Pharmacology News and Research

Latest Pharmacology News and Research

Study demonstrates chemo-preventive properties of alpha-santalol against prostate cancer development

Extracted from the core of sandalwood trees (santalum album tree), sandalwood oil has been used for many centuries by several cultures throughout the world for perfume, soaps, incense and candles.

13 Feb 2024

Scientists discover how oxytocin influences memory in animals

Oxytocin (OXT) is a hormone that is known for its effects on psychological well-being and emotional bonding in animals.

13 Feb 2024

Breakthrough technique unveils secrets of "backtracking" in gene regulation

A technique can determine for the first time how frequently, and exactly where, a molecular event called "backtracking" occurs throughout the genetic material (genome) of any species, a new study shows.

9 Feb 2024

Rucaparib and its major metabolite exhibit differential biological activity and synergy

Once they enter the body, drugs, apart from carrying out their therapeutic function, are biochemically transformed by the action of the metabolic machinery, a process that facilitates their expulsion.

9 Feb 2024

DDT exposure found to alter sperm epigenome in humans

In a study that signals potential reproductive and health complications in humans, now and for future generations, researchers from McGill University, the University of Pretoria, Université Laval, Aarhus University, and the University of Copenhagen, have concluded that fathers exposed to environmental toxins, notably DDT, may produce sperm with health consequences for their children.

9 Feb 2024

Wayne State researchers secure $1.4 million DoD grant for prostate cancer study

A team of researchers from Wayne State University was awarded a $1.4 million, three-year grant from the U.S. Department of Defense for the study, "Cytochrome c acetylation drives prostate cancer aggressiveness and Warburg effect."

7 Feb 2024

New tool can help researchers to better understand the metabolism of microorganisms

Researchers from University of California San Diego, as part of a large collaboration with scientists around the world, have developed a new search tool to help researchers better understand the metabolism of microorganisms.

6 Feb 2024

RvT4 molecule boosts the body's defenses against atherosclerosis in rheumatoid arthritis patients

Researchers from Queen Mary University of London have found that the molecule RvT4 enhances the body's natural defences against atherosclerosis (hardening of the arteries) in patients with rheumatoid arthritis.

6 Feb 2024

Proteogenomics provides clues about drug response in acute myeloid leukemia

Doctors have nearly a dozen new targeted drugs to treat patients with acute myeloid leukemia, or AML, yet three of four patients still die within five years.

6 Feb 2024

Researchers identify the basic principles of serotonin transport in nerve cells

Drugs known as antidepressants target the serotonin transporter in nerve cells and are among the most commonly prescribed medicines worldwide, but are sometimes associated with significant side effects.

5 Feb 2024

PI3K/AKT and MEK/ERK pathways targeted in new therapy for docetaxel-resistant prostate cancer

A team of researchers from the Badalona Applied Research Group in Oncology (B·ARGO) and the Urologic Tumours Unit of the Institut Català d'Oncologia (ICO) and the Germans Trias i Pujol Research Institute (IGTP) have found a new therapeutic strategy for patients with a specific subtype of metastatic prostate cancer resistant to standard chemotherapy treatment with docetaxel.

5 Feb 2024

Small-molecule A485 mobilizes white blood cells on demand

New study reveals a small molecule that can selectively mobilize white blood cells, offering potential treatments for diseases with abnormal leukocyte counts.

3 Feb 2024

Proteogenomics reveals new target for beating drug resistance in acute myeloid leukemia

Doctors have nearly a dozen new targeted drugs to treat patients with acute myeloid leukemia, or AML, yet three of four patients still die within five years.

2 Feb 2024

UH researcher aims to revolutionize treatment regimens for triple-negative breast cancer

A researcher at the University of Houston College of Pharmacy Drug Discovery Institute is working to revolutionize treatment regimens for triple-negative breast cancer (TNBC) by proving that nebivolol, an FDA-approved drug for high blood pressure, is effective in treating it.

31 Jan 2024

Female sex hormone estradiol makes women more susceptible to cocaine addiction

Previous studies focused on cocaine use have found that women are more likely than men to develop an addiction, try cocaine at a younger age, use larger amounts of the drug, and suffer from overdose.

30 Jan 2024

Using AI to break the opioid addiction cycle

When Ben Brown, research assistant professor of chemistry, thinks about the opioid epidemic, he views the problem on a molecular level.

19 Jan 2024

UNC scientists develop "smart" patch for precision drug delivery

University of North Carolina at Chapel Hill scientists created a new drug delivery system, called the Spatiotemporal On-Demand Patch (SOP), which can receive commands wirelessly from a smartphone or computer to schedule and trigger the release of drugs from individual microneedles.

18 Jan 2024

Understanding antimicrobial resistance in hospital-acquired pneumonia

New research has been published that identifies positive steps towards a better understanding of antimicrobial resistance (AMR), specifically in hospital-acquired pneumonia (HAP).

18 Jan 2024

Natural PLA2 inhibitor from marine fungus combats fatty liver disease by silencing lipotoxic pathways

This new article publication from Acta Pharmaceutica Sinica B, discusses the identification of a natural PLA2 inhibitor from the marine fungus Aspergillus sp. c1 for MAFLD treatment that suppressed lipotoxicity by inhibiting the IRE-1α/XBP-1s axis and JNK signaling.

16 Jan 2024

10 years of University of Kentucky's Healthy Hearts for Women takes aim at heart disease

The University of Kentucky will mark a decade of raising awareness and continuing its effort to warn women about the dangers of heart disease with the annual Healthy Hearts for Women Symposium.

12 Jan 2024

Pharmacology News and Research

Latest Pharmacology News and Research

Study demonstrates chemo-preventive properties of alpha-santalol against prostate cancer development

Scientists discover how oxytocin influences memory in animals

Breakthrough technique unveils secrets of "backtracking" in gene regulation

Rucaparib and its major metabolite exhibit differential biological activity and synergy

DDT exposure found to alter sperm epigenome in humans

Wayne State researchers secure $1.4 million DoD grant for prostate cancer study

New tool can help researchers to better understand the metabolism of microorganisms

RvT4 molecule boosts the body's defenses against atherosclerosis in rheumatoid arthritis patients

Proteogenomics provides clues about drug response in acute myeloid leukemia

Researchers identify the basic principles of serotonin transport in nerve cells

PI3K/AKT and MEK/ERK pathways targeted in new therapy for docetaxel-resistant prostate cancer

Small-molecule A485 mobilizes white blood cells on demand

Proteogenomics reveals new target for beating drug resistance in acute myeloid leukemia

UH researcher aims to revolutionize treatment regimens for triple-negative breast cancer

Female sex hormone estradiol makes women more susceptible to cocaine addiction

Using AI to break the opioid addiction cycle

UNC scientists develop "smart" patch for precision drug delivery

Understanding antimicrobial resistance in hospital-acquired pneumonia

Natural PLA2 inhibitor from marine fungus combats fatty liver disease by silencing lipotoxic pathways

10 years of University of Kentucky's Healthy Hearts for Women takes aim at heart disease

Pittcon Highlights: Pharmaceutical & Biologic eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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