The field of in vivo, deep-tissue imaging is constantly advancing. In order to keep up with experimental breakthroughs, appropriate imaging systems should be designed with flexibility in mind. This video highlights the beam path options that help achieve this experimental flexibility on the Sutter Instrument Movable Objective Microscope® (MOM®).
Beam Paths of the Movable Objective Microscope (MOM)
Deep-tissue imaging systems often need to combine multi-photon laser imaging in concert with optogenetic stimulation of the sample. Additionally, some experiments require one or more manipulators around the animal for simultaneous electrophysiology. While individual imaging systems are unique, it is crucial not to get locked into a design that limits future modification.
The open design of the Sutter MOM allows for easy integration of alternate beam paths and the system provides an ideal platform for designing unique in vivo imaging experiments. The Sutter MOM can be easily reconfigured to allow for evolving research. Several typical applications are shown.