Pharmaceutical News

RSS

N-acetylcysteine protects against acyclovir-induced nephrotoxicity

Oxidative stress could be a key process in acyclovir (ACV)-induced nephrotoxicity. N-acetylcysteine (NAC) is a water-soluble antioxidant with anti-inflammatory activity.

18 Apr 2025

Study: Women show greater awareness of obesity drugs than men

New research to be presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) shows that women are much more aware of knowledgeable about the obesity drugs GLP-1/GIP receptor agonists (that include semaglutide and tirzepatide).

17 Apr 2025

GLP1 agonists linked to depression risk in new genetic study

A groundbreaking study published in the journal Current Neuropharmacology highlights a concerning potential link between Glucagon-like Peptide-1 (GLP1) receptor agonists-widely used in blockbuster drugs like Ozempic-and the risk of depression and suicidal ideation (SI).

17 Apr 2025

Researchers link 9 blood proteins to breast cancer and suggest 3 drugs for repurposing

Researchers used integrated Mendelian randomization in a cohort of over 247,000 individuals to identify 62 plasma proteins associated with breast cancer risk. Nine high-confidence targets, including ULK3 and CSK, showed potential for drug repurposing and immune pathway regulation.

16 Apr 2025

Diabetes medications may help shield the brain from cognitive decline

A study led by researchers in the University of Florida College of Pharmacy has found that a pair of popular glucose-lowering medications may have protective effects against the development of Alzheimer's disease and related dementias in patients with Type 2 diabetes.

16 Apr 2025

Safe and simple ways to dispose of unused medicines

Is your medicine cabinet full of expired drugs or medications you no longer use? The best way to dispose of most types of expired, unwanted or unused medicines is through a drug take-back program.

16 Apr 2025

Prolonging pain relief in surgery with dexmedetomidine and spinal anesthesia

Spinal anesthesia is widely used to numb patients during surgery, but its effects sometimes wear off too soon.

16 Apr 2025

New findings highlight a shifting landscape for weight loss and glucose managing medications

When it comes to managing weight loss and type 2 diabetes with medications, research shows that it's out with the old and in with the new.

15 Apr 2025

Reserpine shows promise in treating retinitis pigmentosa in rat studies

New studies in rats suggest the drug reserpine, approved in 1955 for high blood pressure, might treat the blinding disease retinitis pigmentosa.

15 Apr 2025

Assessing the effectiveness of azvudine and paxlovid in hospitalized COVID-19 patients aged over 60

This new article publication from Acta Pharmaceutica Sinica B, discusses a retrospective cohort study of the efficacy and safety of oral azvudine versus nirmatrelvir/ritonavir in elderly hospitalized COVID-19 patients aged over 60 years.

14 Apr 2025

Selective depletion of PD-1 positive lymphocytes using a novel bispecific killer engager

This new article publication from Acta Pharmaceutica Sinica B, discusses a bispecific killer engager for targeted depletion of PD-1 positive lymphocytes.

14 Apr 2025

COVID-19 treatments show minimal serious side effects

Numerous treatment options for COVID-19 have been approved by the U.S. Food and Drug Administration over the last four years, including antiviral drugs and monoclonal antibodies that suppress an excessive immune response.

11 Apr 2025

New quinoline-based antiviral shows strong promise against SARS-CoV-2

Researchers develop quinoline-based drug with inhibitory activity against the SARS-CoV-2 papain-like protease (PLpro).

10 Apr 2025

Scientists stop long-COVID symptoms in mice using a new antiviral compound

Australian scientists developed a novel antiviral that targets the SARS-CoV-2 PLpro enzyme, showing strong preclinical efficacy in reducing both acute and long COVID symptoms in mice.

9 Apr 2025

Semaglutide linked to higher risk of vision problems, FDA data analysis shows

Researchers from the University of Bern analyzed over 300,000 FDA reports and found semaglutide use was linked to a higher reporting rate of vision impairment. The findings call for further study into the ocular risks of this widely prescribed diabetes and weight loss drug.

8 Apr 2025

Enfortumab vedotin and pembrolizumab show major benefits for urothelial carcinoma patients

Urothelium is the term for the mucous membrane that lines the urinary tract. This includes the renal pelvis, ureter, urinary bladder and the upper part of the urethra. In the vast majority of cases, urothelial carcinomas grow in the bladder (bladder carcinoma).

4 Apr 2025

Shingles vaccine cuts dementia risk by 20%, new study shows

A large natural experiment shows that the herpes zoster vaccine reduces dementia diagnoses by 20% over seven years. The findings suggest both viral suppression and immune training may play roles in brain health.

3 Apr 2025

Gut bacteria may reduce the effectiveness of common medications

A new study, published today in Nature Chemistry by researchers from the University of Pittsburgh and Yale University, shows how common gut bacteria can metabolize certain oral medications that target cellular receptors called GPCRs, potentially rendering these important drugs less effective.

3 Apr 2025

Study shows long-term benefits of medicinal cannabis for chronic health conditions

Patients prescribed medicinal cannabis in Australia maintained improvements in overall health-related quality of life (HRQL), fatigue, and sleep disturbance across a one-year period, according to a study published April 2, 2025, in the open-access journal PLOS One by Margaret-Ann Tait from The University of Sydney, Australia, and colleagues.

2 Apr 2025

US FDA approves first treatment for hyperphagia in Prader-Willi syndrome

The United States Food and Drug Administration (US FDA) has approved VYKAT™ XR, a significant milestone as the first approved treatment for hyperphagia in Prader-Willi syndrome (PWS).

2 Apr 2025