Pharmaceutical News

RSS

AI-designed drug ISM5939 granted IND clearance for cancer clinical trials

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, announced that it has received IND clearance from FDA for ISM5939, a potential best-in-class oral small molecule inhibitor targeting ENPP1 for the treatment of solid tumors.

22 Nov 2024

Anti-obesity drugs increase food waste in some users

Taking anti-obesity drugs has led some U.S. adults to throw away more food than they tossed before starting the medications, a new study has found.

22 Nov 2024

UVA researchers discover how blood pressure medications affect kidneys

University of Virginia School of Medicine researchers have discovered how long-term treatment of high blood pressure with commonly prescribed drugs can destroy the kidney's ability to filter and purify blood.

21 Nov 2024

Modified darobactin offers hope for combatting antibiotic-resistant bacteria

Antibacterial drugs are important for treating infections. But increasingly, bacterial resistance to current drugs -; so they don't work well, or even at all -; means new ones are urgently needed.

21 Nov 2024

Study projects global antibiotic use to rise by over 50% by 2030

A study reveals a 20.9% rise in global antibiotic use from 2016 to 2023, with middle-income countries leading the increase and highlighting resistance issues.

21 Nov 2024

Antiseizure medications in pregnancy tied to child neurodevelopment risks

Researchers investigate how anti-seizure medication use during pregnancy may increase the risk of neuropsychological conditions in children.

20 Nov 2024

Diabetes drugs cut asthma attacks by up to 70%, reshaping treatment options

Metformin and GLP-1 receptor agonists significantly reduce asthma attacks in patients with type 2 diabetes, offering potential new treatments for asthma.

19 Nov 2024

Low-dose ketamine may be an effective adjunct analgesic to morphine for managing acute pain

A new study that investigates low-dose ketamine (LDK) as an adjunct to morphine for treating acute pain has been published in the October issue of Academic Emergency Medicine (AEM), the peer-reviewed journal of the Society for Academic Emergency Medicine (SAEM).

19 Nov 2024

Common cardiovascular drugs linked to lower risk of dementia

Common cardiovascular drugs are linked to a lower risk of dementia in older age, according to a new study from Karolinska Institutet published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

19 Nov 2024

Study provides insight into how low-dose ketamine alleviates symptoms of major depression

University at Buffalo neuroscientists have identified the binding site of low-dose ketamine, providing critical insight into how the medication, often described as a wonder drug, alleviates symptoms of major depression in as little as a few hours with effects lasting for several days.

19 Nov 2024

Global analysis highlights antibiotic consumption trends and AMR threat

A new study highlights recent, but fluctuating, growth in global human antibiotic consumption, one of the main drivers of growing antimicrobial resistance (AMR).

19 Nov 2024

Peptide hydrogel boosts antibiotic effectiveness against resistant bacteria

Research from Chalmers University of Technology, Sweden, shows that resistant bacteria can regain susceptibility to antibiotics when the treatment is combined with a material equipped with antibacterial peptides.

19 Nov 2024

Anti-obesity drugs show promise in improving cardiovascular health beyond weight loss

Popular anti-obesity drugs continue to show cardiovascular benefits beyond weight loss, according to several new papers published in JACC, the flagship journal of the American College of Cardiology, that are being simultaneously presented at the American Heart Association's 2024 Scientific Sessions.

19 Nov 2024

Multiple sclerosis drug could help individuals with reduced working memory

Fampridine is currently used to improve walking ability in multiple sclerosis. A new study shows that it could also help individuals with reduced working memory, as seen in mental health conditions like schizophrenia or depression.

19 Nov 2024

New 'spray on, wash off' bandages could revolutionize treatment for Epidermolysis Bullosa

Research into new bandaging aims to ease the agony experienced by those living with genetic skin condition Epidermolysis Bullosa (EB), commonly referred to as 'butterfly skin'.

18 Nov 2024

Blood pressure control improved with dual medication pills in India

Medication variations that combined two of three different blood pressure-lowering medications into a single pill worked equally well in reducing blood pressure and were safe among adults in India, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

Hypertension drug may reduce heart failure risk in people recovering from heart attack

New research found that the medication spironolactone, often prescribed for hypertension (high blood pressure), may reduce the risk of heart failure in people recovering from a heart attack.

18 Nov 2024

Edoxaban proves effective in preventing blood clots, stroke after heart valve surgery

Edoxaban, an oral anticoagulant, was equally or more effective than warfarin in reducing the risk of stroke and blood clots for patients after heart valve replacement surgery, according to preliminary late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

Anticoagulants fail to reduce cognitive decline in younger adults with AFib

Prescribing anti-clotting medications to adults younger than age 65 who have atrial fibrillation (AFib) but no other risk factors for stroke did not reduce the risk of cognitive decline, stroke or transient ischemic attack (TIA), according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

SGLT2 inhibitor canagliflozin shown to improve kidney oxygenation in diabetes patients

Type 2 diabetes can lead to diabetic kidney disease, but a class of drugs that cause the kidneys to remove glucose through urine has been gaining attention.

18 Nov 2024