancer risk, study finds

SGLT2 inhibitors: A game-changer in preventing heart failure and sudden cardiac deaths

Nirmatrelvir fails to shorten COVID-19 symptoms in latest trial

DEPOSITION trial evaluates the use of topical tranexamic acid during heart surgery

ACE inhibitors show no benefit in reducing chemotherapy-induced heart damage

Study shows reduced bleeding risk with ticagrelor monotherapy after percutaneous coronary intervention

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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